| Full name: pre-mRNA processing factor 39 | Alias Symbol: FLJ20666|FLJ11128 | ||
| Type: protein-coding gene | Cytoband: 14q21.2 | ||
| Entrez ID: 55015 | HGNC ID: HGNC:20314 | Ensembl Gene: ENSG00000185246 | OMIM ID: 614907 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PRPF39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPF39 | 55015 | 220553_s_at | 0.1512 | 0.8295 | |
| GSE20347 | PRPF39 | 55015 | 220553_s_at | 0.1934 | 0.2303 | |
| GSE23400 | PRPF39 | 55015 | 220553_s_at | 0.3842 | 0.0000 | |
| GSE26886 | PRPF39 | 55015 | 220553_s_at | -0.9653 | 0.0084 | |
| GSE29001 | PRPF39 | 55015 | 220553_s_at | 0.4734 | 0.0715 | |
| GSE38129 | PRPF39 | 55015 | 220553_s_at | 0.1579 | 0.2063 | |
| GSE45670 | PRPF39 | 55015 | 220553_s_at | 0.2468 | 0.0341 | |
| GSE53622 | PRPF39 | 55015 | 43301 | 0.4342 | 0.0000 | |
| GSE53624 | PRPF39 | 55015 | 43301 | 0.2049 | 0.0015 | |
| GSE63941 | PRPF39 | 55015 | 220553_s_at | -0.7181 | 0.0983 | |
| GSE77861 | PRPF39 | 55015 | 220553_s_at | 0.2784 | 0.5510 | |
| GSE97050 | PRPF39 | 55015 | A_23_P163113 | 0.1489 | 0.4467 | |
| SRP007169 | PRPF39 | 55015 | RNAseq | 0.3258 | 0.4908 | |
| SRP008496 | PRPF39 | 55015 | RNAseq | 0.4442 | 0.1167 | |
| SRP064894 | PRPF39 | 55015 | RNAseq | 0.1193 | 0.5916 | |
| SRP133303 | PRPF39 | 55015 | RNAseq | 0.1974 | 0.2247 | |
| SRP159526 | PRPF39 | 55015 | RNAseq | -0.1723 | 0.5725 | |
| SRP193095 | PRPF39 | 55015 | RNAseq | -0.0381 | 0.7003 | |
| SRP219564 | PRPF39 | 55015 | RNAseq | 0.3269 | 0.4577 | |
| TCGA | PRPF39 | 55015 | RNAseq | -0.0075 | 0.8876 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRPF39 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPF39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPF39 | 55015 | 6 | 5 | 19 | |
| GSE20123 | PRPF39 | 55015 | 6 | 5 | 19 | |
| GSE43470 | PRPF39 | 55015 | 8 | 3 | 32 | |
| GSE46452 | PRPF39 | 55015 | 17 | 2 | 40 | |
| GSE47630 | PRPF39 | 55015 | 11 | 10 | 19 | |
| GSE54993 | PRPF39 | 55015 | 3 | 9 | 58 | |
| GSE54994 | PRPF39 | 55015 | 18 | 5 | 30 | |
| GSE60625 | PRPF39 | 55015 | 0 | 2 | 9 | |
| GSE74703 | PRPF39 | 55015 | 7 | 3 | 26 | |
| GSE74704 | PRPF39 | 55015 | 3 | 3 | 14 | |
| TCGA | PRPF39 | 55015 | 31 | 15 | 50 |
Total number of gains: 110; Total number of losses: 62; Total Number of normals: 316.
Somatic mutations of PRPF39:
Generating mutation plots.
Highly correlated genes for PRPF39:
Showing top 20/218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPF39 | SREK1 | 0.708356 | 6 | 0 | 6 |
| PRPF39 | DPY19L3 | 0.66108 | 3 | 0 | 3 |
| PRPF39 | ZNF217 | 0.649983 | 4 | 0 | 4 |
| PRPF39 | ZNF544 | 0.645581 | 4 | 0 | 3 |
| PRPF39 | KDM7A | 0.641497 | 3 | 0 | 3 |
| PRPF39 | ANKRD28 | 0.636845 | 3 | 0 | 3 |
| PRPF39 | SNRNP200 | 0.628638 | 7 | 0 | 5 |
| PRPF39 | AASDH | 0.627967 | 4 | 0 | 3 |
| PRPF39 | HIRA | 0.624816 | 3 | 0 | 3 |
| PRPF39 | SFSWAP | 0.622835 | 3 | 0 | 3 |
| PRPF39 | RPL36A | 0.621126 | 3 | 0 | 3 |
| PRPF39 | MYSM1 | 0.620908 | 6 | 0 | 5 |
| PRPF39 | EPC1 | 0.619054 | 3 | 0 | 3 |
| PRPF39 | BOD1L1 | 0.616492 | 4 | 0 | 3 |
| PRPF39 | PKNOX1 | 0.616171 | 3 | 0 | 3 |
| PRPF39 | CEP76 | 0.615284 | 3 | 0 | 3 |
| PRPF39 | COCH | 0.615258 | 4 | 0 | 3 |
| PRPF39 | NUDT15 | 0.610545 | 4 | 0 | 3 |
| PRPF39 | STYX | 0.610338 | 5 | 0 | 4 |
| PRPF39 | MRFAP1L1 | 0.606659 | 3 | 0 | 3 |
For details and further investigation, click here
