| Full name: ring finger protein 11 | Alias Symbol: CGI-123|Sid1669p|MGC51169 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 26994 | HGNC ID: HGNC:10056 | Ensembl Gene: ENSG00000123091 | OMIM ID: 612598 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RNF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF11 | 26994 | 208924_at | -0.4443 | 0.1094 | |
| GSE20347 | RNF11 | 26994 | 208924_at | -0.7790 | 0.0000 | |
| GSE23400 | RNF11 | 26994 | 208924_at | -0.7418 | 0.0000 | |
| GSE26886 | RNF11 | 26994 | 208924_at | -1.0505 | 0.0000 | |
| GSE29001 | RNF11 | 26994 | 208924_at | -0.7756 | 0.0670 | |
| GSE38129 | RNF11 | 26994 | 208924_at | -0.7618 | 0.0000 | |
| GSE45670 | RNF11 | 26994 | 208924_at | -0.3192 | 0.0654 | |
| GSE53622 | RNF11 | 26994 | 86204 | -0.9839 | 0.0000 | |
| GSE53624 | RNF11 | 26994 | 86204 | -1.0712 | 0.0000 | |
| GSE63941 | RNF11 | 26994 | 208924_at | -1.0220 | 0.0228 | |
| GSE77861 | RNF11 | 26994 | 208924_at | -1.0312 | 0.0038 | |
| GSE97050 | RNF11 | 26994 | A_23_P137434 | -0.5902 | 0.1450 | |
| SRP007169 | RNF11 | 26994 | RNAseq | -1.3705 | 0.0001 | |
| SRP008496 | RNF11 | 26994 | RNAseq | -1.2342 | 0.0000 | |
| SRP064894 | RNF11 | 26994 | RNAseq | -1.1203 | 0.0000 | |
| SRP133303 | RNF11 | 26994 | RNAseq | -0.5066 | 0.0077 | |
| SRP159526 | RNF11 | 26994 | RNAseq | -1.1039 | 0.0000 | |
| SRP193095 | RNF11 | 26994 | RNAseq | -1.2743 | 0.0000 | |
| SRP219564 | RNF11 | 26994 | RNAseq | -1.1675 | 0.0027 | |
| TCGA | RNF11 | 26994 | RNAseq | -0.1119 | 0.0139 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by RNF11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF11 | 26994 | 3 | 4 | 23 | |
| GSE20123 | RNF11 | 26994 | 3 | 3 | 24 | |
| GSE43470 | RNF11 | 26994 | 5 | 4 | 34 | |
| GSE46452 | RNF11 | 26994 | 2 | 1 | 56 | |
| GSE47630 | RNF11 | 26994 | 8 | 4 | 28 | |
| GSE54993 | RNF11 | 26994 | 0 | 1 | 69 | |
| GSE54994 | RNF11 | 26994 | 11 | 2 | 40 | |
| GSE60625 | RNF11 | 26994 | 0 | 0 | 11 | |
| GSE74703 | RNF11 | 26994 | 4 | 2 | 30 | |
| GSE74704 | RNF11 | 26994 | 2 | 0 | 18 | |
| TCGA | RNF11 | 26994 | 10 | 18 | 68 |
Total number of gains: 48; Total number of losses: 39; Total Number of normals: 401.
Somatic mutations of RNF11:
Generating mutation plots.
Highly correlated genes for RNF11:
Showing top 20/1576 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF11 | SCP2 | 0.807155 | 12 | 0 | 12 |
| RNF11 | CMPK1 | 0.806688 | 12 | 0 | 12 |
| RNF11 | FAM214A | 0.774793 | 6 | 0 | 6 |
| RNF11 | CYSRT1 | 0.773071 | 6 | 0 | 6 |
| RNF11 | SNORA68 | 0.76891 | 4 | 0 | 4 |
| RNF11 | KAT2B | 0.768297 | 12 | 0 | 12 |
| RNF11 | TMOD3 | 0.763254 | 11 | 0 | 11 |
| RNF11 | C12orf29 | 0.76301 | 11 | 0 | 11 |
| RNF11 | C18orf25 | 0.761811 | 11 | 0 | 11 |
| RNF11 | CAST | 0.760907 | 11 | 0 | 11 |
| RNF11 | CAPN14 | 0.758786 | 6 | 0 | 6 |
| RNF11 | CPPED1 | 0.756817 | 11 | 0 | 11 |
| RNF11 | IL34 | 0.753612 | 3 | 0 | 3 |
| RNF11 | SORT1 | 0.752675 | 11 | 0 | 11 |
| RNF11 | S100A16 | 0.751761 | 6 | 0 | 6 |
| RNF11 | KDM3A | 0.75111 | 4 | 0 | 4 |
| RNF11 | FCHO2 | 0.749031 | 8 | 0 | 7 |
| RNF11 | CYP2J2 | 0.747991 | 10 | 0 | 10 |
| RNF11 | RNF141 | 0.747808 | 12 | 0 | 11 |
| RNF11 | CCNYL1 | 0.747545 | 5 | 0 | 5 |
For details and further investigation, click here
