| Full name: RNA terminal phosphate cyclase like 1 | Alias Symbol: RPCL1|RNAC | ||
| Type: protein-coding gene | Cytoband: 9p24.1 | ||
| Entrez ID: 10171 | HGNC ID: HGNC:17687 | Ensembl Gene: ENSG00000120158 | OMIM ID: 611405 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RCL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RCL1 | 10171 | 218544_s_at | 0.3420 | 0.4080 | |
| GSE20347 | RCL1 | 10171 | 218544_s_at | 0.0607 | 0.4341 | |
| GSE23400 | RCL1 | 10171 | 218544_s_at | 0.1013 | 0.0261 | |
| GSE26886 | RCL1 | 10171 | 218544_s_at | 0.1123 | 0.4155 | |
| GSE29001 | RCL1 | 10171 | 218544_s_at | 0.0231 | 0.9318 | |
| GSE38129 | RCL1 | 10171 | 218544_s_at | 0.0442 | 0.6847 | |
| GSE45670 | RCL1 | 10171 | 218544_s_at | 0.0442 | 0.7454 | |
| GSE53622 | RCL1 | 10171 | 15194 | 0.2519 | 0.0019 | |
| GSE53624 | RCL1 | 10171 | 15194 | 0.5218 | 0.0000 | |
| GSE63941 | RCL1 | 10171 | 218544_s_at | 0.3946 | 0.4910 | |
| GSE77861 | RCL1 | 10171 | 218544_s_at | -0.0655 | 0.6809 | |
| GSE97050 | RCL1 | 10171 | A_23_P9152 | 0.0933 | 0.6203 | |
| SRP007169 | RCL1 | 10171 | RNAseq | 0.0989 | 0.8475 | |
| SRP008496 | RCL1 | 10171 | RNAseq | -0.0566 | 0.8675 | |
| SRP064894 | RCL1 | 10171 | RNAseq | 0.3670 | 0.0542 | |
| SRP133303 | RCL1 | 10171 | RNAseq | -0.0675 | 0.6110 | |
| SRP159526 | RCL1 | 10171 | RNAseq | -0.4299 | 0.1612 | |
| SRP193095 | RCL1 | 10171 | RNAseq | -0.2266 | 0.0495 | |
| SRP219564 | RCL1 | 10171 | RNAseq | -0.0365 | 0.9059 | |
| TCGA | RCL1 | 10171 | RNAseq | 0.1255 | 0.0703 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RCL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RCL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RCL1 | 10171 | 1 | 17 | 12 | |
| GSE20123 | RCL1 | 10171 | 1 | 16 | 13 | |
| GSE43470 | RCL1 | 10171 | 5 | 11 | 27 | |
| GSE46452 | RCL1 | 10171 | 2 | 23 | 34 | |
| GSE47630 | RCL1 | 10171 | 5 | 26 | 9 | |
| GSE54993 | RCL1 | 10171 | 6 | 3 | 61 | |
| GSE54994 | RCL1 | 10171 | 9 | 17 | 27 | |
| GSE60625 | RCL1 | 10171 | 0 | 2 | 9 | |
| GSE74703 | RCL1 | 10171 | 5 | 8 | 23 | |
| GSE74704 | RCL1 | 10171 | 0 | 12 | 8 | |
| TCGA | RCL1 | 10171 | 14 | 50 | 32 |
Total number of gains: 48; Total number of losses: 185; Total Number of normals: 255.
Somatic mutations of RCL1:
Generating mutation plots.
Highly correlated genes for RCL1:
Showing top 20/145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RCL1 | ANGEL2 | 0.715958 | 3 | 0 | 3 |
| RCL1 | EXOSC3 | 0.700408 | 6 | 0 | 6 |
| RCL1 | ZNF789 | 0.693921 | 3 | 0 | 3 |
| RCL1 | MON1A | 0.680777 | 3 | 0 | 3 |
| RCL1 | GPATCH1 | 0.671932 | 3 | 0 | 3 |
| RCL1 | SLC29A3 | 0.666867 | 4 | 0 | 3 |
| RCL1 | MCM3AP | 0.665932 | 3 | 0 | 3 |
| RCL1 | PSIP1 | 0.665147 | 3 | 0 | 3 |
| RCL1 | AMMECR1L | 0.662196 | 3 | 0 | 3 |
| RCL1 | MRPS9 | 0.648678 | 4 | 0 | 3 |
| RCL1 | MOB3C | 0.647454 | 3 | 0 | 3 |
| RCL1 | ATR | 0.64571 | 3 | 0 | 3 |
| RCL1 | MED12 | 0.642064 | 3 | 0 | 3 |
| RCL1 | RASIP1 | 0.640322 | 3 | 0 | 3 |
| RCL1 | TDP2 | 0.635923 | 4 | 0 | 3 |
| RCL1 | RRP36 | 0.635443 | 4 | 0 | 3 |
| RCL1 | UHRF2 | 0.632965 | 5 | 0 | 3 |
| RCL1 | ZCCHC2 | 0.630608 | 5 | 0 | 4 |
| RCL1 | NVL | 0.630477 | 4 | 0 | 3 |
| RCL1 | HSPB11 | 0.630212 | 4 | 0 | 3 |
For details and further investigation, click here
