| Full name: lysine demethylase 7A | Alias Symbol: KIAA1718 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 80853 | HGNC ID: HGNC:22224 | Ensembl Gene: ENSG00000006459 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KDM7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KDM7A | 80853 | 221778_at | 0.0233 | 0.9830 | |
| GSE20347 | KDM7A | 80853 | 221778_at | -0.2517 | 0.2305 | |
| GSE23400 | KDM7A | 80853 | 221778_at | -0.0774 | 0.4369 | |
| GSE26886 | KDM7A | 80853 | 221778_at | -1.6672 | 0.0001 | |
| GSE29001 | KDM7A | 80853 | 221778_at | -0.3388 | 0.2969 | |
| GSE38129 | KDM7A | 80853 | 221778_at | -0.0973 | 0.5781 | |
| GSE45670 | KDM7A | 80853 | 221778_at | 0.0630 | 0.7786 | |
| GSE53622 | KDM7A | 80853 | 2684 | -0.0533 | 0.6441 | |
| GSE53624 | KDM7A | 80853 | 113639 | -0.4421 | 0.0000 | |
| GSE63941 | KDM7A | 80853 | 221778_at | -1.9287 | 0.0047 | |
| GSE77861 | KDM7A | 80853 | 221778_at | 0.8197 | 0.0152 | |
| SRP007169 | KDM7A | 80853 | RNAseq | 0.4566 | 0.2064 | |
| SRP008496 | KDM7A | 80853 | RNAseq | 0.2768 | 0.3134 | |
| SRP064894 | KDM7A | 80853 | RNAseq | -0.3191 | 0.3692 | |
| SRP133303 | KDM7A | 80853 | RNAseq | -0.0135 | 0.9530 | |
| SRP159526 | KDM7A | 80853 | RNAseq | -0.7420 | 0.1860 | |
| SRP193095 | KDM7A | 80853 | RNAseq | -0.1813 | 0.1398 | |
| SRP219564 | KDM7A | 80853 | RNAseq | -1.1814 | 0.0265 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by KDM7A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KDM7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KDM7A | 80853 | 5 | 2 | 23 | |
| GSE20123 | KDM7A | 80853 | 5 | 2 | 23 | |
| GSE43470 | KDM7A | 80853 | 2 | 4 | 37 | |
| GSE46452 | KDM7A | 80853 | 7 | 2 | 50 | |
| GSE47630 | KDM7A | 80853 | 7 | 4 | 29 | |
| GSE54993 | KDM7A | 80853 | 3 | 5 | 62 | |
| GSE54994 | KDM7A | 80853 | 5 | 8 | 40 | |
| GSE60625 | KDM7A | 80853 | 0 | 0 | 11 | |
| GSE74703 | KDM7A | 80853 | 2 | 4 | 30 | |
| GSE74704 | KDM7A | 80853 | 1 | 2 | 17 |
Total number of gains: 37; Total number of losses: 33; Total Number of normals: 322.
Somatic mutations of KDM7A:
Generating mutation plots.
Highly correlated genes for KDM7A:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KDM7A | LMTK2 | 0.738234 | 3 | 0 | 3 |
| KDM7A | EXOC4 | 0.69522 | 3 | 0 | 3 |
| KDM7A | SLC37A3 | 0.678873 | 4 | 0 | 4 |
| KDM7A | PRPF39 | 0.641497 | 3 | 0 | 3 |
| KDM7A | ZC3HAV1L | 0.60549 | 4 | 0 | 3 |
| KDM7A | SHOC2 | 0.601408 | 5 | 0 | 3 |
| KDM7A | ZNF217 | 0.594194 | 6 | 0 | 5 |
| KDM7A | UBE2H | 0.592492 | 6 | 0 | 5 |
| KDM7A | UBE3A | 0.592127 | 3 | 0 | 3 |
| KDM7A | TMEM87B | 0.588301 | 4 | 0 | 4 |
| KDM7A | TRIP12 | 0.587907 | 3 | 0 | 3 |
| KDM7A | CCDC117 | 0.587567 | 3 | 0 | 3 |
| KDM7A | CMTR2 | 0.585488 | 3 | 0 | 3 |
| KDM7A | DTWD1 | 0.585196 | 3 | 0 | 3 |
| KDM7A | ILKAP | 0.583816 | 3 | 0 | 3 |
| KDM7A | TMEM209 | 0.582808 | 3 | 0 | 3 |
| KDM7A | SLC35B4 | 0.582467 | 4 | 0 | 3 |
| KDM7A | AGK | 0.582063 | 4 | 0 | 3 |
| KDM7A | ARF5 | 0.581852 | 5 | 0 | 3 |
| KDM7A | MKRN1 | 0.581656 | 6 | 0 | 4 |
For details and further investigation, click here
