| Full name: S100 calcium binding protein A2 | Alias Symbol: CAN19 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6273 | HGNC ID: HGNC:10492 | Ensembl Gene: ENSG00000196754 | OMIM ID: 176993 |
| Drug and gene relationship at DGIdb | |||
Expression of S100A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | S100A2 | 6273 | 204268_at | -0.1383 | 0.8044 | |
| GSE20347 | S100A2 | 6273 | 204268_at | -0.4362 | 0.0814 | |
| GSE23400 | S100A2 | 6273 | 204268_at | -0.0514 | 0.7576 | |
| GSE26886 | S100A2 | 6273 | 204268_at | -0.8998 | 0.1301 | |
| GSE29001 | S100A2 | 6273 | 204268_at | -0.8032 | 0.0610 | |
| GSE38129 | S100A2 | 6273 | 204268_at | 0.7581 | 0.2543 | |
| GSE45670 | S100A2 | 6273 | 204268_at | 0.3503 | 0.0001 | |
| GSE53622 | S100A2 | 6273 | 107258 | 0.1146 | 0.6434 | |
| GSE53624 | S100A2 | 6273 | 107258 | -0.0006 | 0.9966 | |
| GSE63941 | S100A2 | 6273 | 204268_at | 5.7744 | 0.0006 | |
| GSE77861 | S100A2 | 6273 | 204268_at | -0.0187 | 0.9432 | |
| GSE97050 | S100A2 | 6273 | A_33_P3376249 | 1.4361 | 0.3051 | |
| SRP007169 | S100A2 | 6273 | RNAseq | -1.4067 | 0.0010 | |
| SRP008496 | S100A2 | 6273 | RNAseq | -1.2670 | 0.0000 | |
| SRP064894 | S100A2 | 6273 | RNAseq | -0.5587 | 0.2193 | |
| SRP133303 | S100A2 | 6273 | RNAseq | 0.6527 | 0.0821 | |
| SRP159526 | S100A2 | 6273 | RNAseq | -1.1534 | 0.1525 | |
| SRP219564 | S100A2 | 6273 | RNAseq | -0.0410 | 0.9735 | |
| TCGA | S100A2 | 6273 | RNAseq | 1.4477 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by S100A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of S100A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | S100A2 | 6273 | 14 | 0 | 16 | |
| GSE20123 | S100A2 | 6273 | 14 | 0 | 16 | |
| GSE43470 | S100A2 | 6273 | 7 | 2 | 34 | |
| GSE46452 | S100A2 | 6273 | 2 | 1 | 56 | |
| GSE47630 | S100A2 | 6273 | 15 | 0 | 25 | |
| GSE54993 | S100A2 | 6273 | 0 | 4 | 66 | |
| GSE54994 | S100A2 | 6273 | 16 | 0 | 37 | |
| GSE60625 | S100A2 | 6273 | 0 | 0 | 11 | |
| GSE74703 | S100A2 | 6273 | 6 | 1 | 29 | |
| GSE74704 | S100A2 | 6273 | 7 | 0 | 13 | |
| TCGA | S100A2 | 6273 | 39 | 1 | 56 |
Total number of gains: 120; Total number of losses: 9; Total Number of normals: 359.
Somatic mutations of S100A2:
Generating mutation plots.
Highly correlated genes for S100A2:
Showing top 20/411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| S100A2 | SFN | 0.779332 | 12 | 0 | 12 |
| S100A2 | IRX2 | 0.733081 | 3 | 0 | 3 |
| S100A2 | KRT6A | 0.731357 | 12 | 0 | 11 |
| S100A2 | SERPINB5 | 0.705405 | 12 | 0 | 10 |
| S100A2 | ANXA2 | 0.7042 | 9 | 0 | 9 |
| S100A2 | KRT6C | 0.703551 | 4 | 0 | 3 |
| S100A2 | S100A11 | 0.699986 | 10 | 0 | 8 |
| S100A2 | KLC3 | 0.699763 | 4 | 0 | 4 |
| S100A2 | AGAP2-AS1 | 0.696567 | 4 | 0 | 4 |
| S100A2 | GJB3 | 0.696345 | 11 | 0 | 11 |
| S100A2 | KRT6B | 0.692979 | 12 | 0 | 10 |
| S100A2 | CDH3 | 0.692808 | 6 | 0 | 6 |
| S100A2 | FAM83A | 0.691912 | 7 | 0 | 7 |
| S100A2 | SDC1 | 0.687164 | 9 | 0 | 8 |
| S100A2 | PKP1 | 0.684251 | 10 | 0 | 8 |
| S100A2 | MYBL2 | 0.678748 | 3 | 0 | 3 |
| S100A2 | KRT5 | 0.675625 | 10 | 0 | 8 |
| S100A2 | KRT17 | 0.675529 | 4 | 0 | 4 |
| S100A2 | JUP | 0.675513 | 10 | 0 | 7 |
| S100A2 | RAB38 | 0.674971 | 12 | 0 | 10 |
For details and further investigation, click here
