| Full name: rabphilin 3A | Alias Symbol: KIAA0985|rabphilin|exophilin-1 | ||
| Type: protein-coding gene | Cytoband: 12q24.13 | ||
| Entrez ID: 22895 | HGNC ID: HGNC:17056 | Ensembl Gene: ENSG00000089169 | OMIM ID: 612159 |
| Drug and gene relationship at DGIdb | |||
Expression of RPH3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPH3A | 22895 | 205230_at | -0.0394 | 0.9282 | |
| GSE20347 | RPH3A | 22895 | 205230_at | -0.0914 | 0.0747 | |
| GSE23400 | RPH3A | 22895 | 205230_at | -0.0926 | 0.0020 | |
| GSE26886 | RPH3A | 22895 | 205230_at | -0.0841 | 0.4966 | |
| GSE29001 | RPH3A | 22895 | 205230_at | -0.1612 | 0.3543 | |
| GSE38129 | RPH3A | 22895 | 205230_at | -0.0933 | 0.0252 | |
| GSE45670 | RPH3A | 22895 | 205230_at | -0.0057 | 0.9365 | |
| GSE53622 | RPH3A | 22895 | 81680 | 0.1157 | 0.5340 | |
| GSE53624 | RPH3A | 22895 | 81680 | 0.1369 | 0.2121 | |
| GSE63941 | RPH3A | 22895 | 205230_at | 0.0417 | 0.8523 | |
| GSE77861 | RPH3A | 22895 | 205230_at | -0.0916 | 0.3712 | |
| GSE97050 | RPH3A | 22895 | A_33_P3395384 | -0.1842 | 0.4797 | |
| TCGA | RPH3A | 22895 | RNAseq | 0.3419 | 0.6112 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPH3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPH3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPH3A | 22895 | 4 | 3 | 23 | |
| GSE20123 | RPH3A | 22895 | 4 | 3 | 23 | |
| GSE43470 | RPH3A | 22895 | 2 | 0 | 41 | |
| GSE46452 | RPH3A | 22895 | 9 | 1 | 49 | |
| GSE47630 | RPH3A | 22895 | 9 | 3 | 28 | |
| GSE54993 | RPH3A | 22895 | 0 | 5 | 65 | |
| GSE54994 | RPH3A | 22895 | 4 | 2 | 47 | |
| GSE60625 | RPH3A | 22895 | 0 | 0 | 11 | |
| GSE74703 | RPH3A | 22895 | 2 | 0 | 34 | |
| GSE74704 | RPH3A | 22895 | 2 | 2 | 16 | |
| TCGA | RPH3A | 22895 | 22 | 11 | 63 |
Total number of gains: 58; Total number of losses: 30; Total Number of normals: 400.
Somatic mutations of RPH3A:
Generating mutation plots.
Highly correlated genes for RPH3A:
Showing top 20/465 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPH3A | NXNL1 | 0.788197 | 3 | 0 | 3 |
| RPH3A | ZMAT4 | 0.733706 | 3 | 0 | 3 |
| RPH3A | NRG3 | 0.726163 | 3 | 0 | 3 |
| RPH3A | SLC6A12 | 0.711133 | 3 | 0 | 3 |
| RPH3A | HSF4 | 0.709703 | 3 | 0 | 3 |
| RPH3A | RUNX1T1 | 0.704343 | 4 | 0 | 4 |
| RPH3A | CGA | 0.704207 | 4 | 0 | 4 |
| RPH3A | TUBB4A | 0.698714 | 6 | 0 | 6 |
| RPH3A | CLDN19 | 0.690949 | 3 | 0 | 3 |
| RPH3A | SEMA3B | 0.684115 | 3 | 0 | 3 |
| RPH3A | DAB1 | 0.677677 | 5 | 0 | 5 |
| RPH3A | LGALS12 | 0.677464 | 3 | 0 | 3 |
| RPH3A | STXBP6 | 0.675445 | 3 | 0 | 3 |
| RPH3A | DRD2 | 0.673512 | 6 | 0 | 6 |
| RPH3A | POM121L12 | 0.673449 | 3 | 0 | 3 |
| RPH3A | WNT9B | 0.672005 | 3 | 0 | 3 |
| RPH3A | OPRK1 | 0.664693 | 4 | 0 | 4 |
| RPH3A | HTR6 | 0.663662 | 4 | 0 | 3 |
| RPH3A | CALCA | 0.660057 | 5 | 0 | 4 |
| RPH3A | PKLR | 0.660031 | 4 | 0 | 4 |
For details and further investigation, click here
