| Full name: regulatory factor X4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 5992 | HGNC ID: HGNC:9985 | Ensembl Gene: ENSG00000111783 | OMIM ID: 603958 |
| Drug and gene relationship at DGIdb | |||
Expression of RFX4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFX4 | 5992 | 1552809_at | 0.1222 | 0.5862 | |
| GSE20347 | RFX4 | 5992 | 207672_at | 0.0155 | 0.8085 | |
| GSE23400 | RFX4 | 5992 | 207672_at | -0.0910 | 0.0002 | |
| GSE26886 | RFX4 | 5992 | 207672_at | -0.1396 | 0.1840 | |
| GSE29001 | RFX4 | 5992 | 207672_at | -0.0975 | 0.3712 | |
| GSE38129 | RFX4 | 5992 | 207672_at | -0.0286 | 0.6136 | |
| GSE45670 | RFX4 | 5992 | 1552809_at | -0.0857 | 0.4553 | |
| GSE53622 | RFX4 | 5992 | 26766 | -0.0822 | 0.6512 | |
| GSE53624 | RFX4 | 5992 | 26766 | 0.5082 | 0.0000 | |
| GSE63941 | RFX4 | 5992 | 1552809_at | -0.1966 | 0.1098 | |
| GSE77861 | RFX4 | 5992 | 1552809_at | -0.0278 | 0.7950 | |
| TCGA | RFX4 | 5992 | RNAseq | 1.7562 | 0.2160 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RFX4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFX4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFX4 | 5992 | 5 | 3 | 22 | |
| GSE20123 | RFX4 | 5992 | 5 | 3 | 22 | |
| GSE43470 | RFX4 | 5992 | 2 | 1 | 40 | |
| GSE46452 | RFX4 | 5992 | 9 | 1 | 49 | |
| GSE47630 | RFX4 | 5992 | 9 | 1 | 30 | |
| GSE54993 | RFX4 | 5992 | 0 | 5 | 65 | |
| GSE54994 | RFX4 | 5992 | 4 | 2 | 47 | |
| GSE60625 | RFX4 | 5992 | 0 | 0 | 11 | |
| GSE74703 | RFX4 | 5992 | 2 | 0 | 34 | |
| GSE74704 | RFX4 | 5992 | 2 | 2 | 16 | |
| TCGA | RFX4 | 5992 | 21 | 10 | 65 |
Total number of gains: 59; Total number of losses: 28; Total Number of normals: 401.
Somatic mutations of RFX4:
Generating mutation plots.
Highly correlated genes for RFX4:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFX4 | ZNF557 | 0.658397 | 3 | 0 | 3 |
| RFX4 | TBX19 | 0.656882 | 3 | 0 | 3 |
| RFX4 | JPX | 0.648639 | 3 | 0 | 3 |
| RFX4 | ATRNL1 | 0.637302 | 3 | 0 | 3 |
| RFX4 | SH3RF3-AS1 | 0.607426 | 3 | 0 | 3 |
| RFX4 | RPH3A | 0.6068 | 3 | 0 | 3 |
| RFX4 | FCAR | 0.604666 | 3 | 0 | 3 |
| RFX4 | USP29 | 0.596066 | 3 | 0 | 3 |
| RFX4 | ONECUT1 | 0.593911 | 3 | 0 | 3 |
| RFX4 | GOLGA6L6 | 0.592574 | 4 | 0 | 3 |
| RFX4 | OR9Q2 | 0.584575 | 3 | 0 | 3 |
| RFX4 | HIVEP3 | 0.58033 | 3 | 0 | 3 |
| RFX4 | SLC13A3 | 0.577295 | 4 | 0 | 3 |
| RFX4 | KCNQ1OT1 | 0.576438 | 4 | 0 | 3 |
| RFX4 | PSG1 | 0.573445 | 4 | 0 | 4 |
| RFX4 | ALPP | 0.571622 | 4 | 0 | 3 |
| RFX4 | USP49 | 0.567184 | 4 | 0 | 3 |
| RFX4 | TTLL2 | 0.566132 | 4 | 0 | 3 |
| RFX4 | ANKRD44-IT1 | 0.563152 | 3 | 0 | 3 |
| RFX4 | FGF23 | 0.56014 | 4 | 0 | 3 |
For details and further investigation, click here
