| Full name: ubiquitin specific peptidase 34 | Alias Symbol: KIAA0570|KIAA0729 | ||
| Type: protein-coding gene | Cytoband: 2p15 | ||
| Entrez ID: 9736 | HGNC ID: HGNC:20066 | Ensembl Gene: ENSG00000115464 | OMIM ID: 615295 |
| Drug and gene relationship at DGIdb | |||
Expression of USP34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP34 | 9736 | 212066_s_at | 0.2717 | 0.5204 | |
| GSE20347 | USP34 | 9736 | 207365_x_at | 0.5230 | 0.0312 | |
| GSE23400 | USP34 | 9736 | 207365_x_at | 0.1540 | 0.0171 | |
| GSE26886 | USP34 | 9736 | 212066_s_at | 0.3019 | 0.1143 | |
| GSE29001 | USP34 | 9736 | 212066_s_at | 0.1806 | 0.2695 | |
| GSE38129 | USP34 | 9736 | 207365_x_at | 0.2710 | 0.3479 | |
| GSE45670 | USP34 | 9736 | 212066_s_at | -0.0127 | 0.9281 | |
| GSE63941 | USP34 | 9736 | 212066_s_at | -0.4254 | 0.2931 | |
| GSE77861 | USP34 | 9736 | 207365_x_at | 0.7689 | 0.0631 | |
| GSE97050 | USP34 | 9736 | A_24_P126417 | 0.0633 | 0.8347 | |
| SRP007169 | USP34 | 9736 | RNAseq | 0.7169 | 0.0458 | |
| SRP008496 | USP34 | 9736 | RNAseq | 0.7094 | 0.0001 | |
| SRP064894 | USP34 | 9736 | RNAseq | -0.0524 | 0.7942 | |
| SRP133303 | USP34 | 9736 | RNAseq | 0.1762 | 0.1266 | |
| SRP159526 | USP34 | 9736 | RNAseq | 0.2802 | 0.2631 | |
| SRP193095 | USP34 | 9736 | RNAseq | 0.1536 | 0.0797 | |
| SRP219564 | USP34 | 9736 | RNAseq | -0.2306 | 0.2675 | |
| TCGA | USP34 | 9736 | RNAseq | -0.0844 | 0.0358 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP34 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of USP34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP34 | 9736 | 12 | 0 | 18 | |
| GSE20123 | USP34 | 9736 | 11 | 0 | 19 | |
| GSE43470 | USP34 | 9736 | 7 | 0 | 36 | |
| GSE46452 | USP34 | 9736 | 2 | 3 | 54 | |
| GSE47630 | USP34 | 9736 | 8 | 0 | 32 | |
| GSE54993 | USP34 | 9736 | 0 | 6 | 64 | |
| GSE54994 | USP34 | 9736 | 12 | 0 | 41 | |
| GSE60625 | USP34 | 9736 | 0 | 3 | 8 | |
| GSE74703 | USP34 | 9736 | 7 | 0 | 29 | |
| GSE74704 | USP34 | 9736 | 10 | 0 | 10 | |
| TCGA | USP34 | 9736 | 36 | 4 | 56 |
Total number of gains: 105; Total number of losses: 16; Total Number of normals: 367.
Somatic mutations of USP34:
Generating mutation plots.
Highly correlated genes for USP34:
Showing top 20/497 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP34 | MAGI1 | 0.836922 | 4 | 0 | 4 |
| USP34 | DDX20 | 0.831437 | 3 | 0 | 3 |
| USP34 | PRR14 | 0.826644 | 3 | 0 | 3 |
| USP34 | POLR1B | 0.821652 | 6 | 0 | 6 |
| USP34 | BRCA1 | 0.813585 | 3 | 0 | 3 |
| USP34 | SH2B2 | 0.808339 | 5 | 0 | 5 |
| USP34 | ATP8B1 | 0.808081 | 6 | 0 | 5 |
| USP34 | ZNF317 | 0.806485 | 3 | 0 | 3 |
| USP34 | RHBDD2 | 0.805659 | 3 | 0 | 3 |
| USP34 | TMEM205 | 0.803207 | 3 | 0 | 3 |
| USP34 | KLHL24 | 0.791641 | 7 | 0 | 6 |
| USP34 | ALMS1 | 0.791196 | 7 | 0 | 6 |
| USP34 | RUNDC1 | 0.791075 | 3 | 0 | 3 |
| USP34 | ANKIB1 | 0.78798 | 3 | 0 | 3 |
| USP34 | C1orf122 | 0.778714 | 3 | 0 | 3 |
| USP34 | LRRC34 | 0.772943 | 3 | 0 | 3 |
| USP34 | POMGNT1 | 0.765779 | 3 | 0 | 3 |
| USP34 | CTPS2 | 0.748932 | 3 | 0 | 3 |
| USP34 | OTUD7B | 0.747167 | 3 | 0 | 3 |
| USP34 | FBXO33 | 0.746232 | 3 | 0 | 3 |
For details and further investigation, click here
