| Full name: lactoperoxidase | Alias Symbol: SPO | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 4025 | HGNC ID: HGNC:6678 | Ensembl Gene: ENSG00000167419 | OMIM ID: 150205 |
| Drug and gene relationship at DGIdb | |||
Expression of LPO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LPO | 4025 | 210682_at | -0.4470 | 0.2418 | |
| GSE20347 | LPO | 4025 | 210682_at | -0.0354 | 0.6860 | |
| GSE23400 | LPO | 4025 | 210682_at | -0.1766 | 0.0000 | |
| GSE26886 | LPO | 4025 | 210682_at | -0.2855 | 0.0142 | |
| GSE29001 | LPO | 4025 | 210682_at | -0.3580 | 0.0065 | |
| GSE38129 | LPO | 4025 | 210682_at | -0.1156 | 0.1504 | |
| GSE45670 | LPO | 4025 | 210682_at | -0.0969 | 0.4767 | |
| GSE53622 | LPO | 4025 | 52815 | -0.5854 | 0.0019 | |
| GSE53624 | LPO | 4025 | 52815 | -1.2484 | 0.0000 | |
| GSE63941 | LPO | 4025 | 210682_at | 0.1983 | 0.1824 | |
| GSE77861 | LPO | 4025 | 210682_at | 0.0533 | 0.6571 | |
| GSE97050 | LPO | 4025 | A_23_P100583 | -1.0135 | 0.2566 | |
| TCGA | LPO | 4025 | RNAseq | 3.8862 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by LPO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LPO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LPO | 4025 | 5 | 1 | 24 | |
| GSE20123 | LPO | 4025 | 5 | 1 | 24 | |
| GSE43470 | LPO | 4025 | 4 | 0 | 39 | |
| GSE46452 | LPO | 4025 | 32 | 0 | 27 | |
| GSE47630 | LPO | 4025 | 7 | 1 | 32 | |
| GSE54993 | LPO | 4025 | 2 | 5 | 63 | |
| GSE54994 | LPO | 4025 | 8 | 6 | 39 | |
| GSE60625 | LPO | 4025 | 4 | 0 | 7 | |
| GSE74703 | LPO | 4025 | 4 | 0 | 32 | |
| GSE74704 | LPO | 4025 | 4 | 1 | 15 | |
| TCGA | LPO | 4025 | 26 | 8 | 62 |
Total number of gains: 101; Total number of losses: 23; Total Number of normals: 364.
Somatic mutations of LPO:
Generating mutation plots.
Highly correlated genes for LPO:
Showing top 20/438 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LPO | PRH2 | 0.875629 | 3 | 0 | 3 |
| LPO | PRB4 | 0.707312 | 9 | 0 | 8 |
| LPO | SCGB1D2 | 0.680097 | 7 | 0 | 7 |
| LPO | MAB21L2 | 0.676227 | 3 | 0 | 3 |
| LPO | KNG1 | 0.671649 | 3 | 0 | 3 |
| LPO | PRB1 | 0.663676 | 8 | 0 | 8 |
| LPO | SCGB3A2 | 0.662592 | 5 | 0 | 5 |
| LPO | ANGPT4 | 0.661552 | 5 | 0 | 5 |
| LPO | FSCN3 | 0.660487 | 3 | 0 | 3 |
| LPO | OPN1SW | 0.660453 | 3 | 0 | 3 |
| LPO | C6orf58 | 0.659725 | 5 | 0 | 5 |
| LPO | SPX | 0.65924 | 4 | 0 | 3 |
| LPO | P2RX6 | 0.654627 | 4 | 0 | 4 |
| LPO | HHLA1 | 0.646819 | 4 | 0 | 4 |
| LPO | LRRC26 | 0.64572 | 3 | 0 | 3 |
| LPO | ZG16B | 0.644407 | 6 | 0 | 5 |
| LPO | OR1A1 | 0.643934 | 4 | 0 | 4 |
| LPO | LCN1 | 0.643097 | 9 | 0 | 5 |
| LPO | PIP | 0.638581 | 9 | 0 | 7 |
| LPO | SNX11 | 0.638216 | 3 | 0 | 3 |
For details and further investigation, click here
