| Full name: ceramide synthase 3 | Alias Symbol: MGC27091 | ||
| Type: protein-coding gene | Cytoband: 15q26.3 | ||
| Entrez ID: 204219 | HGNC ID: HGNC:23752 | Ensembl Gene: ENSG00000154227 | OMIM ID: 615276 |
Expression of CERS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CERS3 | 204219 | 1554253_a_at | -0.8906 | 0.5926 | |
| GSE26886 | CERS3 | 204219 | 1554253_a_at | -3.1419 | 0.0000 | |
| GSE45670 | CERS3 | 204219 | 1554252_a_at | -0.0052 | 0.9839 | |
| GSE53622 | CERS3 | 204219 | 87391 | -0.7068 | 0.0066 | |
| GSE53624 | CERS3 | 204219 | 87391 | -1.2574 | 0.0000 | |
| GSE63941 | CERS3 | 204219 | 1554253_a_at | 0.2599 | 0.5622 | |
| GSE77861 | CERS3 | 204219 | 1554253_a_at | -1.1382 | 0.0353 | |
| GSE97050 | CERS3 | 204219 | A_33_P3408305 | 0.3006 | 0.6013 | |
| SRP007169 | CERS3 | 204219 | RNAseq | -2.4973 | 0.0000 | |
| SRP008496 | CERS3 | 204219 | RNAseq | -2.1743 | 0.0000 | |
| SRP064894 | CERS3 | 204219 | RNAseq | -1.4468 | 0.0012 | |
| SRP133303 | CERS3 | 204219 | RNAseq | -1.2166 | 0.0001 | |
| SRP159526 | CERS3 | 204219 | RNAseq | -1.3247 | 0.0990 | |
| SRP219564 | CERS3 | 204219 | RNAseq | -1.8835 | 0.1188 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by CERS3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CERS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CERS3 | 204219 | 7 | 2 | 21 | |
| GSE20123 | CERS3 | 204219 | 7 | 2 | 21 | |
| GSE43470 | CERS3 | 204219 | 6 | 5 | 32 | |
| GSE46452 | CERS3 | 204219 | 3 | 7 | 49 | |
| GSE47630 | CERS3 | 204219 | 9 | 10 | 21 | |
| GSE54993 | CERS3 | 204219 | 4 | 7 | 59 | |
| GSE54994 | CERS3 | 204219 | 8 | 7 | 38 | |
| GSE60625 | CERS3 | 204219 | 4 | 0 | 7 | |
| GSE74703 | CERS3 | 204219 | 5 | 4 | 27 | |
| GSE74704 | CERS3 | 204219 | 3 | 3 | 14 | |
| TCGA | CERS3 | 204219 | 18 | 12 | 66 |
Total number of gains: 74; Total number of losses: 59; Total Number of normals: 355.
Somatic mutations of CERS3:
Generating mutation plots.
Highly correlated genes for CERS3:
Showing top 20/1396 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CERS3 | MPZL2 | 0.816711 | 7 | 0 | 7 |
| CERS3 | KRT80 | 0.796463 | 5 | 0 | 5 |
| CERS3 | NIPAL1 | 0.796174 | 3 | 0 | 3 |
| CERS3 | SERPINB3 | 0.787096 | 4 | 0 | 4 |
| CERS3 | TGM3 | 0.786403 | 5 | 0 | 5 |
| CERS3 | TMEM45B | 0.783108 | 6 | 0 | 6 |
| CERS3 | TGM1 | 0.782118 | 7 | 0 | 6 |
| CERS3 | CRCT1 | 0.779187 | 5 | 0 | 5 |
| CERS3 | DSG3 | 0.775692 | 7 | 0 | 7 |
| CERS3 | NUAK2 | 0.773236 | 3 | 0 | 3 |
| CERS3 | SERPINB4 | 0.770557 | 6 | 0 | 6 |
| CERS3 | SLC16A14 | 0.76825 | 3 | 0 | 3 |
| CERS3 | SIAH2 | 0.767734 | 3 | 0 | 3 |
| CERS3 | RETSAT | 0.763472 | 4 | 0 | 4 |
| CERS3 | SH3PXD2A-AS1 | 0.763142 | 3 | 0 | 3 |
| CERS3 | BTBD11 | 0.760521 | 7 | 0 | 7 |
| CERS3 | SLURP1 | 0.75898 | 6 | 0 | 6 |
| CERS3 | PRRG4 | 0.75897 | 7 | 0 | 6 |
| CERS3 | PGM2 | 0.756264 | 7 | 0 | 7 |
| CERS3 | ARAP2 | 0.755518 | 3 | 0 | 3 |
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