| Full name: X-linked inhibitor of apoptosis | Alias Symbol: hILP|ILP-1 | ||
| Type: protein-coding gene | Cytoband: Xq25 | ||
| Entrez ID: 331 | HGNC ID: HGNC:592 | Ensembl Gene: ENSG00000101966 | OMIM ID: 300079 |
| Drug and gene relationship at DGIdb | |||
XIAP involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04064 | NF-kappa B signaling pathway | |
| hsa04210 | Apoptosis | |
| hsa04510 | Focal adhesion | |
| hsa05145 | Toxoplasmosis | |
| hsa05200 | Pathways in cancer | |
| hsa05222 | Small cell lung cancer |
Expression of XIAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XIAP | 331 | 228363_at | 0.0537 | 0.8971 | |
| GSE20347 | XIAP | 331 | 206536_s_at | -0.3223 | 0.0050 | |
| GSE23400 | XIAP | 331 | 206536_s_at | -0.0882 | 0.0136 | |
| GSE26886 | XIAP | 331 | 228363_at | 0.3487 | 0.0763 | |
| GSE29001 | XIAP | 331 | 206537_at | -0.2611 | 0.0586 | |
| GSE38129 | XIAP | 331 | 206536_s_at | -0.1462 | 0.3452 | |
| GSE45670 | XIAP | 331 | 228363_at | 0.2086 | 0.1689 | |
| GSE53622 | XIAP | 331 | 85997 | 0.3773 | 0.0002 | |
| GSE53624 | XIAP | 331 | 85997 | 0.1624 | 0.0100 | |
| GSE63941 | XIAP | 331 | 228363_at | 0.0056 | 0.9885 | |
| GSE77861 | XIAP | 331 | 225858_s_at | 0.3559 | 0.1831 | |
| GSE97050 | XIAP | 331 | A_33_P3246990 | -0.1318 | 0.6209 | |
| SRP007169 | XIAP | 331 | RNAseq | -1.0207 | 0.0175 | |
| SRP008496 | XIAP | 331 | RNAseq | -0.5984 | 0.0234 | |
| SRP064894 | XIAP | 331 | RNAseq | -0.1770 | 0.4183 | |
| SRP133303 | XIAP | 331 | RNAseq | 0.3908 | 0.0179 | |
| SRP159526 | XIAP | 331 | RNAseq | -0.2149 | 0.4421 | |
| SRP193095 | XIAP | 331 | RNAseq | -0.2828 | 0.0033 | |
| SRP219564 | XIAP | 331 | RNAseq | -0.0918 | 0.7826 | |
| TCGA | XIAP | 331 | RNAseq | -0.0129 | 0.7831 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by XIAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XIAP:
No record found for this gene.
Somatic mutations of XIAP:
Generating mutation plots.
Highly correlated genes for XIAP:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XIAP | FAF2 | 0.787588 | 3 | 0 | 3 |
| XIAP | CBLC | 0.758065 | 4 | 0 | 4 |
| XIAP | N4BP1 | 0.734223 | 4 | 0 | 4 |
| XIAP | PET117 | 0.723528 | 3 | 0 | 3 |
| XIAP | C8orf76 | 0.722456 | 3 | 0 | 3 |
| XIAP | HUS1 | 0.721101 | 3 | 0 | 3 |
| XIAP | ITGB8 | 0.704081 | 5 | 0 | 5 |
| XIAP | FLVCR1 | 0.699021 | 3 | 0 | 3 |
| XIAP | PTPN4 | 0.693153 | 3 | 0 | 3 |
| XIAP | SLC9A6 | 0.692392 | 3 | 0 | 3 |
| XIAP | SMC5 | 0.692239 | 3 | 0 | 3 |
| XIAP | DHX33 | 0.689384 | 3 | 0 | 3 |
| XIAP | MARVELD2 | 0.685985 | 3 | 0 | 3 |
| XIAP | ZNF319 | 0.681242 | 3 | 0 | 3 |
| XIAP | CDC42SE1 | 0.680951 | 6 | 0 | 6 |
| XIAP | SERPINB9 | 0.680228 | 4 | 0 | 3 |
| XIAP | ARHGAP18 | 0.678427 | 3 | 0 | 3 |
| XIAP | ACBD3 | 0.675507 | 4 | 0 | 4 |
| XIAP | ADAM10 | 0.670912 | 4 | 0 | 4 |
| XIAP | CHD1 | 0.670743 | 3 | 0 | 3 |
For details and further investigation, click here
