| Full name: zinc finger protein 217 | Alias Symbol: ZABC1 | ||
| Type: protein-coding gene | Cytoband: 20q13.2 | ||
| Entrez ID: 7764 | HGNC ID: HGNC:13009 | Ensembl Gene: ENSG00000171940 | OMIM ID: 602967 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNF217:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF217 | 7764 | 203739_at | 0.3234 | 0.6397 | |
| GSE20347 | ZNF217 | 7764 | 203739_at | 0.1267 | 0.4426 | |
| GSE23400 | ZNF217 | 7764 | 203739_at | 0.4182 | 0.0001 | |
| GSE26886 | ZNF217 | 7764 | 203739_at | -1.0341 | 0.0024 | |
| GSE29001 | ZNF217 | 7764 | 203739_at | 0.0920 | 0.6845 | |
| GSE38129 | ZNF217 | 7764 | 203739_at | 0.3476 | 0.0320 | |
| GSE45670 | ZNF217 | 7764 | 203739_at | 0.2043 | 0.3521 | |
| GSE53622 | ZNF217 | 7764 | 27275 | 0.4167 | 0.0000 | |
| GSE53624 | ZNF217 | 7764 | 27275 | 0.2281 | 0.0003 | |
| GSE63941 | ZNF217 | 7764 | 203739_at | -1.0424 | 0.0860 | |
| GSE77861 | ZNF217 | 7764 | 203739_at | 0.6539 | 0.0439 | |
| GSE97050 | ZNF217 | 7764 | A_33_P3272773 | -0.0301 | 0.9448 | |
| SRP007169 | ZNF217 | 7764 | RNAseq | 0.2445 | 0.5414 | |
| SRP008496 | ZNF217 | 7764 | RNAseq | 0.1221 | 0.6364 | |
| SRP064894 | ZNF217 | 7764 | RNAseq | 0.0081 | 0.9785 | |
| SRP133303 | ZNF217 | 7764 | RNAseq | 0.2179 | 0.1591 | |
| SRP159526 | ZNF217 | 7764 | RNAseq | 0.2675 | 0.2634 | |
| SRP193095 | ZNF217 | 7764 | RNAseq | 0.1607 | 0.1529 | |
| SRP219564 | ZNF217 | 7764 | RNAseq | -0.5241 | 0.2935 | |
| TCGA | ZNF217 | 7764 | RNAseq | 0.1368 | 0.0061 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF217 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF217:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF217 | 7764 | 17 | 2 | 11 | |
| GSE20123 | ZNF217 | 7764 | 17 | 2 | 11 | |
| GSE43470 | ZNF217 | 7764 | 14 | 0 | 29 | |
| GSE46452 | ZNF217 | 7764 | 29 | 0 | 30 | |
| GSE47630 | ZNF217 | 7764 | 24 | 1 | 15 | |
| GSE54993 | ZNF217 | 7764 | 0 | 17 | 53 | |
| GSE54994 | ZNF217 | 7764 | 27 | 0 | 26 | |
| GSE60625 | ZNF217 | 7764 | 0 | 0 | 11 | |
| GSE74703 | ZNF217 | 7764 | 11 | 0 | 25 | |
| GSE74704 | ZNF217 | 7764 | 13 | 0 | 7 | |
| TCGA | ZNF217 | 7764 | 45 | 3 | 48 |
Total number of gains: 197; Total number of losses: 25; Total Number of normals: 266.
Somatic mutations of ZNF217:
Generating mutation plots.
Highly correlated genes for ZNF217:
Showing top 20/407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF217 | NAA20 | 0.86007 | 3 | 0 | 3 |
| ZNF217 | DPY19L3 | 0.82159 | 3 | 0 | 3 |
| ZNF217 | STX3 | 0.802956 | 3 | 0 | 3 |
| ZNF217 | TMED2 | 0.755371 | 4 | 0 | 4 |
| ZNF217 | IRAK4 | 0.753429 | 3 | 0 | 3 |
| ZNF217 | ATP6V1B2 | 0.748573 | 3 | 0 | 3 |
| ZNF217 | MYSM1 | 0.741461 | 3 | 0 | 3 |
| ZNF217 | ATP6V0D1 | 0.734836 | 3 | 0 | 3 |
| ZNF217 | SERPINB9 | 0.730789 | 3 | 0 | 3 |
| ZNF217 | C18orf54 | 0.730493 | 3 | 0 | 3 |
| ZNF217 | IBTK | 0.728238 | 3 | 0 | 3 |
| ZNF217 | SIKE1 | 0.727857 | 3 | 0 | 3 |
| ZNF217 | GTF2A1 | 0.725396 | 3 | 0 | 3 |
| ZNF217 | HAS3 | 0.723334 | 4 | 0 | 4 |
| ZNF217 | RIOK2 | 0.711633 | 3 | 0 | 3 |
| ZNF217 | MSL2 | 0.711465 | 4 | 0 | 3 |
| ZNF217 | FAM126B | 0.708556 | 4 | 0 | 4 |
| ZNF217 | ZFX | 0.70727 | 3 | 0 | 3 |
| ZNF217 | MTPN | 0.706955 | 3 | 0 | 3 |
| ZNF217 | METAP1 | 0.706023 | 5 | 0 | 5 |
For details and further investigation, click here
