| Full name: ring finger protein 2 | Alias Symbol: BAP-1|BAP1|DING|HIPI3|RING1B|RING2 | ||
| Type: protein-coding gene | Cytoband: 1q25.3 | ||
| Entrez ID: 6045 | HGNC ID: HGNC:10061 | Ensembl Gene: ENSG00000121481 | OMIM ID: 608985 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF2 | 6045 | 205215_at | 0.5285 | 0.0701 | |
| GSE20347 | RNF2 | 6045 | 205215_at | 0.2333 | 0.0223 | |
| GSE23400 | RNF2 | 6045 | 205215_at | 0.2343 | 0.0000 | |
| GSE26886 | RNF2 | 6045 | 205215_at | 0.2582 | 0.0723 | |
| GSE29001 | RNF2 | 6045 | 205215_at | 0.5627 | 0.0190 | |
| GSE38129 | RNF2 | 6045 | 205215_at | 0.1843 | 0.0171 | |
| GSE45670 | RNF2 | 6045 | 205215_at | 0.3312 | 0.0001 | |
| GSE53622 | RNF2 | 6045 | 75816 | 0.7808 | 0.0000 | |
| GSE53624 | RNF2 | 6045 | 75816 | 0.8942 | 0.0000 | |
| GSE63941 | RNF2 | 6045 | 205215_at | -0.0244 | 0.9290 | |
| GSE77861 | RNF2 | 6045 | 205215_at | 0.1975 | 0.1374 | |
| GSE97050 | RNF2 | 6045 | A_23_P85543 | 0.5597 | 0.2113 | |
| SRP007169 | RNF2 | 6045 | RNAseq | 0.7250 | 0.0854 | |
| SRP008496 | RNF2 | 6045 | RNAseq | 1.0836 | 0.0000 | |
| SRP064894 | RNF2 | 6045 | RNAseq | 0.8342 | 0.0000 | |
| SRP133303 | RNF2 | 6045 | RNAseq | 0.9312 | 0.0000 | |
| SRP159526 | RNF2 | 6045 | RNAseq | 0.7453 | 0.0013 | |
| SRP193095 | RNF2 | 6045 | RNAseq | 0.5426 | 0.0000 | |
| SRP219564 | RNF2 | 6045 | RNAseq | 0.6159 | 0.1224 | |
| TCGA | RNF2 | 6045 | RNAseq | 0.2652 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RNF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF2 | 6045 | 12 | 0 | 18 | |
| GSE20123 | RNF2 | 6045 | 12 | 0 | 18 | |
| GSE43470 | RNF2 | 6045 | 7 | 1 | 35 | |
| GSE46452 | RNF2 | 6045 | 3 | 1 | 55 | |
| GSE47630 | RNF2 | 6045 | 14 | 0 | 26 | |
| GSE54993 | RNF2 | 6045 | 0 | 6 | 64 | |
| GSE54994 | RNF2 | 6045 | 15 | 0 | 38 | |
| GSE60625 | RNF2 | 6045 | 0 | 0 | 11 | |
| GSE74703 | RNF2 | 6045 | 7 | 1 | 28 | |
| GSE74704 | RNF2 | 6045 | 5 | 0 | 15 | |
| TCGA | RNF2 | 6045 | 40 | 3 | 53 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of RNF2:
Generating mutation plots.
Highly correlated genes for RNF2:
Showing top 20/1696 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF2 | DHODH | 0.780352 | 3 | 0 | 3 |
| RNF2 | FASN | 0.779942 | 3 | 0 | 3 |
| RNF2 | SNAP47 | 0.767513 | 3 | 0 | 3 |
| RNF2 | FADS1 | 0.767289 | 3 | 0 | 3 |
| RNF2 | PYCR2 | 0.765581 | 3 | 0 | 3 |
| RNF2 | FAM89A | 0.760803 | 3 | 0 | 3 |
| RNF2 | GNG10 | 0.760689 | 3 | 0 | 3 |
| RNF2 | NACC1 | 0.753582 | 3 | 0 | 3 |
| RNF2 | POLRMT | 0.752117 | 3 | 0 | 3 |
| RNF2 | MAD2L2 | 0.750729 | 4 | 0 | 4 |
| RNF2 | CEP170 | 0.741951 | 3 | 0 | 3 |
| RNF2 | FOXP4 | 0.731469 | 3 | 0 | 3 |
| RNF2 | RING1 | 0.729574 | 3 | 0 | 3 |
| RNF2 | SLC35B2 | 0.728047 | 3 | 0 | 3 |
| RNF2 | APOC1 | 0.727561 | 4 | 0 | 4 |
| RNF2 | SCNM1 | 0.726872 | 3 | 0 | 3 |
| RNF2 | ALG1 | 0.726512 | 3 | 0 | 3 |
| RNF2 | ZIC5 | 0.726322 | 3 | 0 | 3 |
| RNF2 | UNG | 0.723819 | 3 | 0 | 3 |
| RNF2 | ZNF121 | 0.720423 | 3 | 0 | 3 |
For details and further investigation, click here
