| Full name: fatty acid binding protein 4 | Alias Symbol: A-FABP|aP2 | ||
| Type: protein-coding gene | Cytoband: 8q21.13 | ||
| Entrez ID: 2167 | HGNC ID: HGNC:3559 | Ensembl Gene: ENSG00000170323 | OMIM ID: 600434 |
| Drug and gene relationship at DGIdb | |||
FABP4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of FABP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FABP4 | 2167 | 203980_at | 0.2178 | 0.9307 | |
| GSE20347 | FABP4 | 2167 | 203980_at | 0.8523 | 0.3438 | |
| GSE23400 | FABP4 | 2167 | 203980_at | -0.2106 | 0.5818 | |
| GSE26886 | FABP4 | 2167 | 203980_at | 1.9889 | 0.0218 | |
| GSE29001 | FABP4 | 2167 | 203980_at | 0.5602 | 0.4851 | |
| GSE38129 | FABP4 | 2167 | 203980_at | 0.0819 | 0.9320 | |
| GSE45670 | FABP4 | 2167 | 203980_at | -0.3290 | 0.8076 | |
| GSE53622 | FABP4 | 2167 | 3657 | -0.6939 | 0.1088 | |
| GSE53624 | FABP4 | 2167 | 3657 | -0.3392 | 0.3587 | |
| GSE63941 | FABP4 | 2167 | 203980_at | -0.6088 | 0.7587 | |
| GSE77861 | FABP4 | 2167 | 203980_at | 2.2873 | 0.0410 | |
| GSE97050 | FABP4 | 2167 | A_23_P8820 | 1.8922 | 0.2289 | |
| SRP064894 | FABP4 | 2167 | RNAseq | 1.7985 | 0.0089 | |
| SRP133303 | FABP4 | 2167 | RNAseq | 1.0358 | 0.2272 | |
| SRP159526 | FABP4 | 2167 | RNAseq | 1.4781 | 0.1782 | |
| SRP193095 | FABP4 | 2167 | RNAseq | 5.4496 | 0.0000 | |
| SRP219564 | FABP4 | 2167 | RNAseq | -0.8755 | 0.3444 | |
| TCGA | FABP4 | 2167 | RNAseq | -0.1380 | 0.7578 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FABP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FABP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FABP4 | 2167 | 16 | 1 | 13 | |
| GSE20123 | FABP4 | 2167 | 18 | 1 | 11 | |
| GSE43470 | FABP4 | 2167 | 18 | 1 | 24 | |
| GSE46452 | FABP4 | 2167 | 21 | 0 | 38 | |
| GSE47630 | FABP4 | 2167 | 23 | 0 | 17 | |
| GSE54993 | FABP4 | 2167 | 0 | 19 | 51 | |
| GSE54994 | FABP4 | 2167 | 30 | 0 | 23 | |
| GSE60625 | FABP4 | 2167 | 0 | 4 | 7 | |
| GSE74703 | FABP4 | 2167 | 15 | 1 | 20 | |
| GSE74704 | FABP4 | 2167 | 12 | 0 | 8 | |
| TCGA | FABP4 | 2167 | 50 | 3 | 43 |
Total number of gains: 203; Total number of losses: 30; Total Number of normals: 255.
Somatic mutations of FABP4:
Generating mutation plots.
Highly correlated genes for FABP4:
Showing top 20/238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FABP4 | PTGFRN | 0.731985 | 3 | 0 | 3 |
| FABP4 | STK17A | 0.728121 | 3 | 0 | 3 |
| FABP4 | PRR14 | 0.722258 | 3 | 0 | 3 |
| FABP4 | KIAA0930 | 0.719472 | 4 | 0 | 4 |
| FABP4 | F2RL1 | 0.716426 | 3 | 0 | 3 |
| FABP4 | CCNE1 | 0.714741 | 3 | 0 | 3 |
| FABP4 | CASK | 0.713482 | 3 | 0 | 3 |
| FABP4 | CCNA1 | 0.70845 | 3 | 0 | 3 |
| FABP4 | TACO1 | 0.707129 | 3 | 0 | 3 |
| FABP4 | GMPS | 0.706301 | 3 | 0 | 3 |
| FABP4 | MTMR11 | 0.705357 | 3 | 0 | 3 |
| FABP4 | SETD1A | 0.703367 | 3 | 0 | 3 |
| FABP4 | MAGEF1 | 0.701019 | 3 | 0 | 3 |
| FABP4 | NUP43 | 0.698692 | 3 | 0 | 3 |
| FABP4 | TWISTNB | 0.698461 | 4 | 0 | 4 |
| FABP4 | CLSTN2 | 0.698073 | 3 | 0 | 3 |
| FABP4 | MMP3 | 0.697836 | 4 | 0 | 4 |
| FABP4 | TM2D3 | 0.693728 | 3 | 0 | 3 |
| FABP4 | C20orf27 | 0.692804 | 3 | 0 | 3 |
| FABP4 | RNASEH1 | 0.691734 | 3 | 0 | 3 |
For details and further investigation, click here
