| Full name: ralA binding protein 1 | Alias Symbol: RLIP76|RIP1|RIP | ||
| Type: protein-coding gene | Cytoband: 18p11.22 | ||
| Entrez ID: 10928 | HGNC ID: HGNC:9841 | Ensembl Gene: ENSG00000017797 | OMIM ID: 605801 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
RALBP1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04014 | Ras signaling pathway | |
| hsa05200 | Pathways in cancer | |
| hsa05212 | Pancreatic cancer |
Expression of RALBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RALBP1 | 10928 | 202845_s_at | -0.1249 | 0.8845 | |
| GSE20347 | RALBP1 | 10928 | 202845_s_at | -0.4324 | 0.0052 | |
| GSE23400 | RALBP1 | 10928 | 202845_s_at | -0.2591 | 0.0021 | |
| GSE26886 | RALBP1 | 10928 | 202845_s_at | -1.2262 | 0.0000 | |
| GSE29001 | RALBP1 | 10928 | 202845_s_at | -0.1931 | 0.4717 | |
| GSE38129 | RALBP1 | 10928 | 202844_s_at | -0.4343 | 0.0123 | |
| GSE45670 | RALBP1 | 10928 | 202845_s_at | -0.0750 | 0.7105 | |
| GSE53622 | RALBP1 | 10928 | 130273 | -0.4259 | 0.0000 | |
| GSE53624 | RALBP1 | 10928 | 130273 | -0.3797 | 0.0000 | |
| GSE63941 | RALBP1 | 10928 | 202845_s_at | -0.0766 | 0.9091 | |
| GSE77861 | RALBP1 | 10928 | 202845_s_at | -0.2382 | 0.1482 | |
| GSE97050 | RALBP1 | 10928 | A_23_P376599 | -0.4727 | 0.1470 | |
| SRP007169 | RALBP1 | 10928 | RNAseq | -0.3917 | 0.3279 | |
| SRP008496 | RALBP1 | 10928 | RNAseq | -0.4666 | 0.1387 | |
| SRP064894 | RALBP1 | 10928 | RNAseq | -0.4311 | 0.0097 | |
| SRP133303 | RALBP1 | 10928 | RNAseq | -0.3597 | 0.0087 | |
| SRP159526 | RALBP1 | 10928 | RNAseq | -0.2592 | 0.2558 | |
| SRP193095 | RALBP1 | 10928 | RNAseq | -0.6452 | 0.0000 | |
| SRP219564 | RALBP1 | 10928 | RNAseq | -0.9342 | 0.0005 | |
| TCGA | RALBP1 | 10928 | RNAseq | 0.0275 | 0.5727 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RALBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RALBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RALBP1 | 10928 | 6 | 3 | 21 | |
| GSE20123 | RALBP1 | 10928 | 6 | 3 | 21 | |
| GSE43470 | RALBP1 | 10928 | 3 | 6 | 34 | |
| GSE46452 | RALBP1 | 10928 | 3 | 21 | 35 | |
| GSE47630 | RALBP1 | 10928 | 7 | 17 | 16 | |
| GSE54993 | RALBP1 | 10928 | 6 | 2 | 62 | |
| GSE54994 | RALBP1 | 10928 | 8 | 8 | 37 | |
| GSE60625 | RALBP1 | 10928 | 0 | 4 | 7 | |
| GSE74703 | RALBP1 | 10928 | 2 | 4 | 30 | |
| GSE74704 | RALBP1 | 10928 | 4 | 2 | 14 | |
| TCGA | RALBP1 | 10928 | 29 | 23 | 44 |
Total number of gains: 74; Total number of losses: 93; Total Number of normals: 321.
Somatic mutations of RALBP1:
Generating mutation plots.
Highly correlated genes for RALBP1:
Showing top 20/696 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RALBP1 | RTN3 | 0.743371 | 3 | 0 | 3 |
| RALBP1 | ACBD3 | 0.724606 | 3 | 0 | 3 |
| RALBP1 | PPP1R21 | 0.713639 | 3 | 0 | 3 |
| RALBP1 | ZFP3 | 0.711577 | 3 | 0 | 3 |
| RALBP1 | ANKRD37 | 0.708003 | 3 | 0 | 3 |
| RALBP1 | COX15 | 0.704036 | 3 | 0 | 3 |
| RALBP1 | DPY30 | 0.702371 | 3 | 0 | 3 |
| RALBP1 | OXNAD1 | 0.70156 | 3 | 0 | 3 |
| RALBP1 | PRDM10 | 0.697149 | 3 | 0 | 3 |
| RALBP1 | ZCCHC9 | 0.696499 | 4 | 0 | 3 |
| RALBP1 | RAB2A | 0.693408 | 4 | 0 | 3 |
| RALBP1 | CDK9 | 0.693194 | 3 | 0 | 3 |
| RALBP1 | ECH1 | 0.681541 | 3 | 0 | 3 |
| RALBP1 | ABCG2 | 0.681289 | 3 | 0 | 3 |
| RALBP1 | UBE4B | 0.680656 | 3 | 0 | 3 |
| RALBP1 | TMEM167A | 0.680115 | 3 | 0 | 3 |
| RALBP1 | BAG6 | 0.679848 | 3 | 0 | 3 |
| RALBP1 | PPIP5K2 | 0.679046 | 3 | 0 | 3 |
| RALBP1 | GBE1 | 0.676707 | 4 | 0 | 3 |
| RALBP1 | RBM7 | 0.67472 | 3 | 0 | 3 |
For details and further investigation, click here
