| Full name: polymeric immunoglobulin receptor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 5284 | HGNC ID: HGNC:8968 | Ensembl Gene: ENSG00000162896 | OMIM ID: 173880 |
| Drug and gene relationship at DGIdb | |||
Expression of PIGR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIGR | 5284 | 226147_s_at | -3.1103 | 0.2638 | |
| GSE20347 | PIGR | 5284 | 204213_at | -0.0811 | 0.4544 | |
| GSE23400 | PIGR | 5284 | 204213_at | -0.1664 | 0.0000 | |
| GSE26886 | PIGR | 5284 | 204213_at | -0.1057 | 0.5579 | |
| GSE29001 | PIGR | 5284 | 204213_at | -0.3335 | 0.0204 | |
| GSE38129 | PIGR | 5284 | 204213_at | -0.1846 | 0.0214 | |
| GSE45670 | PIGR | 5284 | 204213_at | 0.0150 | 0.9074 | |
| GSE53622 | PIGR | 5284 | 41746 | -2.7167 | 0.0000 | |
| GSE53624 | PIGR | 5284 | 41746 | -2.8709 | 0.0000 | |
| GSE77861 | PIGR | 5284 | 204213_at | -0.1000 | 0.4471 | |
| GSE97050 | PIGR | 5284 | A_24_P844984 | -0.8253 | 0.2017 | |
| SRP064894 | PIGR | 5284 | RNAseq | -3.0456 | 0.0000 | |
| SRP133303 | PIGR | 5284 | RNAseq | -5.2183 | 0.0000 | |
| SRP159526 | PIGR | 5284 | RNAseq | -1.9392 | 0.3009 | |
| SRP193095 | PIGR | 5284 | RNAseq | -3.7333 | 0.0001 | |
| SRP219564 | PIGR | 5284 | RNAseq | -2.3255 | 0.0849 | |
| TCGA | PIGR | 5284 | RNAseq | -1.8173 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by PIGR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIGR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIGR | 5284 | 11 | 0 | 19 | |
| GSE20123 | PIGR | 5284 | 11 | 0 | 19 | |
| GSE43470 | PIGR | 5284 | 7 | 0 | 36 | |
| GSE46452 | PIGR | 5284 | 3 | 1 | 55 | |
| GSE47630 | PIGR | 5284 | 14 | 0 | 26 | |
| GSE54993 | PIGR | 5284 | 0 | 6 | 64 | |
| GSE54994 | PIGR | 5284 | 14 | 0 | 39 | |
| GSE60625 | PIGR | 5284 | 0 | 0 | 11 | |
| GSE74703 | PIGR | 5284 | 7 | 0 | 29 | |
| GSE74704 | PIGR | 5284 | 5 | 0 | 15 | |
| TCGA | PIGR | 5284 | 45 | 3 | 48 |
Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.
Somatic mutations of PIGR:
Generating mutation plots.
Highly correlated genes for PIGR:
Showing top 20/412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIGR | C6orf58 | 0.878666 | 4 | 0 | 4 |
| PIGR | ZG16B | 0.848701 | 4 | 0 | 4 |
| PIGR | BPIFB1 | 0.81942 | 5 | 0 | 4 |
| PIGR | SCGB3A1 | 0.766206 | 6 | 0 | 6 |
| PIGR | LRRC26 | 0.765256 | 3 | 0 | 3 |
| PIGR | BPIFB2 | 0.750646 | 6 | 0 | 5 |
| PIGR | KIAA1324 | 0.713446 | 4 | 0 | 4 |
| PIGR | AZGP1 | 0.70526 | 6 | 0 | 5 |
| PIGR | FMO3 | 0.682182 | 3 | 0 | 3 |
| PIGR | CYP4F2 | 0.671515 | 3 | 0 | 3 |
| PIGR | MUC5B | 0.659072 | 9 | 0 | 7 |
| PIGR | CCL28 | 0.653941 | 4 | 0 | 3 |
| PIGR | ETV2 | 0.643124 | 4 | 0 | 3 |
| PIGR | TMEM106A | 0.643059 | 3 | 0 | 3 |
| PIGR | RORC | 0.64125 | 8 | 0 | 7 |
| PIGR | CHRM1 | 0.634261 | 3 | 0 | 3 |
| PIGR | TFF1 | 0.630413 | 5 | 0 | 4 |
| PIGR | CNTFR | 0.630302 | 6 | 0 | 4 |
| PIGR | TRPV6 | 0.627833 | 3 | 0 | 3 |
| PIGR | TCN1 | 0.62658 | 5 | 0 | 4 |
For details and further investigation, click here
