| Full name: transporter 1, ATP binding cassette subfamily B member | Alias Symbol: PSF1|RING4|D6S114E | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 6890 | HGNC ID: HGNC:43 | Ensembl Gene: ENSG00000168394 | OMIM ID: 170260 |
Expression of TAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAP1 | 6890 | 202307_s_at | 1.3800 | 0.1756 | |
| GSE20347 | TAP1 | 6890 | 202307_s_at | 0.7165 | 0.0123 | |
| GSE23400 | TAP1 | 6890 | 202307_s_at | 0.9134 | 0.0000 | |
| GSE26886 | TAP1 | 6890 | 202307_s_at | 1.0039 | 0.0127 | |
| GSE29001 | TAP1 | 6890 | 202307_s_at | 1.1396 | 0.0000 | |
| GSE38129 | TAP1 | 6890 | 202307_s_at | 0.7630 | 0.0003 | |
| GSE45670 | TAP1 | 6890 | 202307_s_at | 1.2318 | 0.0011 | |
| GSE63941 | TAP1 | 6890 | 202307_s_at | -0.8965 | 0.1285 | |
| GSE77861 | TAP1 | 6890 | 202307_s_at | 0.4270 | 0.0734 | |
| GSE97050 | TAP1 | 6890 | A_23_P59005 | 0.7179 | 0.2154 | |
| SRP007169 | TAP1 | 6890 | RNAseq | 0.9171 | 0.0476 | |
| SRP008496 | TAP1 | 6890 | RNAseq | 0.4381 | 0.1957 | |
| SRP064894 | TAP1 | 6890 | RNAseq | 1.0756 | 0.0000 | |
| SRP133303 | TAP1 | 6890 | RNAseq | 1.1876 | 0.0000 | |
| SRP159526 | TAP1 | 6890 | RNAseq | 0.1873 | 0.7395 | |
| SRP193095 | TAP1 | 6890 | RNAseq | 0.8054 | 0.0000 | |
| SRP219564 | TAP1 | 6890 | RNAseq | 1.8275 | 0.0043 | |
| TCGA | TAP1 | 6890 | RNAseq | 0.4317 | 0.0000 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by TAP1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAP1 | 6890 | 5 | 0 | 25 | |
| GSE20123 | TAP1 | 6890 | 5 | 0 | 25 | |
| GSE43470 | TAP1 | 6890 | 5 | 1 | 37 | |
| GSE46452 | TAP1 | 6890 | 2 | 10 | 47 | |
| GSE47630 | TAP1 | 6890 | 8 | 4 | 28 | |
| GSE54993 | TAP1 | 6890 | 3 | 1 | 66 | |
| GSE54994 | TAP1 | 6890 | 11 | 4 | 38 | |
| GSE60625 | TAP1 | 6890 | 1 | 0 | 10 | |
| GSE74703 | TAP1 | 6890 | 5 | 0 | 31 | |
| GSE74704 | TAP1 | 6890 | 2 | 0 | 18 | |
| TCGA | TAP1 | 6890 | 16 | 16 | 64 |
Total number of gains: 63; Total number of losses: 36; Total Number of normals: 389.
Somatic mutations of TAP1:
Generating mutation plots.
Highly correlated genes for TAP1:
Showing top 20/1044 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAP1 | TMEM237 | 0.823685 | 3 | 0 | 3 |
| TAP1 | PSMB9 | 0.807687 | 10 | 0 | 10 |
| TAP1 | GBP1 | 0.79444 | 11 | 0 | 11 |
| TAP1 | PSMB8 | 0.789398 | 10 | 0 | 10 |
| TAP1 | HLA-F | 0.78194 | 10 | 0 | 10 |
| TAP1 | CD80 | 0.775332 | 3 | 0 | 3 |
| TAP1 | UXS1 | 0.77178 | 4 | 0 | 4 |
| TAP1 | PARP14 | 0.765051 | 7 | 0 | 6 |
| TAP1 | STAT1 | 0.763766 | 11 | 0 | 11 |
| TAP1 | CXCL10 | 0.756553 | 11 | 0 | 10 |
| TAP1 | ALS2 | 0.754348 | 3 | 0 | 3 |
| TAP1 | RNF217 | 0.752639 | 3 | 0 | 3 |
| TAP1 | UBE2L6 | 0.747211 | 11 | 0 | 9 |
| TAP1 | PARP12 | 0.7463 | 11 | 0 | 9 |
| TAP1 | DDX60 | 0.745123 | 11 | 0 | 11 |
| TAP1 | RNF213 | 0.744901 | 5 | 0 | 4 |
| TAP1 | RBM39 | 0.744139 | 3 | 0 | 3 |
| TAP1 | TMEM63B | 0.743093 | 3 | 0 | 3 |
| TAP1 | HLA-A | 0.741941 | 11 | 0 | 10 |
| TAP1 | SLC39A10 | 0.741528 | 3 | 0 | 3 |
For details and further investigation, click here
