| Full name: solute carrier family 19 member 1 | Alias Symbol: FOLT|RFC1 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 6573 | HGNC ID: HGNC:10937 | Ensembl Gene: ENSG00000173638 | OMIM ID: 600424 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC19A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | SLC19A1 | 6573 | 77100 | 1.1711 | 0.0000 | |
| GSE53624 | SLC19A1 | 6573 | 77100 | 1.0689 | 0.0000 | |
| GSE97050 | SLC19A1 | 6573 | A_33_P3265549 | 0.6917 | 0.1694 | |
| SRP007169 | SLC19A1 | 6573 | RNAseq | 2.2894 | 0.0001 | |
| SRP008496 | SLC19A1 | 6573 | RNAseq | 1.8859 | 0.0000 | |
| SRP064894 | SLC19A1 | 6573 | RNAseq | 2.2942 | 0.0000 | |
| SRP133303 | SLC19A1 | 6573 | RNAseq | 1.1403 | 0.0000 | |
| SRP159526 | SLC19A1 | 6573 | RNAseq | 2.0539 | 0.0000 | |
| SRP193095 | SLC19A1 | 6573 | RNAseq | 0.8446 | 0.0031 | |
| SRP219564 | SLC19A1 | 6573 | RNAseq | 2.2137 | 0.0002 | |
| TCGA | SLC19A1 | 6573 | RNAseq | 0.1406 | 0.1633 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by SLC19A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC19A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC19A1 | 6573 | 2 | 9 | 19 | |
| GSE20123 | SLC19A1 | 6573 | 2 | 8 | 20 | |
| GSE43470 | SLC19A1 | 6573 | 0 | 14 | 29 | |
| GSE46452 | SLC19A1 | 6573 | 1 | 21 | 37 | |
| GSE47630 | SLC19A1 | 6573 | 6 | 17 | 17 | |
| GSE54993 | SLC19A1 | 6573 | 8 | 1 | 61 | |
| GSE54994 | SLC19A1 | 6573 | 5 | 8 | 40 | |
| GSE60625 | SLC19A1 | 6573 | 0 | 0 | 11 | |
| GSE74703 | SLC19A1 | 6573 | 0 | 10 | 26 | |
| GSE74704 | SLC19A1 | 6573 | 1 | 4 | 15 | |
| TCGA | SLC19A1 | 6573 | 9 | 38 | 49 |
Total number of gains: 34; Total number of losses: 130; Total Number of normals: 324.
Somatic mutations of SLC19A1:
Generating mutation plots.
Highly correlated genes for SLC19A1:
Showing top 20/452 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC19A1 | MYBL2 | 0.827919 | 3 | 0 | 3 |
| SLC19A1 | DNMT1 | 0.795075 | 3 | 0 | 3 |
| SLC19A1 | SLC26A6 | 0.794778 | 3 | 0 | 3 |
| SLC19A1 | AURKA | 0.786072 | 3 | 0 | 3 |
| SLC19A1 | UBE2C | 0.784023 | 3 | 0 | 3 |
| SLC19A1 | TOP2A | 0.782368 | 3 | 0 | 3 |
| SLC19A1 | ATXN2L | 0.782247 | 3 | 0 | 3 |
| SLC19A1 | TTYH3 | 0.77162 | 3 | 0 | 3 |
| SLC19A1 | PLAU | 0.767979 | 3 | 0 | 3 |
| SLC19A1 | IGF2BP2 | 0.766977 | 3 | 0 | 3 |
| SLC19A1 | MMP1 | 0.760735 | 3 | 0 | 3 |
| SLC19A1 | MAZ | 0.760598 | 3 | 0 | 3 |
| SLC19A1 | NCLN | 0.759695 | 3 | 0 | 3 |
| SLC19A1 | MTHFD2 | 0.759665 | 3 | 0 | 3 |
| SLC19A1 | COL4A1 | 0.758106 | 3 | 0 | 3 |
| SLC19A1 | C4orf48 | 0.757842 | 3 | 0 | 3 |
| SLC19A1 | PLK1 | 0.755361 | 3 | 0 | 3 |
| SLC19A1 | LEPR | 0.754787 | 3 | 0 | 3 |
| SLC19A1 | TGFBI | 0.752697 | 3 | 0 | 3 |
| SLC19A1 | FANCB | 0.75236 | 3 | 0 | 3 |
For details and further investigation, click here
