| Full name: microseminoprotein beta | Alias Symbol: PSP-94|PSP57|PSP94|IGBF|MSP|MSPB|PN44|PRPS|PSP | ||
| Type: protein-coding gene | Cytoband: 10q11.22 | ||
| Entrez ID: 4477 | HGNC ID: HGNC:7372 | Ensembl Gene: ENSG00000263639 | OMIM ID: 157145 |
| Drug and gene relationship at DGIdb | |||
Expression of MSMB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MSMB | 4477 | 210297_s_at | -0.6964 | 0.7296 | |
| GSE20347 | MSMB | 4477 | 210297_s_at | 0.2033 | 0.1494 | |
| GSE23400 | MSMB | 4477 | 210297_s_at | -0.3795 | 0.0055 | |
| GSE26886 | MSMB | 4477 | 210297_s_at | 1.0190 | 0.0014 | |
| GSE29001 | MSMB | 4477 | 210297_s_at | 0.3081 | 0.3040 | |
| GSE38129 | MSMB | 4477 | 210297_s_at | 0.1246 | 0.6692 | |
| GSE45670 | MSMB | 4477 | 210297_s_at | -1.1144 | 0.2422 | |
| GSE53622 | MSMB | 4477 | 6501 | -1.2007 | 0.0174 | |
| GSE53624 | MSMB | 4477 | 6501 | -1.5622 | 0.0000 | |
| GSE63941 | MSMB | 4477 | 210297_s_at | 0.4918 | 0.4171 | |
| GSE77861 | MSMB | 4477 | 210297_s_at | 0.4488 | 0.4000 | |
| GSE97050 | MSMB | 4477 | A_24_P146683 | -0.4731 | 0.2171 | |
| SRP133303 | MSMB | 4477 | RNAseq | -5.2812 | 0.0000 | |
| TCGA | MSMB | 4477 | RNAseq | -1.5615 | 0.0183 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by MSMB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MSMB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MSMB | 4477 | 2 | 5 | 23 | |
| GSE20123 | MSMB | 4477 | 2 | 5 | 23 | |
| GSE43470 | MSMB | 4477 | 2 | 6 | 35 | |
| GSE46452 | MSMB | 4477 | 0 | 13 | 46 | |
| GSE47630 | MSMB | 4477 | 4 | 12 | 24 | |
| GSE54993 | MSMB | 4477 | 9 | 0 | 61 | |
| GSE54994 | MSMB | 4477 | 2 | 10 | 41 | |
| GSE60625 | MSMB | 4477 | 0 | 0 | 11 | |
| GSE74703 | MSMB | 4477 | 2 | 3 | 31 | |
| GSE74704 | MSMB | 4477 | 1 | 4 | 15 | |
| TCGA | MSMB | 4477 | 13 | 22 | 61 |
Total number of gains: 37; Total number of losses: 80; Total Number of normals: 371.
Somatic mutations of MSMB:
Generating mutation plots.
Highly correlated genes for MSMB:
Showing top 20/42 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MSMB | LRRC26 | 0.730359 | 3 | 0 | 3 |
| MSMB | ZG16B | 0.722319 | 6 | 0 | 5 |
| MSMB | C6orf58 | 0.706535 | 5 | 0 | 5 |
| MSMB | LGALS9 | 0.679874 | 3 | 0 | 3 |
| MSMB | BPIFB1 | 0.679183 | 5 | 0 | 5 |
| MSMB | POU2F3 | 0.672961 | 3 | 0 | 3 |
| MSMB | GLYATL2 | 0.67048 | 3 | 0 | 3 |
| MSMB | SCGB2A2 | 0.654711 | 4 | 0 | 4 |
| MSMB | TFF1 | 0.649043 | 7 | 0 | 7 |
| MSMB | PRH2 | 0.645945 | 3 | 0 | 3 |
| MSMB | AZGP1 | 0.641956 | 8 | 0 | 7 |
| MSMB | MUC7 | 0.636728 | 4 | 0 | 3 |
| MSMB | PAX6 | 0.623259 | 3 | 0 | 3 |
| MSMB | ATOH7 | 0.599619 | 3 | 0 | 3 |
| MSMB | SCGB3A2 | 0.598092 | 4 | 0 | 3 |
| MSMB | KIAA1324 | 0.592527 | 8 | 0 | 6 |
| MSMB | AGR2 | 0.590501 | 10 | 0 | 8 |
| MSMB | NXPE4 | 0.585714 | 5 | 0 | 3 |
| MSMB | UGT8 | 0.58367 | 3 | 0 | 3 |
| MSMB | TFF2 | 0.573367 | 7 | 0 | 5 |
For details and further investigation, click here
