| Full name: proline rich 14 | Alias Symbol: MGC3121 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 78994 | HGNC ID: HGNC:28458 | Ensembl Gene: ENSG00000156858 | OMIM ID: 617423 |
| Drug and gene relationship at DGIdb | |||
Expression of PRR14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR14 | 78994 | 45687_at | 0.2894 | 0.3857 | |
| GSE20347 | PRR14 | 78994 | 45687_at | 0.2652 | 0.0046 | |
| GSE23400 | PRR14 | 78994 | 45687_at | 0.1288 | 0.0001 | |
| GSE26886 | PRR14 | 78994 | 45687_at | 0.5304 | 0.0024 | |
| GSE29001 | PRR14 | 78994 | 45687_at | 0.0520 | 0.8002 | |
| GSE38129 | PRR14 | 78994 | 45687_at | 0.1193 | 0.1154 | |
| GSE45670 | PRR14 | 78994 | 45687_at | 0.2031 | 0.0546 | |
| GSE53622 | PRR14 | 78994 | 68031 | 0.1473 | 0.0073 | |
| GSE53624 | PRR14 | 78994 | 68031 | 0.2896 | 0.0000 | |
| GSE63941 | PRR14 | 78994 | 45687_at | 0.3098 | 0.3144 | |
| GSE77861 | PRR14 | 78994 | 45687_at | 0.1450 | 0.2444 | |
| GSE97050 | PRR14 | 78994 | A_23_P49412 | 0.1959 | 0.4700 | |
| SRP007169 | PRR14 | 78994 | RNAseq | -0.6605 | 0.1360 | |
| SRP008496 | PRR14 | 78994 | RNAseq | -0.7319 | 0.0150 | |
| SRP064894 | PRR14 | 78994 | RNAseq | 0.3370 | 0.1098 | |
| SRP133303 | PRR14 | 78994 | RNAseq | 0.1181 | 0.3517 | |
| SRP159526 | PRR14 | 78994 | RNAseq | 0.0867 | 0.7789 | |
| SRP193095 | PRR14 | 78994 | RNAseq | 0.1192 | 0.2971 | |
| SRP219564 | PRR14 | 78994 | RNAseq | -0.0195 | 0.9296 | |
| TCGA | PRR14 | 78994 | RNAseq | 0.0280 | 0.5754 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRR14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR14 | 78994 | 5 | 5 | 20 | |
| GSE20123 | PRR14 | 78994 | 5 | 4 | 21 | |
| GSE43470 | PRR14 | 78994 | 3 | 3 | 37 | |
| GSE46452 | PRR14 | 78994 | 38 | 1 | 20 | |
| GSE47630 | PRR14 | 78994 | 11 | 7 | 22 | |
| GSE54993 | PRR14 | 78994 | 2 | 5 | 63 | |
| GSE54994 | PRR14 | 78994 | 5 | 9 | 39 | |
| GSE60625 | PRR14 | 78994 | 4 | 0 | 7 | |
| GSE74703 | PRR14 | 78994 | 3 | 2 | 31 | |
| GSE74704 | PRR14 | 78994 | 3 | 2 | 15 | |
| TCGA | PRR14 | 78994 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of PRR14:
Generating mutation plots.
Highly correlated genes for PRR14:
Showing top 20/654 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR14 | USP34 | 0.826644 | 3 | 0 | 3 |
| PRR14 | RPS19BP1 | 0.798565 | 3 | 0 | 3 |
| PRR14 | TDP2 | 0.780264 | 3 | 0 | 3 |
| PRR14 | ABCF1 | 0.77125 | 4 | 0 | 4 |
| PRR14 | BUD31 | 0.761382 | 3 | 0 | 3 |
| PRR14 | KEAP1 | 0.742525 | 4 | 0 | 4 |
| PRR14 | KRTCAP2 | 0.737177 | 3 | 0 | 3 |
| PRR14 | MRPL41 | 0.731512 | 3 | 0 | 3 |
| PRR14 | MRPS26 | 0.730393 | 4 | 0 | 4 |
| PRR14 | RPL7L1 | 0.730119 | 3 | 0 | 3 |
| PRR14 | FABP4 | 0.722258 | 3 | 0 | 3 |
| PRR14 | CRTC2 | 0.721317 | 4 | 0 | 4 |
| PRR14 | KIAA0040 | 0.720965 | 3 | 0 | 3 |
| PRR14 | TBC1D25 | 0.720738 | 4 | 0 | 4 |
| PRR14 | LNP1 | 0.719662 | 3 | 0 | 3 |
| PRR14 | PYGO1 | 0.715146 | 3 | 0 | 3 |
| PRR14 | DMAP1 | 0.714376 | 3 | 0 | 3 |
| PRR14 | KLF13 | 0.713405 | 3 | 0 | 3 |
| PRR14 | B9D2 | 0.711531 | 3 | 0 | 3 |
| PRR14 | LRRC34 | 0.711047 | 3 | 0 | 3 |
For details and further investigation, click here
