| Full name: heat shock protein family B (small) member 11 | Alias Symbol: HSPCO34|PP25|IFT25 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 51668 | HGNC ID: HGNC:25019 | Ensembl Gene: ENSG00000081870 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HSPB11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPB11 | 51668 | 215691_x_at | 0.5096 | 0.1003 | |
| GSE20347 | HSPB11 | 51668 | 215691_x_at | 0.3815 | 0.0388 | |
| GSE23400 | HSPB11 | 51668 | 215691_x_at | 0.5762 | 0.0000 | |
| GSE26886 | HSPB11 | 51668 | 215691_x_at | 0.7193 | 0.0008 | |
| GSE29001 | HSPB11 | 51668 | 215691_x_at | 0.4664 | 0.0929 | |
| GSE38129 | HSPB11 | 51668 | 215691_x_at | 0.3841 | 0.0026 | |
| GSE45670 | HSPB11 | 51668 | 215691_x_at | 0.2500 | 0.1595 | |
| GSE53622 | HSPB11 | 51668 | 101501 | 0.2734 | 0.0000 | |
| GSE53624 | HSPB11 | 51668 | 101501 | 0.5207 | 0.0000 | |
| GSE63941 | HSPB11 | 51668 | 215691_x_at | 0.4337 | 0.4409 | |
| GSE77861 | HSPB11 | 51668 | 215691_x_at | -0.2397 | 0.3491 | |
| GSE97050 | HSPB11 | 51668 | A_23_P96872 | 0.1247 | 0.7388 | |
| SRP007169 | HSPB11 | 51668 | RNAseq | 0.1823 | 0.6329 | |
| SRP008496 | HSPB11 | 51668 | RNAseq | 0.2643 | 0.2879 | |
| SRP064894 | HSPB11 | 51668 | RNAseq | 0.6166 | 0.0196 | |
| SRP133303 | HSPB11 | 51668 | RNAseq | 0.5060 | 0.0050 | |
| SRP159526 | HSPB11 | 51668 | RNAseq | 0.0517 | 0.8750 | |
| SRP193095 | HSPB11 | 51668 | RNAseq | -0.1146 | 0.4378 | |
| SRP219564 | HSPB11 | 51668 | RNAseq | 0.3599 | 0.3363 | |
| TCGA | HSPB11 | 51668 | RNAseq | 0.1756 | 0.0079 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HSPB11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPB11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPB11 | 51668 | 3 | 4 | 23 | |
| GSE20123 | HSPB11 | 51668 | 3 | 3 | 24 | |
| GSE43470 | HSPB11 | 51668 | 6 | 2 | 35 | |
| GSE46452 | HSPB11 | 51668 | 2 | 1 | 56 | |
| GSE47630 | HSPB11 | 51668 | 8 | 4 | 28 | |
| GSE54993 | HSPB11 | 51668 | 0 | 0 | 70 | |
| GSE54994 | HSPB11 | 51668 | 10 | 2 | 41 | |
| GSE60625 | HSPB11 | 51668 | 0 | 0 | 11 | |
| GSE74703 | HSPB11 | 51668 | 4 | 1 | 31 | |
| GSE74704 | HSPB11 | 51668 | 2 | 0 | 18 | |
| TCGA | HSPB11 | 51668 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 35; Total Number of normals: 405.
Somatic mutations of HSPB11:
Generating mutation plots.
Highly correlated genes for HSPB11:
Showing top 20/1394 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPB11 | MMS19 | 0.823553 | 3 | 0 | 3 |
| HSPB11 | PET117 | 0.799637 | 3 | 0 | 3 |
| HSPB11 | BAG4 | 0.776418 | 3 | 0 | 3 |
| HSPB11 | DYRK2 | 0.771209 | 3 | 0 | 3 |
| HSPB11 | ZNF584 | 0.762536 | 3 | 0 | 3 |
| HSPB11 | GPR153 | 0.759265 | 4 | 0 | 4 |
| HSPB11 | KRR1 | 0.752128 | 3 | 0 | 3 |
| HSPB11 | MAGOH | 0.746784 | 3 | 0 | 3 |
| HSPB11 | KTI12 | 0.74498 | 3 | 0 | 3 |
| HSPB11 | PIGU | 0.74248 | 3 | 0 | 3 |
| HSPB11 | GPHN | 0.741754 | 3 | 0 | 3 |
| HSPB11 | UBA52 | 0.739851 | 3 | 0 | 3 |
| HSPB11 | ANXA7 | 0.739325 | 3 | 0 | 3 |
| HSPB11 | XAB2 | 0.734222 | 3 | 0 | 3 |
| HSPB11 | METTL23 | 0.725011 | 5 | 0 | 5 |
| HSPB11 | TDRD5 | 0.721456 | 3 | 0 | 3 |
| HSPB11 | ZC3HC1 | 0.721438 | 4 | 0 | 3 |
| HSPB11 | KHSRP | 0.720604 | 4 | 0 | 3 |
| HSPB11 | NACC1 | 0.719502 | 3 | 0 | 3 |
| HSPB11 | SSBP4 | 0.719145 | 3 | 0 | 3 |
For details and further investigation, click here
