| Full name: polypeptide N-acetylgalactosaminyltransferase 6 | Alias Symbol: GalNAc-T6 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 11226 | HGNC ID: HGNC:4128 | Ensembl Gene: ENSG00000139629 | OMIM ID: 605148 |
| Drug and gene relationship at DGIdb | |||
Expression of GALNT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALNT6 | 11226 | 219956_at | 2.1096 | 0.0777 | |
| GSE20347 | GALNT6 | 11226 | 219956_at | 1.6479 | 0.0001 | |
| GSE23400 | GALNT6 | 11226 | 219956_at | 0.7127 | 0.0000 | |
| GSE26886 | GALNT6 | 11226 | 228303_at | 1.9186 | 0.0000 | |
| GSE29001 | GALNT6 | 11226 | 219956_at | 1.6277 | 0.0005 | |
| GSE38129 | GALNT6 | 11226 | 219956_at | 1.5258 | 0.0000 | |
| GSE45670 | GALNT6 | 11226 | 219956_at | 1.6458 | 0.0030 | |
| GSE53622 | GALNT6 | 11226 | 99290 | 1.6608 | 0.0000 | |
| GSE53624 | GALNT6 | 11226 | 124966 | 1.9336 | 0.0000 | |
| GSE63941 | GALNT6 | 11226 | 219956_at | 1.1031 | 0.2400 | |
| GSE77861 | GALNT6 | 11226 | 228303_at | 0.3976 | 0.1822 | |
| GSE97050 | GALNT6 | 11226 | A_33_P3215768 | 0.4720 | 0.1356 | |
| SRP007169 | GALNT6 | 11226 | RNAseq | 1.9651 | 0.0078 | |
| SRP008496 | GALNT6 | 11226 | RNAseq | 3.1976 | 0.0000 | |
| SRP064894 | GALNT6 | 11226 | RNAseq | 0.7382 | 0.1241 | |
| SRP133303 | GALNT6 | 11226 | RNAseq | 1.2083 | 0.0060 | |
| SRP159526 | GALNT6 | 11226 | RNAseq | 1.7746 | 0.0000 | |
| SRP193095 | GALNT6 | 11226 | RNAseq | -0.0760 | 0.8554 | |
| SRP219564 | GALNT6 | 11226 | RNAseq | 2.2151 | 0.0000 | |
| TCGA | GALNT6 | 11226 | RNAseq | -0.0846 | 0.6103 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by GALNT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALNT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALNT6 | 11226 | 8 | 1 | 21 | |
| GSE20123 | GALNT6 | 11226 | 8 | 1 | 21 | |
| GSE43470 | GALNT6 | 11226 | 4 | 0 | 39 | |
| GSE46452 | GALNT6 | 11226 | 8 | 1 | 50 | |
| GSE47630 | GALNT6 | 11226 | 11 | 2 | 27 | |
| GSE54993 | GALNT6 | 11226 | 0 | 5 | 65 | |
| GSE54994 | GALNT6 | 11226 | 3 | 2 | 48 | |
| GSE60625 | GALNT6 | 11226 | 0 | 0 | 11 | |
| GSE74703 | GALNT6 | 11226 | 3 | 0 | 33 | |
| GSE74704 | GALNT6 | 11226 | 5 | 1 | 14 | |
| TCGA | GALNT6 | 11226 | 14 | 11 | 71 |
Total number of gains: 64; Total number of losses: 24; Total Number of normals: 400.
Somatic mutations of GALNT6:
Generating mutation plots.
Highly correlated genes for GALNT6:
Showing top 20/1603 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALNT6 | PPP1R35 | 0.805137 | 3 | 0 | 3 |
| GALNT6 | PSAP | 0.775558 | 3 | 0 | 3 |
| GALNT6 | RLIM | 0.771919 | 3 | 0 | 3 |
| GALNT6 | RHOBTB2 | 0.75805 | 3 | 0 | 3 |
| GALNT6 | ZNF284 | 0.752978 | 3 | 0 | 3 |
| GALNT6 | DMAP1 | 0.73384 | 3 | 0 | 3 |
| GALNT6 | CCM2 | 0.73069 | 7 | 0 | 7 |
| GALNT6 | UCN2 | 0.729166 | 3 | 0 | 3 |
| GALNT6 | RAVER1 | 0.728978 | 3 | 0 | 3 |
| GALNT6 | KRTCAP2 | 0.72339 | 5 | 0 | 5 |
| GALNT6 | FAM89A | 0.717935 | 3 | 0 | 3 |
| GALNT6 | MNT | 0.712045 | 3 | 0 | 3 |
| GALNT6 | USP21 | 0.711896 | 3 | 0 | 3 |
| GALNT6 | CRYBB2 | 0.710181 | 3 | 0 | 3 |
| GALNT6 | ZNF706 | 0.708273 | 3 | 0 | 3 |
| GALNT6 | PET117 | 0.70809 | 3 | 0 | 3 |
| GALNT6 | DOCK11 | 0.705917 | 3 | 0 | 3 |
| GALNT6 | CABLES2 | 0.704001 | 3 | 0 | 3 |
| GALNT6 | SPATA17 | 0.701146 | 5 | 0 | 5 |
| GALNT6 | PDGFRB | 0.701117 | 4 | 0 | 4 |
For details and further investigation, click here
