| Full name: cytokine receptor like factor 1 | Alias Symbol: CLF-1|CLF|CISS|CISS1 | ||
| Type: protein-coding gene | Cytoband: 19p12 | ||
| Entrez ID: 9244 | HGNC ID: HGNC:2364 | Ensembl Gene: ENSG00000006016 | OMIM ID: 604237 |
| Drug and gene relationship at DGIdb | |||
Expression of CRLF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRLF1 | 9244 | 206315_at | -0.1909 | 0.6677 | |
| GSE20347 | CRLF1 | 9244 | 206315_at | 0.4390 | 0.0573 | |
| GSE23400 | CRLF1 | 9244 | 206315_at | -0.0627 | 0.4779 | |
| GSE26886 | CRLF1 | 9244 | 206315_at | 1.1103 | 0.0004 | |
| GSE29001 | CRLF1 | 9244 | 206315_at | 0.7076 | 0.0955 | |
| GSE38129 | CRLF1 | 9244 | 206315_at | 0.1180 | 0.6076 | |
| GSE45670 | CRLF1 | 9244 | 206315_at | -0.5816 | 0.0216 | |
| GSE53622 | CRLF1 | 9244 | 32178 | -1.4665 | 0.0000 | |
| GSE53624 | CRLF1 | 9244 | 32178 | -0.2578 | 0.2403 | |
| GSE63941 | CRLF1 | 9244 | 206315_at | -3.9158 | 0.0004 | |
| GSE77861 | CRLF1 | 9244 | 206315_at | 0.0007 | 0.9957 | |
| GSE97050 | CRLF1 | 9244 | A_33_P3252286 | 0.1608 | 0.7707 | |
| SRP064894 | CRLF1 | 9244 | RNAseq | -1.6065 | 0.0003 | |
| SRP133303 | CRLF1 | 9244 | RNAseq | -0.7762 | 0.0138 | |
| SRP159526 | CRLF1 | 9244 | RNAseq | 0.7228 | 0.4285 | |
| SRP219564 | CRLF1 | 9244 | RNAseq | 1.4875 | 0.1089 | |
| TCGA | CRLF1 | 9244 | RNAseq | 0.1301 | 0.6060 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by CRLF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRLF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRLF1 | 9244 | 4 | 5 | 21 | |
| GSE20123 | CRLF1 | 9244 | 3 | 3 | 24 | |
| GSE43470 | CRLF1 | 9244 | 2 | 5 | 36 | |
| GSE46452 | CRLF1 | 9244 | 47 | 1 | 11 | |
| GSE47630 | CRLF1 | 9244 | 4 | 8 | 28 | |
| GSE54993 | CRLF1 | 9244 | 15 | 4 | 51 | |
| GSE54994 | CRLF1 | 9244 | 6 | 13 | 34 | |
| GSE60625 | CRLF1 | 9244 | 9 | 0 | 2 | |
| GSE74703 | CRLF1 | 9244 | 2 | 3 | 31 | |
| GSE74704 | CRLF1 | 9244 | 0 | 3 | 17 | |
| TCGA | CRLF1 | 9244 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of CRLF1:
Generating mutation plots.
Highly correlated genes for CRLF1:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRLF1 | ST3GAL2 | 0.7941 | 3 | 0 | 3 |
| CRLF1 | FAM167B | 0.771816 | 3 | 0 | 3 |
| CRLF1 | SH3PXD2B | 0.740605 | 3 | 0 | 3 |
| CRLF1 | CPT1C | 0.733269 | 3 | 0 | 3 |
| CRLF1 | C11orf96 | 0.7205 | 4 | 0 | 3 |
| CRLF1 | APBB1 | 0.719865 | 3 | 0 | 3 |
| CRLF1 | CCL7 | 0.715276 | 3 | 0 | 3 |
| CRLF1 | FHL3 | 0.713976 | 3 | 0 | 3 |
| CRLF1 | MIER2 | 0.713044 | 3 | 0 | 3 |
| CRLF1 | HSD11B1 | 0.707839 | 3 | 0 | 3 |
| CRLF1 | CCND3 | 0.707145 | 3 | 0 | 3 |
| CRLF1 | ZDHHC1 | 0.704735 | 3 | 0 | 3 |
| CRLF1 | SLC39A3 | 0.703757 | 3 | 0 | 3 |
| CRLF1 | TADA3 | 0.702591 | 3 | 0 | 3 |
| CRLF1 | TMTC1 | 0.694764 | 3 | 0 | 3 |
| CRLF1 | TSHZ3 | 0.693627 | 4 | 0 | 3 |
| CRLF1 | B3GALT6 | 0.688585 | 3 | 0 | 3 |
| CRLF1 | TMEM214 | 0.683052 | 3 | 0 | 3 |
| CRLF1 | PRRX2 | 0.682073 | 4 | 0 | 3 |
| CRLF1 | DYRK3 | 0.681913 | 3 | 0 | 3 |
For details and further investigation, click here
