| Full name: proline rich protein HaeIII subfamily 2 | Alias Symbol: Pr | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 5555 | HGNC ID: HGNC:9367 | Ensembl Gene: ENSG00000134551 | OMIM ID: 168790 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PRH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PRH2 | 5555 | 54067 | -0.6455 | 0.0077 | |
| GSE53624 | PRH2 | 5555 | 54067 | -1.6968 | 0.0000 | |
| GSE97050 | PRH2 | 5555 | A_23_P99076 | -1.7680 | 0.1880 | |
| SRP133303 | PRH2 | 5555 | RNAseq | -3.4598 | 0.0000 | |
| SRP193095 | PRH2 | 5555 | RNAseq | 0.2995 | 0.1398 | |
| TCGA | PRH2 | 5555 | RNAseq | 0.0190 | 0.9606 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PRH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRH2 | 5555 | 6 | 2 | 22 | |
| GSE20123 | PRH2 | 5555 | 6 | 2 | 22 | |
| GSE43470 | PRH2 | 5555 | 9 | 3 | 31 | |
| GSE46452 | PRH2 | 5555 | 10 | 1 | 48 | |
| GSE47630 | PRH2 | 5555 | 14 | 2 | 24 | |
| GSE54993 | PRH2 | 5555 | 1 | 10 | 59 | |
| GSE54994 | PRH2 | 5555 | 9 | 2 | 42 | |
| GSE60625 | PRH2 | 5555 | 0 | 1 | 10 | |
| GSE74703 | PRH2 | 5555 | 9 | 2 | 25 | |
| GSE74704 | PRH2 | 5555 | 4 | 1 | 15 | |
| TCGA | PRH2 | 5555 | 37 | 8 | 51 |
Total number of gains: 105; Total number of losses: 34; Total Number of normals: 349.
Somatic mutations of PRH2:
Generating mutation plots.
Highly correlated genes for PRH2:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRH2 | PRB4 | 0.947207 | 3 | 0 | 3 |
| PRH2 | LPO | 0.875629 | 3 | 0 | 3 |
| PRH2 | LCN1 | 0.854892 | 3 | 0 | 3 |
| PRH2 | PRB1 | 0.821011 | 3 | 0 | 3 |
| PRH2 | PRB3 | 0.813371 | 3 | 0 | 3 |
| PRH2 | SCGB3A1 | 0.804934 | 3 | 0 | 3 |
| PRH2 | MUC7 | 0.779359 | 3 | 0 | 3 |
| PRH2 | ZG16B | 0.726124 | 3 | 0 | 3 |
| PRH2 | SCGB3A2 | 0.701901 | 3 | 0 | 3 |
| PRH2 | C6orf58 | 0.658924 | 3 | 0 | 3 |
| PRH2 | RAB36 | 0.656883 | 3 | 0 | 3 |
| PRH2 | STATH | 0.652276 | 3 | 0 | 3 |
| PRH2 | BPIFB2 | 0.647947 | 3 | 0 | 3 |
| PRH2 | MSMB | 0.645945 | 3 | 0 | 3 |
| PRH2 | VWCE | 0.643108 | 3 | 0 | 3 |
| PRH2 | LRRC26 | 0.641281 | 3 | 0 | 3 |
| PRH2 | MUC5B | 0.639639 | 3 | 0 | 3 |
| PRH2 | BPIFB1 | 0.629185 | 3 | 0 | 3 |
| PRH2 | PIGR | 0.606354 | 3 | 0 | 3 |
| PRH2 | ZNF775 | 0.583724 | 3 | 0 | 3 |
For details and further investigation, click here
