| Full name: MOB kinase activator 3C | Alias Symbol: MOB1E | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 148932 | HGNC ID: HGNC:29800 | Ensembl Gene: ENSG00000142961 | OMIM ID: |
Expression of MOB3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOB3C | 148932 | 227066_at | 0.5403 | 0.0869 | |
| GSE26886 | MOB3C | 148932 | 227066_at | 0.3985 | 0.1666 | |
| GSE45670 | MOB3C | 148932 | 227066_at | 0.2890 | 0.1221 | |
| GSE53622 | MOB3C | 148932 | 8677 | -1.1510 | 0.0000 | |
| GSE53624 | MOB3C | 148932 | 8677 | -1.5179 | 0.0000 | |
| GSE63941 | MOB3C | 148932 | 227066_at | 0.0038 | 0.9953 | |
| GSE77861 | MOB3C | 148932 | 227066_at | 0.3638 | 0.1966 | |
| GSE97050 | MOB3C | 148932 | A_23_P166 | -0.1231 | 0.6602 | |
| SRP007169 | MOB3C | 148932 | RNAseq | 0.8601 | 0.0562 | |
| SRP008496 | MOB3C | 148932 | RNAseq | 0.7881 | 0.0120 | |
| SRP064894 | MOB3C | 148932 | RNAseq | 0.3070 | 0.0275 | |
| SRP133303 | MOB3C | 148932 | RNAseq | 0.1485 | 0.2592 | |
| SRP159526 | MOB3C | 148932 | RNAseq | 0.4701 | 0.3072 | |
| SRP193095 | MOB3C | 148932 | RNAseq | 0.3754 | 0.0059 | |
| SRP219564 | MOB3C | 148932 | RNAseq | 0.2815 | 0.4601 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MOB3C expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MOB3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOB3C | 148932 | 4 | 3 | 23 | |
| GSE20123 | MOB3C | 148932 | 4 | 2 | 24 | |
| GSE43470 | MOB3C | 148932 | 5 | 1 | 37 | |
| GSE46452 | MOB3C | 148932 | 2 | 1 | 56 | |
| GSE47630 | MOB3C | 148932 | 8 | 4 | 28 | |
| GSE54993 | MOB3C | 148932 | 0 | 1 | 69 | |
| GSE54994 | MOB3C | 148932 | 11 | 2 | 40 | |
| GSE60625 | MOB3C | 148932 | 0 | 0 | 11 | |
| GSE74703 | MOB3C | 148932 | 4 | 1 | 31 | |
| GSE74704 | MOB3C | 148932 | 2 | 0 | 18 | |
| TCGA | MOB3C | 148932 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of MOB3C:
Generating mutation plots.
Highly correlated genes for MOB3C:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOB3C | RGS14 | 0.873252 | 3 | 0 | 3 |
| MOB3C | BAK1 | 0.851633 | 3 | 0 | 3 |
| MOB3C | AP2M1 | 0.808785 | 3 | 0 | 3 |
| MOB3C | KCTD2 | 0.798592 | 3 | 0 | 3 |
| MOB3C | PIGU | 0.7932 | 3 | 0 | 3 |
| MOB3C | RUNDC1 | 0.785015 | 4 | 0 | 4 |
| MOB3C | MRPS5 | 0.782636 | 3 | 0 | 3 |
| MOB3C | ZNF764 | 0.770468 | 3 | 0 | 3 |
| MOB3C | U2AF1 | 0.769979 | 4 | 0 | 4 |
| MOB3C | PXMP2 | 0.766451 | 4 | 0 | 4 |
| MOB3C | RFNG | 0.756822 | 3 | 0 | 3 |
| MOB3C | MTOR | 0.75627 | 3 | 0 | 3 |
| MOB3C | SLC25A1 | 0.755156 | 3 | 0 | 3 |
| MOB3C | MAK16 | 0.753031 | 3 | 0 | 3 |
| MOB3C | PSMC3 | 0.752105 | 3 | 0 | 3 |
| MOB3C | LGALSL | 0.751749 | 3 | 0 | 3 |
| MOB3C | NAP1L4 | 0.750276 | 4 | 0 | 4 |
| MOB3C | HIC2 | 0.749999 | 4 | 0 | 3 |
| MOB3C | TRPM4 | 0.749382 | 3 | 0 | 3 |
| MOB3C | DDX28 | 0.748063 | 3 | 0 | 3 |
For details and further investigation, click here
