| Full name: zinc finger protein 557 | Alias Symbol: MGC4054 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 79230 | HGNC ID: HGNC:28632 | Ensembl Gene: ENSG00000130544 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF557:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF557 | 79230 | 220444_at | 0.4577 | 0.4456 | |
| GSE20347 | ZNF557 | 79230 | 220444_at | 0.0406 | 0.8288 | |
| GSE23400 | ZNF557 | 79230 | 220444_at | 0.0215 | 0.5681 | |
| GSE26886 | ZNF557 | 79230 | 220444_at | -0.4976 | 0.1656 | |
| GSE29001 | ZNF557 | 79230 | 220444_at | -0.0099 | 0.9836 | |
| GSE38129 | ZNF557 | 79230 | 220444_at | 0.1246 | 0.3884 | |
| GSE45670 | ZNF557 | 79230 | 220444_at | 0.6770 | 0.0010 | |
| GSE53622 | ZNF557 | 79230 | 65572 | -0.3115 | 0.0020 | |
| GSE53624 | ZNF557 | 79230 | 65572 | 0.0416 | 0.6541 | |
| GSE63941 | ZNF557 | 79230 | 220444_at | -0.5729 | 0.3834 | |
| GSE77861 | ZNF557 | 79230 | 220444_at | 0.0484 | 0.8090 | |
| GSE97050 | ZNF557 | 79230 | A_32_P177097 | -0.0545 | 0.8149 | |
| SRP007169 | ZNF557 | 79230 | RNAseq | 0.6908 | 0.0655 | |
| SRP008496 | ZNF557 | 79230 | RNAseq | 0.7143 | 0.0058 | |
| SRP064894 | ZNF557 | 79230 | RNAseq | 0.2442 | 0.0857 | |
| SRP133303 | ZNF557 | 79230 | RNAseq | -0.0841 | 0.5501 | |
| SRP159526 | ZNF557 | 79230 | RNAseq | -0.0758 | 0.7234 | |
| SRP193095 | ZNF557 | 79230 | RNAseq | -0.0104 | 0.8771 | |
| SRP219564 | ZNF557 | 79230 | RNAseq | 0.3854 | 0.1918 | |
| TCGA | ZNF557 | 79230 | RNAseq | -0.1169 | 0.1365 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF557 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF557:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF557 | 79230 | 5 | 3 | 22 | |
| GSE20123 | ZNF557 | 79230 | 4 | 2 | 24 | |
| GSE43470 | ZNF557 | 79230 | 2 | 6 | 35 | |
| GSE46452 | ZNF557 | 79230 | 47 | 1 | 11 | |
| GSE47630 | ZNF557 | 79230 | 5 | 7 | 28 | |
| GSE54993 | ZNF557 | 79230 | 16 | 3 | 51 | |
| GSE54994 | ZNF557 | 79230 | 6 | 14 | 33 | |
| GSE60625 | ZNF557 | 79230 | 9 | 0 | 2 | |
| GSE74703 | ZNF557 | 79230 | 2 | 4 | 30 | |
| GSE74704 | ZNF557 | 79230 | 1 | 2 | 17 | |
| TCGA | ZNF557 | 79230 | 8 | 21 | 67 |
Total number of gains: 105; Total number of losses: 63; Total Number of normals: 320.
Somatic mutations of ZNF557:
Generating mutation plots.
Highly correlated genes for ZNF557:
Showing top 20/251 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF557 | MBD4 | 0.871929 | 3 | 0 | 3 |
| ZNF557 | BLZF1 | 0.814509 | 3 | 0 | 3 |
| ZNF557 | TRIM56 | 0.767409 | 3 | 0 | 3 |
| ZNF557 | EIF3M | 0.761332 | 3 | 0 | 3 |
| ZNF557 | CREB1 | 0.760956 | 3 | 0 | 3 |
| ZNF557 | RPL7L1 | 0.757629 | 4 | 0 | 4 |
| ZNF557 | CAPRIN1 | 0.749941 | 3 | 0 | 3 |
| ZNF557 | TRMT61B | 0.745422 | 3 | 0 | 3 |
| ZNF557 | MMS19 | 0.742594 | 3 | 0 | 3 |
| ZNF557 | KLHL8 | 0.739167 | 3 | 0 | 3 |
| ZNF557 | STX6 | 0.734777 | 3 | 0 | 3 |
| ZNF557 | CDC73 | 0.726365 | 3 | 0 | 3 |
| ZNF557 | SRSF6 | 0.720177 | 3 | 0 | 3 |
| ZNF557 | KDM5B | 0.711756 | 4 | 0 | 4 |
| ZNF557 | CCDC90B | 0.711684 | 3 | 0 | 3 |
| ZNF557 | ZNF223 | 0.710757 | 4 | 0 | 4 |
| ZNF557 | PLEKHB2 | 0.710533 | 4 | 0 | 3 |
| ZNF557 | AKT1S1 | 0.710146 | 3 | 0 | 3 |
| ZNF557 | GAR1 | 0.707557 | 3 | 0 | 3 |
| ZNF557 | ZNF260 | 0.707338 | 4 | 0 | 3 |
For details and further investigation, click here
