| Full name: ubiquitin conjugating enzyme E2 H | Alias Symbol: UBCH|UBC8|GID3 | ||
| Type: protein-coding gene | Cytoband: 7q32.2 | ||
| Entrez ID: 7328 | HGNC ID: HGNC:12484 | Ensembl Gene: ENSG00000186591 | OMIM ID: 601082 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2H | 7328 | 222421_at | -0.0172 | 0.9812 | |
| GSE20347 | UBE2H | 7328 | 217799_x_at | -0.0728 | 0.5584 | |
| GSE23400 | UBE2H | 7328 | 217799_x_at | -0.3356 | 0.0000 | |
| GSE26886 | UBE2H | 7328 | 222420_s_at | -1.2793 | 0.0004 | |
| GSE29001 | UBE2H | 7328 | 221962_s_at | -0.8132 | 0.0171 | |
| GSE38129 | UBE2H | 7328 | 217799_x_at | 0.0158 | 0.9146 | |
| GSE45670 | UBE2H | 7328 | 222420_s_at | 0.2114 | 0.2133 | |
| GSE53622 | UBE2H | 7328 | 49086 | -0.0370 | 0.6022 | |
| GSE53624 | UBE2H | 7328 | 49086 | -0.0556 | 0.2967 | |
| GSE63941 | UBE2H | 7328 | 222420_s_at | -0.9667 | 0.1247 | |
| GSE77861 | UBE2H | 7328 | 222421_at | 0.5503 | 0.0572 | |
| GSE97050 | UBE2H | 7328 | A_33_P3341234 | 0.0125 | 0.9732 | |
| SRP007169 | UBE2H | 7328 | RNAseq | 0.4117 | 0.3065 | |
| SRP008496 | UBE2H | 7328 | RNAseq | 0.4475 | 0.0312 | |
| SRP064894 | UBE2H | 7328 | RNAseq | -0.2861 | 0.0641 | |
| SRP133303 | UBE2H | 7328 | RNAseq | 0.2780 | 0.1266 | |
| SRP159526 | UBE2H | 7328 | RNAseq | -0.0331 | 0.9240 | |
| SRP193095 | UBE2H | 7328 | RNAseq | -0.1255 | 0.4050 | |
| SRP219564 | UBE2H | 7328 | RNAseq | -0.6540 | 0.0196 | |
| TCGA | UBE2H | 7328 | RNAseq | 0.0240 | 0.6415 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UBE2H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2H | 7328 | 8 | 1 | 21 | |
| GSE20123 | UBE2H | 7328 | 8 | 1 | 21 | |
| GSE43470 | UBE2H | 7328 | 2 | 3 | 38 | |
| GSE46452 | UBE2H | 7328 | 7 | 2 | 50 | |
| GSE47630 | UBE2H | 7328 | 7 | 4 | 29 | |
| GSE54993 | UBE2H | 7328 | 3 | 5 | 62 | |
| GSE54994 | UBE2H | 7328 | 7 | 8 | 38 | |
| GSE60625 | UBE2H | 7328 | 0 | 0 | 11 | |
| GSE74703 | UBE2H | 7328 | 2 | 3 | 31 | |
| GSE74704 | UBE2H | 7328 | 4 | 1 | 15 | |
| TCGA | UBE2H | 7328 | 29 | 21 | 46 |
Total number of gains: 77; Total number of losses: 49; Total Number of normals: 362.
Somatic mutations of UBE2H:
Generating mutation plots.
Highly correlated genes for UBE2H:
Showing top 20/166 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2H | RSBN1 | 0.756421 | 3 | 0 | 3 |
| UBE2H | STK40 | 0.756194 | 3 | 0 | 3 |
| UBE2H | PUS7L | 0.748978 | 3 | 0 | 3 |
| UBE2H | N4BP1 | 0.71084 | 3 | 0 | 3 |
| UBE2H | TRAPPC2 | 0.701145 | 3 | 0 | 3 |
| UBE2H | C2CD2 | 0.692108 | 3 | 0 | 3 |
| UBE2H | TMEM17 | 0.686221 | 3 | 0 | 3 |
| UBE2H | TERF2IP | 0.685745 | 3 | 0 | 3 |
| UBE2H | RHBDD1 | 0.680278 | 4 | 0 | 4 |
| UBE2H | ZNF506 | 0.675067 | 3 | 0 | 3 |
| UBE2H | CDK5RAP3 | 0.670087 | 3 | 0 | 3 |
| UBE2H | IFT46 | 0.66894 | 3 | 0 | 3 |
| UBE2H | NDUFS3 | 0.665949 | 3 | 0 | 3 |
| UBE2H | TMEM219 | 0.664002 | 3 | 0 | 3 |
| UBE2H | DYNC1LI2 | 0.66252 | 3 | 0 | 3 |
| UBE2H | PJA2 | 0.661529 | 3 | 0 | 3 |
| UBE2H | C6orf89 | 0.655417 | 3 | 0 | 3 |
| UBE2H | C17orf80 | 0.654888 | 3 | 0 | 3 |
| UBE2H | TFCP2 | 0.652905 | 3 | 0 | 3 |
| UBE2H | WWP1 | 0.648887 | 3 | 0 | 3 |
For details and further investigation, click here
