| Full name: RNA guanine-7 methyltransferase | Alias Symbol: RG7MT1 | ||
| Type: protein-coding gene | Cytoband: 18p11.21 | ||
| Entrez ID: 8731 | HGNC ID: HGNC:10075 | Ensembl Gene: ENSG00000101654 | OMIM ID: 603514 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RNMT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNMT | 8731 | 202683_s_at | 0.5382 | 0.2365 | |
| GSE20347 | RNMT | 8731 | 202683_s_at | 0.5192 | 0.0005 | |
| GSE23400 | RNMT | 8731 | 202683_s_at | 0.3352 | 0.0000 | |
| GSE26886 | RNMT | 8731 | 202683_s_at | 0.4804 | 0.0038 | |
| GSE29001 | RNMT | 8731 | 202683_s_at | 0.4917 | 0.0197 | |
| GSE38129 | RNMT | 8731 | 202683_s_at | 0.4455 | 0.0004 | |
| GSE45670 | RNMT | 8731 | 202683_s_at | 0.0445 | 0.7896 | |
| GSE53622 | RNMT | 8731 | 83355 | 0.0115 | 0.8898 | |
| GSE53624 | RNMT | 8731 | 42988 | 0.3107 | 0.0000 | |
| GSE63941 | RNMT | 8731 | 202683_s_at | 0.1053 | 0.8565 | |
| GSE77861 | RNMT | 8731 | 202683_s_at | 0.7265 | 0.0052 | |
| GSE97050 | RNMT | 8731 | A_23_P55515 | 0.2243 | 0.4104 | |
| SRP007169 | RNMT | 8731 | RNAseq | 0.7877 | 0.0551 | |
| SRP008496 | RNMT | 8731 | RNAseq | 0.6682 | 0.0348 | |
| SRP064894 | RNMT | 8731 | RNAseq | 0.1201 | 0.6567 | |
| SRP133303 | RNMT | 8731 | RNAseq | 0.3615 | 0.0198 | |
| SRP159526 | RNMT | 8731 | RNAseq | 0.1872 | 0.3977 | |
| SRP193095 | RNMT | 8731 | RNAseq | 0.1987 | 0.0734 | |
| SRP219564 | RNMT | 8731 | RNAseq | -0.1605 | 0.5216 | |
| TCGA | RNMT | 8731 | RNAseq | 0.0118 | 0.8077 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNMT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNMT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNMT | 8731 | 5 | 3 | 22 | |
| GSE20123 | RNMT | 8731 | 5 | 3 | 22 | |
| GSE43470 | RNMT | 8731 | 0 | 6 | 37 | |
| GSE46452 | RNMT | 8731 | 3 | 21 | 35 | |
| GSE47630 | RNMT | 8731 | 7 | 17 | 16 | |
| GSE54993 | RNMT | 8731 | 6 | 2 | 62 | |
| GSE54994 | RNMT | 8731 | 8 | 8 | 37 | |
| GSE60625 | RNMT | 8731 | 0 | 4 | 7 | |
| GSE74703 | RNMT | 8731 | 0 | 4 | 32 | |
| GSE74704 | RNMT | 8731 | 3 | 2 | 15 | |
| TCGA | RNMT | 8731 | 27 | 23 | 46 |
Total number of gains: 64; Total number of losses: 93; Total Number of normals: 331.
Somatic mutations of RNMT:
Generating mutation plots.
Highly correlated genes for RNMT:
Showing top 20/1279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNMT | G2E3 | 0.817533 | 3 | 0 | 3 |
| RNMT | BRMS1L | 0.797963 | 3 | 0 | 3 |
| RNMT | USP37 | 0.789919 | 3 | 0 | 3 |
| RNMT | WDR5 | 0.786895 | 3 | 0 | 3 |
| RNMT | UCP2 | 0.781706 | 3 | 0 | 3 |
| RNMT | TMEM138 | 0.77487 | 3 | 0 | 3 |
| RNMT | CRTC2 | 0.771334 | 3 | 0 | 3 |
| RNMT | UBTD2 | 0.760078 | 4 | 0 | 4 |
| RNMT | TUBA1B | 0.75896 | 5 | 0 | 5 |
| RNMT | ARL13B | 0.758806 | 4 | 0 | 3 |
| RNMT | TRIM59 | 0.756572 | 3 | 0 | 3 |
| RNMT | CAV2 | 0.75133 | 3 | 0 | 3 |
| RNMT | PTGFRN | 0.751023 | 3 | 0 | 3 |
| RNMT | AMMECR1L | 0.750717 | 4 | 0 | 3 |
| RNMT | TNRC18 | 0.74918 | 3 | 0 | 3 |
| RNMT | C1orf226 | 0.747735 | 3 | 0 | 3 |
| RNMT | ZNF623 | 0.746123 | 3 | 0 | 3 |
| RNMT | CPNE8 | 0.74506 | 3 | 0 | 3 |
| RNMT | KBTBD6 | 0.73831 | 3 | 0 | 3 |
| RNMT | STX16 | 0.730753 | 3 | 0 | 3 |
For details and further investigation, click here
