NUDT15

 

Full name: nudix hydrolase 15 Alias Symbol: MTH2|FLJ10956
Type: protein-coding gene Cytoband: 13q14.2
Entrez ID: 55270 HGNC ID: HGNC:23063 Ensembl Gene: ENSG00000136159 OMIM ID: 615792
Drug and gene relationship at DGIdb

 

Expression of NUDT15:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUDT15 55270 219347_at 0.2632 0.6907
GSE20347 NUDT15 55270 219347_at 0.0508 0.8111
GSE23400 NUDT15 55270 219347_at 0.4445 0.0000
GSE26886 NUDT15 55270 219347_at 0.5688 0.0137
GSE29001 NUDT15 55270 219347_at 0.2232 0.4433
GSE38129 NUDT15 55270 219347_at 0.3767 0.0498
GSE45670 NUDT15 55270 219347_at 0.4058 0.0038
GSE53622 NUDT15 55270 12563 0.2971 0.0026
GSE53624 NUDT15 55270 12563 0.2789 0.0402
GSE63941 NUDT15 55270 219347_at 0.1560 0.7893
GSE77861 NUDT15 55270 219347_at 0.2243 0.4671
GSE97050 NUDT15 55270 A_24_P244699 0.5130 0.1585
SRP007169 NUDT15 55270 RNAseq 0.2763 0.6016
SRP008496 NUDT15 55270 RNAseq 0.3285 0.3534
SRP064894 NUDT15 55270 RNAseq 0.3654 0.0824
SRP133303 NUDT15 55270 RNAseq -0.0106 0.9362
SRP159526 NUDT15 55270 RNAseq -0.1608 0.4276
SRP193095 NUDT15 55270 RNAseq -0.1004 0.5251
SRP219564 NUDT15 55270 RNAseq 0.1278 0.6985
TCGA NUDT15 55270 RNAseq 0.2714 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by NUDT15 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NUDT15:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUDT15 55270 0 13 17
GSE20123 NUDT15 55270 0 12 18
GSE43470 NUDT15 55270 3 13 27
GSE46452 NUDT15 55270 0 32 27
GSE47630 NUDT15 55270 2 27 11
GSE54993 NUDT15 55270 12 2 56
GSE54994 NUDT15 55270 1 17 35
GSE60625 NUDT15 55270 0 3 8
GSE74703 NUDT15 55270 3 10 23
GSE74704 NUDT15 55270 0 9 11
TCGA NUDT15 55270 8 38 50

Total number of gains: 29; Total number of losses: 176; Total Number of normals: 283.  

 

Somatic mutations of NUDT15:

 

Generating mutation plots.

 

Highly correlated genes for NUDT15:

 

Showing top 20/888 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUDT15RAD170.829932303
NUDT15TM9SF10.797009303
NUDT15DDHD10.774607303
NUDT15RAB22A0.770754303
NUDT15KIAA15860.762742303
NUDT15SEL1L30.756689303
NUDT15TMTC40.756384303
NUDT15THUMPD30.74947303
NUDT15MITD10.746008303
NUDT15EXOC80.745088404
NUDT15PGGT1B0.740723303
NUDT15NBN0.736533303
NUDT15NIPA10.728601303
NUDT15MPP60.724154303
NUDT15UBTD20.721244303
NUDT15HRH10.720859303
NUDT15BAIAP2L20.720151303
NUDT15RNF1490.715511303
NUDT15ZNF354A0.711589303
NUDT15MDM20.705467303

For details and further investigation, click here