RNF141

 

Full name: ring finger protein 141 Alias Symbol: ZFP26|ZNF230
Type: protein-coding gene Cytoband: 11p15.3
Entrez ID: 50862 HGNC ID: HGNC:21159 Ensembl Gene: ENSG00000110315 OMIM ID: 616641
Drug and gene relationship at DGIdb

 

Expression of RNF141:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNF141 50862 226106_at -1.2183 0.1045
GSE20347 RNF141 50862 219104_at -1.8681 0.0000
GSE23400 RNF141 50862 219104_at -1.2351 0.0000
GSE26886 RNF141 50862 226106_at -1.3355 0.0001
GSE29001 RNF141 50862 219104_at -2.1062 0.0000
GSE38129 RNF141 50862 219104_at -1.3004 0.0000
GSE45670 RNF141 50862 226106_at -0.6262 0.0234
GSE53622 RNF141 50862 109473 -1.6700 0.0000
GSE53624 RNF141 50862 109473 -1.9119 0.0000
GSE63941 RNF141 50862 226106_at -0.9206 0.0144
GSE77861 RNF141 50862 226106_at -1.6298 0.0013
GSE97050 RNF141 50862 A_24_P372625 -1.2446 0.0863
SRP007169 RNF141 50862 RNAseq -3.0674 0.0000
SRP008496 RNF141 50862 RNAseq -2.8770 0.0000
SRP064894 RNF141 50862 RNAseq -2.2554 0.0000
SRP133303 RNF141 50862 RNAseq -1.0286 0.0000
SRP159526 RNF141 50862 RNAseq -1.8966 0.0000
SRP193095 RNF141 50862 RNAseq -1.8249 0.0000
SRP219564 RNF141 50862 RNAseq -1.7136 0.0031
TCGA RNF141 50862 RNAseq -0.0876 0.2288

Upregulated datasets: 0; Downregulated datasets: 15.  

 

Survival by RNF141 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RNF141:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNF141 50862 0 9 21
GSE20123 RNF141 50862 0 10 20
GSE43470 RNF141 50862 1 6 36
GSE46452 RNF141 50862 7 5 47
GSE47630 RNF141 50862 3 11 26
GSE54993 RNF141 50862 3 1 66
GSE54994 RNF141 50862 3 12 38
GSE60625 RNF141 50862 0 0 11
GSE74703 RNF141 50862 1 4 31
GSE74704 RNF141 50862 0 7 13
TCGA RNF141 50862 11 34 51

Total number of gains: 29; Total number of losses: 99; Total Number of normals: 360.  

 

Somatic mutations of RNF141:

 

Generating mutation plots.

 

Highly correlated genes for RNF141:

 

Showing top 20/1859 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNF141CA130.858821303
RNF141FCHO20.851671707
RNF141C18orf250.84870911011
RNF141RAB11A0.84425812011
RNF141ACPP0.83990610010
RNF141ECM10.83906810010
RNF141SCNN1B0.83903210010
RNF141CHP10.83778910010
RNF141GDPD30.83711810010
RNF141ACOX30.8365110010
RNF141CLCA40.83590610010
RNF141CCNG20.83312511011
RNF141MXD10.83084310010
RNF141WDR260.82997610010
RNF141SLURP10.82886310010
RNF141MAL0.82857510010
RNF141TAB30.827367707
RNF141KAT2B0.82688511011
RNF141TOLLIP0.82491310010
RNF141SPINK50.82363310010

For details and further investigation, click here