| Full name: ELOVL fatty acid elongase 1 | Alias Symbol: Ssc1 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 64834 | HGNC ID: HGNC:14418 | Ensembl Gene: ENSG00000066322 | OMIM ID: 611813 |
| Drug and gene relationship at DGIdb | |||
Expression of ELOVL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ELOVL1 | 64834 | 126265 | -0.6013 | 0.0000 | |
| GSE53624 | ELOVL1 | 64834 | 126265 | -0.8188 | 0.0000 | |
| GSE97050 | ELOVL1 | 64834 | A_23_P23380 | 0.3787 | 0.4183 | |
| SRP007169 | ELOVL1 | 64834 | RNAseq | -2.0694 | 0.0000 | |
| SRP008496 | ELOVL1 | 64834 | RNAseq | -2.0169 | 0.0000 | |
| SRP064894 | ELOVL1 | 64834 | RNAseq | -0.7273 | 0.0000 | |
| SRP133303 | ELOVL1 | 64834 | RNAseq | -0.5925 | 0.0003 | |
| SRP159526 | ELOVL1 | 64834 | RNAseq | -0.8322 | 0.0699 | |
| SRP193095 | ELOVL1 | 64834 | RNAseq | -1.1154 | 0.0000 | |
| SRP219564 | ELOVL1 | 64834 | RNAseq | -0.6063 | 0.2399 | |
| TCGA | ELOVL1 | 64834 | RNAseq | 0.0180 | 0.7760 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ELOVL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELOVL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELOVL1 | 64834 | 4 | 3 | 23 | |
| GSE20123 | ELOVL1 | 64834 | 4 | 2 | 24 | |
| GSE43470 | ELOVL1 | 64834 | 7 | 2 | 34 | |
| GSE46452 | ELOVL1 | 64834 | 3 | 1 | 55 | |
| GSE47630 | ELOVL1 | 64834 | 9 | 2 | 29 | |
| GSE54993 | ELOVL1 | 64834 | 0 | 2 | 68 | |
| GSE54994 | ELOVL1 | 64834 | 13 | 2 | 38 | |
| GSE60625 | ELOVL1 | 64834 | 0 | 0 | 11 | |
| GSE74703 | ELOVL1 | 64834 | 6 | 1 | 29 | |
| GSE74704 | ELOVL1 | 64834 | 2 | 0 | 18 | |
| TCGA | ELOVL1 | 64834 | 13 | 16 | 67 |
Total number of gains: 61; Total number of losses: 31; Total Number of normals: 396.
Somatic mutations of ELOVL1:
Generating mutation plots.
Highly correlated genes for ELOVL1:
Showing top 20/482 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELOVL1 | PLIN3 | 0.811639 | 3 | 0 | 3 |
| ELOVL1 | PPP1R13L | 0.800776 | 3 | 0 | 3 |
| ELOVL1 | MIOS | 0.793337 | 3 | 0 | 3 |
| ELOVL1 | DAPP1 | 0.793262 | 3 | 0 | 3 |
| ELOVL1 | CDA | 0.791854 | 3 | 0 | 3 |
| ELOVL1 | SH3GL1 | 0.78446 | 3 | 0 | 3 |
| ELOVL1 | TOM1 | 0.769236 | 3 | 0 | 3 |
| ELOVL1 | FBXL16 | 0.764153 | 3 | 0 | 3 |
| ELOVL1 | MBD2 | 0.759 | 3 | 0 | 3 |
| ELOVL1 | TSG101 | 0.758115 | 3 | 0 | 3 |
| ELOVL1 | STXBP5 | 0.753882 | 3 | 0 | 3 |
| ELOVL1 | CST6 | 0.753805 | 3 | 0 | 3 |
| ELOVL1 | MTPN | 0.753521 | 3 | 0 | 3 |
| ELOVL1 | NAGK | 0.75164 | 3 | 0 | 3 |
| ELOVL1 | CD82 | 0.750614 | 3 | 0 | 3 |
| ELOVL1 | PLD2 | 0.749427 | 3 | 0 | 3 |
| ELOVL1 | MFSD5 | 0.748075 | 4 | 0 | 4 |
| ELOVL1 | CSK | 0.748049 | 3 | 0 | 3 |
| ELOVL1 | EZR | 0.747914 | 3 | 0 | 3 |
| ELOVL1 | TWF1 | 0.746819 | 3 | 0 | 3 |
For details and further investigation, click here
