| Full name: serine/threonine/tyrosine interacting protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q22.1 | ||
| Entrez ID: 6815 | HGNC ID: HGNC:11447 | Ensembl Gene: ENSG00000198252 | OMIM ID: 615814 |
| Drug and gene relationship at DGIdb | |||
Expression of STYX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STYX | 6815 | 228853_at | 0.2007 | 0.7421 | |
| GSE26886 | STYX | 6815 | 228853_at | -0.4961 | 0.0435 | |
| GSE45670 | STYX | 6815 | 228853_at | -0.0750 | 0.6087 | |
| GSE53622 | STYX | 6815 | 133156 | -0.1755 | 0.0385 | |
| GSE53624 | STYX | 6815 | 133156 | -0.1149 | 0.2687 | |
| GSE63941 | STYX | 6815 | 228853_at | -0.4259 | 0.3468 | |
| GSE77861 | STYX | 6815 | 228853_at | -0.2442 | 0.4676 | |
| GSE97050 | STYX | 6815 | A_32_P109794 | 0.2689 | 0.4774 | |
| SRP007169 | STYX | 6815 | RNAseq | -0.0037 | 0.9908 | |
| SRP008496 | STYX | 6815 | RNAseq | 0.0032 | 0.9913 | |
| SRP064894 | STYX | 6815 | RNAseq | 0.1174 | 0.4314 | |
| SRP133303 | STYX | 6815 | RNAseq | 0.2299 | 0.2352 | |
| SRP159526 | STYX | 6815 | RNAseq | -0.2418 | 0.3908 | |
| SRP193095 | STYX | 6815 | RNAseq | -0.3143 | 0.0067 | |
| SRP219564 | STYX | 6815 | RNAseq | -0.0193 | 0.9503 | |
| TCGA | STYX | 6815 | RNAseq | -0.0038 | 0.9463 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STYX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STYX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STYX | 6815 | 8 | 3 | 19 | |
| GSE20123 | STYX | 6815 | 8 | 3 | 19 | |
| GSE43470 | STYX | 6815 | 9 | 1 | 33 | |
| GSE46452 | STYX | 6815 | 16 | 3 | 40 | |
| GSE47630 | STYX | 6815 | 11 | 10 | 19 | |
| GSE54993 | STYX | 6815 | 3 | 8 | 59 | |
| GSE54994 | STYX | 6815 | 19 | 4 | 30 | |
| GSE60625 | STYX | 6815 | 0 | 2 | 9 | |
| GSE74703 | STYX | 6815 | 8 | 1 | 27 | |
| GSE74704 | STYX | 6815 | 3 | 2 | 15 | |
| TCGA | STYX | 6815 | 34 | 12 | 50 |
Total number of gains: 119; Total number of losses: 49; Total Number of normals: 320.
Somatic mutations of STYX:
Generating mutation plots.
Highly correlated genes for STYX:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STYX | EXOC8 | 0.793643 | 3 | 0 | 3 |
| STYX | ZBTB11 | 0.787008 | 3 | 0 | 3 |
| STYX | TMEM69 | 0.782062 | 3 | 0 | 3 |
| STYX | EBAG9 | 0.778099 | 3 | 0 | 3 |
| STYX | SLC25A30 | 0.774498 | 3 | 0 | 3 |
| STYX | MRPS22 | 0.769525 | 3 | 0 | 3 |
| STYX | C2orf76 | 0.76525 | 3 | 0 | 3 |
| STYX | RRAGC | 0.75433 | 3 | 0 | 3 |
| STYX | RNF144B | 0.753551 | 4 | 0 | 4 |
| STYX | PPP4R2 | 0.745126 | 3 | 0 | 3 |
| STYX | CRIM1 | 0.732972 | 3 | 0 | 3 |
| STYX | BRWD1 | 0.729 | 3 | 0 | 3 |
| STYX | WDR82 | 0.72684 | 3 | 0 | 3 |
| STYX | ALKBH3 | 0.721455 | 3 | 0 | 3 |
| STYX | ZNF146 | 0.721101 | 3 | 0 | 3 |
| STYX | FARS2 | 0.720208 | 3 | 0 | 3 |
| STYX | EIF5B | 0.720043 | 4 | 0 | 3 |
| STYX | MTMR2 | 0.719279 | 3 | 0 | 3 |
| STYX | NR2C1 | 0.718217 | 3 | 0 | 3 |
| STYX | CSNK1G3 | 0.715267 | 3 | 0 | 3 |
For details and further investigation, click here
