SLC29A3

 

Full name: solute carrier family 29 member 3 Alias Symbol: ENT3|FLJ11160
Type: protein-coding gene Cytoband: 10q22.1
Entrez ID: 55315 HGNC ID: HGNC:23096 Ensembl Gene: ENSG00000198246 OMIM ID: 612373
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of SLC29A3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC29A3 55315 219344_at 0.2590 0.5213
GSE20347 SLC29A3 55315 219344_at 0.1853 0.0579
GSE23400 SLC29A3 55315 219344_at -0.1320 0.0021
GSE26886 SLC29A3 55315 219344_at 0.3358 0.0263
GSE29001 SLC29A3 55315 219344_at -0.1539 0.3296
GSE38129 SLC29A3 55315 219344_at 0.1317 0.1602
GSE45670 SLC29A3 55315 219344_at -0.0192 0.8870
GSE53622 SLC29A3 55315 47865 0.6658 0.0000
GSE53624 SLC29A3 55315 47865 0.6248 0.0000
GSE63941 SLC29A3 55315 219344_at 0.2513 0.7383
GSE77861 SLC29A3 55315 219344_at -0.1366 0.2756
GSE97050 SLC29A3 55315 A_23_P46871 0.5484 0.1403
SRP007169 SLC29A3 55315 RNAseq 0.4723 0.5732
SRP064894 SLC29A3 55315 RNAseq 1.2218 0.0009
SRP133303 SLC29A3 55315 RNAseq 0.8079 0.0005
SRP159526 SLC29A3 55315 RNAseq 0.7288 0.0647
SRP193095 SLC29A3 55315 RNAseq 0.4567 0.0400
SRP219564 SLC29A3 55315 RNAseq 0.6856 0.1147
TCGA SLC29A3 55315 RNAseq -0.1922 0.0687

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by SLC29A3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SLC29A3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC29A3 55315 2 4 24
GSE20123 SLC29A3 55315 2 3 25
GSE43470 SLC29A3 55315 1 8 34
GSE46452 SLC29A3 55315 0 11 48
GSE47630 SLC29A3 55315 2 14 24
GSE54993 SLC29A3 55315 7 0 63
GSE54994 SLC29A3 55315 2 11 40
GSE60625 SLC29A3 55315 0 0 11
GSE74703 SLC29A3 55315 1 5 30
GSE74704 SLC29A3 55315 1 1 18
TCGA SLC29A3 55315 11 23 62

Total number of gains: 29; Total number of losses: 80; Total Number of normals: 379.  


 

Somatic mutations of SLC29A3:

 

Generating mutation plots.

 

Highly correlated genes for SLC29A3:

 

Showing top 20/456 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC29A3TBCC0.801973303
SLC29A3ZNRD10.796444303
SLC29A3ZNF2870.79001303
SLC29A3SSBP40.785245303
SLC29A3SLC15A30.770579303
SLC29A3CRTC20.768937303
SLC29A3HSPBP10.762681303
SLC29A3ERP270.748556303
SLC29A3NSD10.74077303
SLC29A3GLIS30.727574403
SLC29A3UBASH3A0.722346303
SLC29A3YIPF30.714857403
SLC29A3PLCD30.713522303
SLC29A3ZNF7890.713349303
SLC29A3WDTC10.713104404
SLC29A3POC50.712837303
SLC29A3TTLL10.71278303
SLC29A3TMTC40.712153303
SLC29A3GNG30.711359303
SLC29A3LCP20.709389303

For details and further investigation, click here