NMT1

 

Full name: N-myristoyltransferase 1 Alias Symbol: NMT
Type: protein-coding gene Cytoband: 17q21.31
Entrez ID: 4836 HGNC ID: HGNC:7857 Ensembl Gene: ENSG00000136448 OMIM ID: 160993
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NMT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NMT1 4836 201157_s_at 0.3128 0.2587
GSE20347 NMT1 4836 201157_s_at 0.3468 0.0047
GSE23400 NMT1 4836 201157_s_at 0.5664 0.0000
GSE26886 NMT1 4836 201157_s_at 0.8860 0.0000
GSE29001 NMT1 4836 201157_s_at 0.3887 0.1971
GSE38129 NMT1 4836 201157_s_at 0.5578 0.0000
GSE45670 NMT1 4836 201157_s_at 0.4472 0.0028
GSE53622 NMT1 4836 134125 0.3171 0.0000
GSE53624 NMT1 4836 134125 0.4394 0.0000
GSE63941 NMT1 4836 201157_s_at 0.5992 0.0799
GSE77861 NMT1 4836 201157_s_at 0.6737 0.0002
GSE97050 NMT1 4836 A_24_P14010 -0.2316 0.2709
SRP007169 NMT1 4836 RNAseq 0.9606 0.0086
SRP008496 NMT1 4836 RNAseq 0.7098 0.0042
SRP064894 NMT1 4836 RNAseq 0.5880 0.0000
SRP133303 NMT1 4836 RNAseq 0.3347 0.0387
SRP159526 NMT1 4836 RNAseq 0.0909 0.6560
SRP193095 NMT1 4836 RNAseq 0.3058 0.0009
SRP219564 NMT1 4836 RNAseq 0.3340 0.2395
TCGA NMT1 4836 RNAseq 0.0925 0.0287

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by NMT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NMT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NMT1 4836 6 2 22
GSE20123 NMT1 4836 6 2 22
GSE43470 NMT1 4836 1 2 40
GSE46452 NMT1 4836 32 0 27
GSE47630 NMT1 4836 9 0 31
GSE54993 NMT1 4836 3 4 63
GSE54994 NMT1 4836 9 5 39
GSE60625 NMT1 4836 4 0 7
GSE74703 NMT1 4836 1 1 34
GSE74704 NMT1 4836 4 1 15
TCGA NMT1 4836 27 6 63

Total number of gains: 102; Total number of losses: 23; Total Number of normals: 363.  

 

Somatic mutations of NMT1:

 

Generating mutation plots.

 

Highly correlated genes for NMT1:

 

Showing top 20/1744 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NMT1TMTC10.798416303
NMT1RAD23A0.773831505
NMT1NOL110.76584612011
NMT1RNF1390.76492303
NMT1PIBF10.764863303
NMT1BHLHB90.754994303
NMT1DAPK30.74824303
NMT1EFTUD20.747223808
NMT1COMMD20.73768404
NMT1PSMD120.73400912011
NMT1ALKBH60.732124504
NMT1FAM168B0.728313303
NMT1BLACAT10.727891404
NMT1MRPS310.726846303
NMT1KTI120.725779303
NMT1NIPA10.724581403
NMT1C15orf610.722743404
NMT1SLC39A30.722699303
NMT1C1orf1310.720511707
NMT1PTRH20.71868611010

For details and further investigation, click here