| Full name: pregnancy specific beta-1-glycoprotein 1 | Alias Symbol: PSGGA|CD66f|PBG1 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 5669 | HGNC ID: HGNC:9514 | Ensembl Gene: ENSG00000231924 | OMIM ID: 176390 |
| Drug and gene relationship at DGIdb | |||
Expression of PSG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSG1 | 5669 | 208257_x_at | -0.2662 | 0.4575 | |
| GSE20347 | PSG1 | 5669 | 208257_x_at | -0.0915 | 0.4540 | |
| GSE23400 | PSG1 | 5669 | 208257_x_at | -0.3283 | 0.0000 | |
| GSE26886 | PSG1 | 5669 | 208257_x_at | -0.1187 | 0.5092 | |
| GSE29001 | PSG1 | 5669 | 208257_x_at | -0.2272 | 0.2288 | |
| GSE38129 | PSG1 | 5669 | 208257_x_at | -0.2357 | 0.0381 | |
| GSE45670 | PSG1 | 5669 | 208257_x_at | 0.1492 | 0.1818 | |
| GSE53622 | PSG1 | 5669 | 11332 | 0.1944 | 0.3775 | |
| GSE53624 | PSG1 | 5669 | 11332 | -0.0257 | 0.8988 | |
| GSE63941 | PSG1 | 5669 | 208257_x_at | 0.3449 | 0.6707 | |
| GSE77861 | PSG1 | 5669 | 208257_x_at | -0.1491 | 0.5209 | |
| TCGA | PSG1 | 5669 | RNAseq | 1.8419 | 0.3226 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSG1 | 5669 | 6 | 5 | 19 | |
| GSE20123 | PSG1 | 5669 | 5 | 4 | 21 | |
| GSE43470 | PSG1 | 5669 | 5 | 11 | 27 | |
| GSE46452 | PSG1 | 5669 | 46 | 1 | 12 | |
| GSE47630 | PSG1 | 5669 | 8 | 6 | 26 | |
| GSE54993 | PSG1 | 5669 | 17 | 4 | 49 | |
| GSE54994 | PSG1 | 5669 | 7 | 12 | 34 | |
| GSE60625 | PSG1 | 5669 | 9 | 0 | 2 | |
| GSE74703 | PSG1 | 5669 | 5 | 7 | 24 | |
| GSE74704 | PSG1 | 5669 | 4 | 2 | 14 | |
| TCGA | PSG1 | 5669 | 14 | 15 | 67 |
Total number of gains: 126; Total number of losses: 67; Total Number of normals: 295.
Somatic mutations of PSG1:
Generating mutation plots.
Highly correlated genes for PSG1:
Showing top 20/1194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSG1 | HLA-DOA | 0.722656 | 4 | 0 | 4 |
| PSG1 | PSG4 | 0.71711 | 11 | 0 | 10 |
| PSG1 | SLC22A13 | 0.714306 | 4 | 0 | 4 |
| PSG1 | MAP3K19 | 0.708369 | 7 | 0 | 7 |
| PSG1 | ITGA10 | 0.706086 | 6 | 0 | 6 |
| PSG1 | CCDC7 | 0.705228 | 4 | 0 | 4 |
| PSG1 | KRTAP5-9 | 0.703098 | 5 | 0 | 5 |
| PSG1 | CYP2A6 | 0.701978 | 6 | 0 | 5 |
| PSG1 | IFNA10 | 0.70079 | 5 | 0 | 5 |
| PSG1 | PSG7 | 0.698775 | 9 | 0 | 8 |
| PSG1 | OTOR | 0.695062 | 4 | 0 | 4 |
| PSG1 | SLC13A3 | 0.694898 | 5 | 0 | 5 |
| PSG1 | DAB1 | 0.689971 | 4 | 0 | 4 |
| PSG1 | UMOD | 0.686824 | 5 | 0 | 5 |
| PSG1 | PSG6 | 0.68671 | 7 | 0 | 6 |
| PSG1 | EDA2R | 0.684902 | 6 | 0 | 5 |
| PSG1 | GEMIN7 | 0.682643 | 4 | 0 | 4 |
| PSG1 | JAK3 | 0.680647 | 5 | 0 | 4 |
| PSG1 | CD244 | 0.680387 | 5 | 0 | 5 |
| PSG1 | ECE2 | 0.678952 | 4 | 0 | 4 |
For details and further investigation, click here
