| Full name: beta-1,3-glucuronyltransferase 3 | Alias Symbol: GlcAT-I | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 26229 | HGNC ID: HGNC:923 | Ensembl Gene: ENSG00000149541 | OMIM ID: 606374 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of B3GAT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B3GAT3 | 26229 | 203452_at | 0.5206 | 0.2250 | |
| GSE20347 | B3GAT3 | 26229 | 203452_at | 0.5497 | 0.0000 | |
| GSE23400 | B3GAT3 | 26229 | 203452_at | 0.2809 | 0.0000 | |
| GSE26886 | B3GAT3 | 26229 | 203452_at | 0.5575 | 0.0039 | |
| GSE29001 | B3GAT3 | 26229 | 203452_at | 0.1816 | 0.2355 | |
| GSE38129 | B3GAT3 | 26229 | 203452_at | 0.5314 | 0.0000 | |
| GSE45670 | B3GAT3 | 26229 | 203452_at | 0.4177 | 0.0001 | |
| GSE53622 | B3GAT3 | 26229 | 8604 | -0.2461 | 0.0004 | |
| GSE53624 | B3GAT3 | 26229 | 8604 | 0.0169 | 0.7774 | |
| GSE63941 | B3GAT3 | 26229 | 203452_at | 0.1945 | 0.6388 | |
| GSE77861 | B3GAT3 | 26229 | 203452_at | 0.2819 | 0.1557 | |
| GSE97050 | B3GAT3 | 26229 | A_33_P3225685 | 0.0095 | 0.9703 | |
| SRP007169 | B3GAT3 | 26229 | RNAseq | 0.8060 | 0.0733 | |
| SRP008496 | B3GAT3 | 26229 | RNAseq | 0.8468 | 0.0036 | |
| SRP064894 | B3GAT3 | 26229 | RNAseq | 0.9128 | 0.0016 | |
| SRP133303 | B3GAT3 | 26229 | RNAseq | 0.5336 | 0.0068 | |
| SRP159526 | B3GAT3 | 26229 | RNAseq | 0.7896 | 0.0129 | |
| SRP193095 | B3GAT3 | 26229 | RNAseq | 0.7304 | 0.0000 | |
| SRP219564 | B3GAT3 | 26229 | RNAseq | 0.5954 | 0.1482 | |
| TCGA | B3GAT3 | 26229 | RNAseq | 0.2028 | 0.0022 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by B3GAT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B3GAT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B3GAT3 | 26229 | 6 | 5 | 19 | |
| GSE20123 | B3GAT3 | 26229 | 6 | 5 | 19 | |
| GSE43470 | B3GAT3 | 26229 | 1 | 6 | 36 | |
| GSE46452 | B3GAT3 | 26229 | 8 | 4 | 47 | |
| GSE47630 | B3GAT3 | 26229 | 3 | 7 | 30 | |
| GSE54993 | B3GAT3 | 26229 | 3 | 0 | 67 | |
| GSE54994 | B3GAT3 | 26229 | 4 | 5 | 44 | |
| GSE60625 | B3GAT3 | 26229 | 0 | 3 | 8 | |
| GSE74703 | B3GAT3 | 26229 | 1 | 3 | 32 | |
| GSE74704 | B3GAT3 | 26229 | 4 | 3 | 13 | |
| TCGA | B3GAT3 | 26229 | 14 | 11 | 71 |
Total number of gains: 50; Total number of losses: 52; Total Number of normals: 386.
Somatic mutations of B3GAT3:
Generating mutation plots.
Highly correlated genes for B3GAT3:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B3GAT3 | GRK4 | 0.797095 | 3 | 0 | 3 |
| B3GAT3 | LYL1 | 0.766966 | 4 | 0 | 4 |
| B3GAT3 | PGP | 0.754811 | 4 | 0 | 4 |
| B3GAT3 | LAT | 0.743837 | 3 | 0 | 3 |
| B3GAT3 | ORM1 | 0.731536 | 3 | 0 | 3 |
| B3GAT3 | PRODH2 | 0.717807 | 3 | 0 | 3 |
| B3GAT3 | ZNF777 | 0.699305 | 3 | 0 | 3 |
| B3GAT3 | TCP10 | 0.690814 | 3 | 0 | 3 |
| B3GAT3 | KLK2 | 0.687854 | 4 | 0 | 3 |
| B3GAT3 | HIVEP2 | 0.683319 | 3 | 0 | 3 |
| B3GAT3 | ASNS | 0.681321 | 4 | 0 | 4 |
| B3GAT3 | FFAR2 | 0.677875 | 3 | 0 | 3 |
| B3GAT3 | LHX4-AS1 | 0.676625 | 3 | 0 | 3 |
| B3GAT3 | LRRIQ3 | 0.676544 | 3 | 0 | 3 |
| B3GAT3 | EMID1 | 0.673433 | 3 | 0 | 3 |
| B3GAT3 | SNAI1 | 0.662622 | 3 | 0 | 3 |
| B3GAT3 | MATK | 0.660922 | 4 | 0 | 3 |
| B3GAT3 | RHPN1 | 0.659485 | 3 | 0 | 3 |
| B3GAT3 | FBXL15 | 0.652618 | 4 | 0 | 3 |
| B3GAT3 | BEND3 | 0.651858 | 4 | 0 | 3 |
For details and further investigation, click here
