| Full name: phosphoserine phosphatase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p11.2 | ||
| Entrez ID: 5723 | HGNC ID: HGNC:9577 | Ensembl Gene: ENSG00000146733 | OMIM ID: 172480 |
| Drug and gene relationship at DGIdb | |||
Expression of PSPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSPH | 5723 | 205194_at | 0.4086 | 0.7003 | |
| GSE20347 | PSPH | 5723 | 205194_at | 0.8723 | 0.0070 | |
| GSE23400 | PSPH | 5723 | 205194_at | 0.5101 | 0.0000 | |
| GSE26886 | PSPH | 5723 | 205194_at | 0.2677 | 0.1676 | |
| GSE29001 | PSPH | 5723 | 205194_at | 0.7499 | 0.0638 | |
| GSE38129 | PSPH | 5723 | 205194_at | 1.2078 | 0.0000 | |
| GSE45670 | PSPH | 5723 | 205194_at | 1.0825 | 0.0000 | |
| GSE53622 | PSPH | 5723 | 5876 | 0.9467 | 0.0000 | |
| GSE53624 | PSPH | 5723 | 5876 | 1.0415 | 0.0000 | |
| GSE63941 | PSPH | 5723 | 205194_at | 1.6964 | 0.0527 | |
| GSE77861 | PSPH | 5723 | 205194_at | -0.0450 | 0.9068 | |
| GSE97050 | PSPH | 5723 | A_32_P78816 | 0.5169 | 0.1138 | |
| SRP007169 | PSPH | 5723 | RNAseq | 0.8240 | 0.2208 | |
| SRP008496 | PSPH | 5723 | RNAseq | 1.2669 | 0.0061 | |
| SRP064894 | PSPH | 5723 | RNAseq | 1.1168 | 0.0006 | |
| SRP133303 | PSPH | 5723 | RNAseq | 0.5060 | 0.0539 | |
| SRP159526 | PSPH | 5723 | RNAseq | 1.0812 | 0.0478 | |
| SRP193095 | PSPH | 5723 | RNAseq | -0.0293 | 0.8866 | |
| SRP219564 | PSPH | 5723 | RNAseq | 0.7497 | 0.0849 | |
| TCGA | PSPH | 5723 | RNAseq | 0.3302 | 0.0007 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by PSPH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSPH | 5723 | 13 | 0 | 17 | |
| GSE20123 | PSPH | 5723 | 11 | 0 | 19 | |
| GSE43470 | PSPH | 5723 | 5 | 0 | 38 | |
| GSE46452 | PSPH | 5723 | 13 | 0 | 46 | |
| GSE47630 | PSPH | 5723 | 10 | 1 | 29 | |
| GSE54993 | PSPH | 5723 | 0 | 8 | 62 | |
| GSE54994 | PSPH | 5723 | 16 | 2 | 35 | |
| GSE60625 | PSPH | 5723 | 0 | 0 | 11 | |
| GSE74703 | PSPH | 5723 | 5 | 0 | 31 | |
| GSE74704 | PSPH | 5723 | 6 | 0 | 14 | |
| TCGA | PSPH | 5723 | 54 | 6 | 36 |
Total number of gains: 133; Total number of losses: 17; Total Number of normals: 338.
Somatic mutations of PSPH:
Generating mutation plots.
Highly correlated genes for PSPH:
Showing top 20/566 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSPH | KREMEN1 | 0.734239 | 3 | 0 | 3 |
| PSPH | IL36G | 0.712803 | 3 | 0 | 3 |
| PSPH | RAB38 | 0.69726 | 3 | 0 | 3 |
| PSPH | PPP2R2C | 0.690315 | 3 | 0 | 3 |
| PSPH | TYW5 | 0.670431 | 3 | 0 | 3 |
| PSPH | CCT6A | 0.666653 | 10 | 0 | 9 |
| PSPH | PLA2G4A | 0.666345 | 3 | 0 | 3 |
| PSPH | SLC6A14 | 0.650473 | 4 | 0 | 4 |
| PSPH | SESN3 | 0.645243 | 3 | 0 | 3 |
| PSPH | ZDHHC16 | 0.637943 | 5 | 0 | 5 |
| PSPH | TRIB3 | 0.637878 | 5 | 0 | 4 |
| PSPH | HMMR | 0.635489 | 9 | 0 | 8 |
| PSPH | ZBTB8OS | 0.632163 | 4 | 0 | 4 |
| PSPH | MRPS17 | 0.631157 | 8 | 0 | 7 |
| PSPH | CEP19 | 0.629839 | 4 | 0 | 4 |
| PSPH | HORMAD1 | 0.627836 | 3 | 0 | 3 |
| PSPH | DTL | 0.625986 | 9 | 0 | 9 |
| PSPH | AJUBA | 0.623238 | 5 | 0 | 4 |
| PSPH | CENPL | 0.616005 | 6 | 0 | 4 |
| PSPH | FANCB | 0.614464 | 4 | 0 | 4 |
For details and further investigation, click here
