| Full name: proline rich 12 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 57479 | HGNC ID: HGNC:29217 | Ensembl Gene: ENSG00000126464 | OMIM ID: 616633 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PRR12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR12 | 57479 | 226716_at | 0.4900 | 0.2245 | |
| GSE26886 | PRR12 | 57479 | 226716_at | 0.5219 | 0.0002 | |
| GSE45670 | PRR12 | 57479 | 226716_at | 0.0771 | 0.5392 | |
| GSE63941 | PRR12 | 57479 | 226716_at | -0.0017 | 0.9954 | |
| GSE77861 | PRR12 | 57479 | 226716_at | 0.0748 | 0.7150 | |
| GSE97050 | PRR12 | 57479 | A_23_P55948 | -0.1372 | 0.5429 | |
| SRP007169 | PRR12 | 57479 | RNAseq | 1.2855 | 0.0057 | |
| SRP008496 | PRR12 | 57479 | RNAseq | 0.7423 | 0.0263 | |
| SRP064894 | PRR12 | 57479 | RNAseq | 0.7216 | 0.0011 | |
| SRP133303 | PRR12 | 57479 | RNAseq | 0.1598 | 0.3515 | |
| SRP159526 | PRR12 | 57479 | RNAseq | 0.7509 | 0.0035 | |
| SRP193095 | PRR12 | 57479 | RNAseq | 0.5863 | 0.0052 | |
| SRP219564 | PRR12 | 57479 | RNAseq | 0.4169 | 0.0653 | |
| TCGA | PRR12 | 57479 | RNAseq | 0.0581 | 0.1937 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PRR12 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of PRR12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR12 | 57479 | 4 | 4 | 22 | |
| GSE20123 | PRR12 | 57479 | 4 | 3 | 23 | |
| GSE43470 | PRR12 | 57479 | 4 | 11 | 28 | |
| GSE46452 | PRR12 | 57479 | 45 | 1 | 13 | |
| GSE47630 | PRR12 | 57479 | 10 | 6 | 24 | |
| GSE54993 | PRR12 | 57479 | 17 | 4 | 49 | |
| GSE54994 | PRR12 | 57479 | 4 | 14 | 35 | |
| GSE60625 | PRR12 | 57479 | 9 | 0 | 2 | |
| GSE74703 | PRR12 | 57479 | 4 | 7 | 25 | |
| GSE74704 | PRR12 | 57479 | 4 | 1 | 15 | |
| TCGA | PRR12 | 57479 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of PRR12:
Generating mutation plots.
Highly correlated genes for PRR12:
Showing top 20/578 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR12 | MEA1 | 0.838118 | 3 | 0 | 3 |
| PRR12 | ZNF558 | 0.827853 | 3 | 0 | 3 |
| PRR12 | VAMP2 | 0.808573 | 3 | 0 | 3 |
| PRR12 | RSRC1 | 0.795394 | 3 | 0 | 3 |
| PRR12 | DROSHA | 0.792602 | 3 | 0 | 3 |
| PRR12 | TLN1 | 0.790129 | 3 | 0 | 3 |
| PRR12 | CCNT1 | 0.788291 | 3 | 0 | 3 |
| PRR12 | U2SURP | 0.787211 | 3 | 0 | 3 |
| PRR12 | PLXNA1 | 0.782407 | 3 | 0 | 3 |
| PRR12 | ZNF503 | 0.781925 | 3 | 0 | 3 |
| PRR12 | GRWD1 | 0.777654 | 3 | 0 | 3 |
| PRR12 | PRRC2A | 0.773572 | 3 | 0 | 3 |
| PRR12 | SRRT | 0.772075 | 4 | 0 | 3 |
| PRR12 | CTBP2 | 0.770548 | 3 | 0 | 3 |
| PRR12 | PA2G4 | 0.7686 | 3 | 0 | 3 |
| PRR12 | CSTF2T | 0.767892 | 3 | 0 | 3 |
| PRR12 | CPSF6 | 0.766529 | 3 | 0 | 3 |
| PRR12 | SZT2 | 0.76638 | 3 | 0 | 3 |
| PRR12 | SENP5 | 0.76605 | 3 | 0 | 3 |
| PRR12 | SETD1A | 0.765902 | 4 | 0 | 4 |
For details and further investigation, click here
