| Full name: nucleosome assembly protein 1 like 1 | Alias Symbol: NRP|NAP1|NAP1L|MGC8688|MGC23410 | ||
| Type: protein-coding gene | Cytoband: 12q21.1 | ||
| Entrez ID: 4673 | HGNC ID: HGNC:7637 | Ensembl Gene: ENSG00000187109 | OMIM ID: 164060 |
| Drug and gene relationship at DGIdb | |||
Expression of NAP1L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAP1L1 | 4673 | 208752_x_at | -0.1303 | 0.7768 | |
| GSE20347 | NAP1L1 | 4673 | 213864_s_at | 0.3859 | 0.0033 | |
| GSE23400 | NAP1L1 | 4673 | 208752_x_at | 0.5207 | 0.0000 | |
| GSE26886 | NAP1L1 | 4673 | 212967_x_at | 0.8566 | 0.0000 | |
| GSE29001 | NAP1L1 | 4673 | 212967_x_at | 0.1309 | 0.6240 | |
| GSE38129 | NAP1L1 | 4673 | 208752_x_at | 0.3296 | 0.0086 | |
| GSE45670 | NAP1L1 | 4673 | 208752_x_at | -0.1768 | 0.2999 | |
| GSE53622 | NAP1L1 | 4673 | 102514 | -0.0498 | 0.5993 | |
| GSE53624 | NAP1L1 | 4673 | 102514 | 0.0919 | 0.2203 | |
| GSE63941 | NAP1L1 | 4673 | 212967_x_at | -0.2427 | 0.5231 | |
| GSE77861 | NAP1L1 | 4673 | 212967_x_at | 0.5028 | 0.0854 | |
| GSE97050 | NAP1L1 | A_21_P0011142 | 0.0111 | 0.9686 | ||
| SRP007169 | NAP1L1 | 4673 | RNAseq | 1.4647 | 0.0000 | |
| SRP008496 | NAP1L1 | 4673 | RNAseq | 1.4891 | 0.0000 | |
| SRP064894 | NAP1L1 | 4673 | RNAseq | 0.2528 | 0.0620 | |
| SRP133303 | NAP1L1 | 4673 | RNAseq | 0.2520 | 0.0469 | |
| SRP159526 | NAP1L1 | 4673 | RNAseq | 0.1283 | 0.5794 | |
| SRP193095 | NAP1L1 | 4673 | RNAseq | 0.2709 | 0.0514 | |
| SRP219564 | NAP1L1 | 4673 | RNAseq | -0.0423 | 0.8987 | |
| TCGA | NAP1L1 | 4673 | RNAseq | 0.0822 | 0.0448 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NAP1L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAP1L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAP1L1 | 4673 | 3 | 3 | 24 | |
| GSE20123 | NAP1L1 | 4673 | 3 | 3 | 24 | |
| GSE43470 | NAP1L1 | 4673 | 3 | 1 | 39 | |
| GSE46452 | NAP1L1 | 4673 | 8 | 1 | 50 | |
| GSE47630 | NAP1L1 | 4673 | 10 | 1 | 29 | |
| GSE54993 | NAP1L1 | 4673 | 0 | 5 | 65 | |
| GSE54994 | NAP1L1 | 4673 | 5 | 2 | 46 | |
| GSE60625 | NAP1L1 | 4673 | 0 | 0 | 11 | |
| GSE74703 | NAP1L1 | 4673 | 3 | 1 | 32 | |
| GSE74704 | NAP1L1 | 4673 | 2 | 2 | 16 | |
| TCGA | NAP1L1 | 4673 | 14 | 15 | 67 |
Total number of gains: 51; Total number of losses: 34; Total Number of normals: 403.
Somatic mutations of NAP1L1:
Generating mutation plots.
Highly correlated genes for NAP1L1:
Showing top 20/1232 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAP1L1 | DDX55 | 0.830163 | 3 | 0 | 3 |
| NAP1L1 | ZSCAN21 | 0.828023 | 4 | 0 | 4 |
| NAP1L1 | ZNF121 | 0.825929 | 3 | 0 | 3 |
| NAP1L1 | RPS19BP1 | 0.822013 | 3 | 0 | 3 |
| NAP1L1 | SLC41A1 | 0.81767 | 3 | 0 | 3 |
| NAP1L1 | BUD31 | 0.817036 | 3 | 0 | 3 |
| NAP1L1 | RP9 | 0.808536 | 3 | 0 | 3 |
| NAP1L1 | ZNRF3 | 0.800673 | 3 | 0 | 3 |
| NAP1L1 | CRLS1 | 0.796125 | 3 | 0 | 3 |
| NAP1L1 | TMEM140 | 0.792633 | 3 | 0 | 3 |
| NAP1L1 | THUMPD2 | 0.791991 | 3 | 0 | 3 |
| NAP1L1 | DMTF1 | 0.787239 | 3 | 0 | 3 |
| NAP1L1 | PPP1R35 | 0.783397 | 3 | 0 | 3 |
| NAP1L1 | MRPS26 | 0.783293 | 3 | 0 | 3 |
| NAP1L1 | MAD2L2 | 0.780189 | 3 | 0 | 3 |
| NAP1L1 | PGAP1 | 0.779754 | 3 | 0 | 3 |
| NAP1L1 | SIX4 | 0.76967 | 3 | 0 | 3 |
| NAP1L1 | EIF2D | 0.768915 | 3 | 0 | 3 |
| NAP1L1 | PHF20 | 0.768007 | 3 | 0 | 3 |
| NAP1L1 | NOM1 | 0.766855 | 3 | 0 | 3 |
For details and further investigation, click here
