| Full name: diacylglycerol kinase delta | Alias Symbol: KIAA0145|DGKdelta | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 8527 | HGNC ID: HGNC:2851 | Ensembl Gene: ENSG00000077044 | OMIM ID: 601826 |
| Drug and gene relationship at DGIdb | |||
Expression of DGKD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGKD | 8527 | 208072_s_at | 0.4830 | 0.2519 | |
| GSE20347 | DGKD | 8527 | 208072_s_at | 0.3708 | 0.0019 | |
| GSE23400 | DGKD | 8527 | 208072_s_at | 0.0767 | 0.0736 | |
| GSE26886 | DGKD | 8527 | 208072_s_at | 0.5344 | 0.0003 | |
| GSE29001 | DGKD | 8527 | 208072_s_at | 0.3291 | 0.0964 | |
| GSE38129 | DGKD | 8527 | 208072_s_at | 0.1083 | 0.6134 | |
| GSE45670 | DGKD | 8527 | 208072_s_at | 0.0601 | 0.7589 | |
| GSE53622 | DGKD | 8527 | 125704 | 0.1345 | 0.3595 | |
| GSE53624 | DGKD | 8527 | 125704 | 0.4924 | 0.0000 | |
| GSE63941 | DGKD | 8527 | 208072_s_at | 0.7763 | 0.0987 | |
| GSE77861 | DGKD | 8527 | 208072_s_at | 0.2461 | 0.0990 | |
| GSE97050 | DGKD | 8527 | A_23_P210253 | 0.3140 | 0.2987 | |
| SRP007169 | DGKD | 8527 | RNAseq | 2.3315 | 0.0001 | |
| SRP008496 | DGKD | 8527 | RNAseq | 3.2525 | 0.0000 | |
| SRP064894 | DGKD | 8527 | RNAseq | 0.2385 | 0.2613 | |
| SRP133303 | DGKD | 8527 | RNAseq | 0.2154 | 0.2343 | |
| SRP159526 | DGKD | 8527 | RNAseq | 0.4770 | 0.1157 | |
| SRP193095 | DGKD | 8527 | RNAseq | 0.0162 | 0.9618 | |
| SRP219564 | DGKD | 8527 | RNAseq | 0.9705 | 0.0095 | |
| TCGA | DGKD | 8527 | RNAseq | -0.8138 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DGKD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGKD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGKD | 8527 | 1 | 11 | 18 | |
| GSE20123 | DGKD | 8527 | 1 | 11 | 18 | |
| GSE43470 | DGKD | 8527 | 1 | 9 | 33 | |
| GSE46452 | DGKD | 8527 | 0 | 5 | 54 | |
| GSE47630 | DGKD | 8527 | 4 | 5 | 31 | |
| GSE54993 | DGKD | 8527 | 3 | 2 | 65 | |
| GSE54994 | DGKD | 8527 | 6 | 10 | 37 | |
| GSE60625 | DGKD | 8527 | 0 | 3 | 8 | |
| GSE74703 | DGKD | 8527 | 1 | 7 | 28 | |
| GSE74704 | DGKD | 8527 | 1 | 5 | 14 | |
| TCGA | DGKD | 8527 | 12 | 28 | 56 |
Total number of gains: 30; Total number of losses: 96; Total Number of normals: 362.
Somatic mutations of DGKD:
Generating mutation plots.
Highly correlated genes for DGKD:
Showing top 20/995 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGKD | SLC39A3 | 0.807559 | 3 | 0 | 3 |
| DGKD | CCDC127 | 0.7933 | 3 | 0 | 3 |
| DGKD | PPP1R35 | 0.775401 | 3 | 0 | 3 |
| DGKD | INTS8 | 0.764651 | 3 | 0 | 3 |
| DGKD | ABHD2 | 0.757779 | 3 | 0 | 3 |
| DGKD | MRPL36 | 0.7563 | 3 | 0 | 3 |
| DGKD | CCM2 | 0.744346 | 4 | 0 | 4 |
| DGKD | RNF139-AS1 | 0.741721 | 3 | 0 | 3 |
| DGKD | KDM4A | 0.740823 | 4 | 0 | 4 |
| DGKD | MRPL47 | 0.739927 | 3 | 0 | 3 |
| DGKD | SPTAN1 | 0.737465 | 3 | 0 | 3 |
| DGKD | SLC46A1 | 0.731079 | 3 | 0 | 3 |
| DGKD | CAMKK1 | 0.729989 | 4 | 0 | 4 |
| DGKD | UTP23 | 0.725644 | 4 | 0 | 3 |
| DGKD | MED10 | 0.725122 | 3 | 0 | 3 |
| DGKD | ZNF518B | 0.724234 | 3 | 0 | 3 |
| DGKD | CRELD2 | 0.724153 | 3 | 0 | 3 |
| DGKD | CRTC2 | 0.7197 | 4 | 0 | 3 |
| DGKD | TATDN1 | 0.719227 | 4 | 0 | 3 |
| DGKD | WDR54 | 0.718422 | 4 | 0 | 3 |
For details and further investigation, click here
