| Full name: paired related homeobox 2 | Alias Symbol: PRX2|PMX2 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 51450 | HGNC ID: HGNC:21338 | Ensembl Gene: ENSG00000167157 | OMIM ID: 604675 |
| Drug and gene relationship at DGIdb | |||
Expression of PRRX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRRX2 | 51450 | 219729_at | 0.5974 | 0.0423 | |
| GSE20347 | PRRX2 | 51450 | 219729_at | 0.4464 | 0.0057 | |
| GSE23400 | PRRX2 | 51450 | 219729_at | 0.0933 | 0.0172 | |
| GSE26886 | PRRX2 | 51450 | 219729_at | 0.8606 | 0.0000 | |
| GSE29001 | PRRX2 | 51450 | 219729_at | 0.0362 | 0.8579 | |
| GSE38129 | PRRX2 | 51450 | 219729_at | 0.3413 | 0.0163 | |
| GSE45670 | PRRX2 | 51450 | 219729_at | 0.1960 | 0.1532 | |
| GSE53622 | PRRX2 | 51450 | 123381 | 0.9612 | 0.0000 | |
| GSE53624 | PRRX2 | 51450 | 123381 | 1.7282 | 0.0000 | |
| GSE63941 | PRRX2 | 51450 | 219729_at | -1.5509 | 0.0010 | |
| GSE77861 | PRRX2 | 51450 | 219729_at | 0.5979 | 0.0052 | |
| GSE97050 | PRRX2 | 51450 | A_23_P83298 | 0.5193 | 0.3408 | |
| SRP064894 | PRRX2 | 51450 | RNAseq | 1.5856 | 0.0011 | |
| SRP133303 | PRRX2 | 51450 | RNAseq | 1.7946 | 0.0000 | |
| SRP159526 | PRRX2 | 51450 | RNAseq | 1.7779 | 0.0007 | |
| SRP219564 | PRRX2 | 51450 | RNAseq | 2.5851 | 0.0000 | |
| TCGA | PRRX2 | 51450 | RNAseq | 1.0854 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by PRRX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRRX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRRX2 | 51450 | 6 | 9 | 15 | |
| GSE20123 | PRRX2 | 51450 | 6 | 9 | 15 | |
| GSE43470 | PRRX2 | 51450 | 5 | 8 | 30 | |
| GSE46452 | PRRX2 | 51450 | 6 | 13 | 40 | |
| GSE47630 | PRRX2 | 51450 | 3 | 16 | 21 | |
| GSE54993 | PRRX2 | 51450 | 3 | 3 | 64 | |
| GSE54994 | PRRX2 | 51450 | 12 | 9 | 32 | |
| GSE60625 | PRRX2 | 51450 | 0 | 0 | 11 | |
| GSE74703 | PRRX2 | 51450 | 5 | 6 | 25 | |
| GSE74704 | PRRX2 | 51450 | 3 | 7 | 10 | |
| TCGA | PRRX2 | 51450 | 27 | 26 | 43 |
Total number of gains: 76; Total number of losses: 106; Total Number of normals: 306.
Somatic mutations of PRRX2:
Generating mutation plots.
Highly correlated genes for PRRX2:
Showing top 20/1046 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRRX2 | MRC2 | 0.74718 | 3 | 0 | 3 |
| PRRX2 | ADO | 0.741407 | 3 | 0 | 3 |
| PRRX2 | KRTCAP2 | 0.741005 | 4 | 0 | 4 |
| PRRX2 | VASP | 0.739944 | 3 | 0 | 3 |
| PRRX2 | COX7A2L | 0.727539 | 3 | 0 | 3 |
| PRRX2 | ZNF496 | 0.721173 | 4 | 0 | 4 |
| PRRX2 | ZNF358 | 0.719607 | 3 | 0 | 3 |
| PRRX2 | NUP43 | 0.717207 | 3 | 0 | 3 |
| PRRX2 | HES6 | 0.716736 | 4 | 0 | 4 |
| PRRX2 | WDR81 | 0.706509 | 3 | 0 | 3 |
| PRRX2 | UBE2D4 | 0.70457 | 4 | 0 | 4 |
| PRRX2 | C12orf57 | 0.70361 | 3 | 0 | 3 |
| PRRX2 | PCBP3 | 0.70185 | 3 | 0 | 3 |
| PRRX2 | LTBP2 | 0.694374 | 3 | 0 | 3 |
| PRRX2 | TSHR | 0.693522 | 3 | 0 | 3 |
| PRRX2 | RNMT | 0.688194 | 3 | 0 | 3 |
| PRRX2 | NGF | 0.688172 | 4 | 0 | 4 |
| PRRX2 | CRLF1 | 0.682073 | 4 | 0 | 3 |
| PRRX2 | TP53I13 | 0.681442 | 6 | 0 | 4 |
| PRRX2 | HABP4 | 0.680797 | 4 | 0 | 4 |
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