| Full name: lysine demethylase 3A | Alias Symbol: TSGA|KIAA0742|JHMD2A | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 55818 | HGNC ID: HGNC:20815 | Ensembl Gene: ENSG00000115548 | OMIM ID: 611512 |
| Drug and gene relationship at DGIdb | |||
Expression of KDM3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KDM3A | 55818 | 212689_s_at | -0.6285 | 0.1225 | |
| GSE20347 | KDM3A | 55818 | 212689_s_at | 0.1434 | 0.5125 | |
| GSE23400 | KDM3A | 55818 | 212689_s_at | 0.2722 | 0.0059 | |
| GSE26886 | KDM3A | 55818 | 212689_s_at | -0.3832 | 0.1376 | |
| GSE29001 | KDM3A | 55818 | 212689_s_at | -0.3749 | 0.3531 | |
| GSE38129 | KDM3A | 55818 | 212689_s_at | 0.2734 | 0.0952 | |
| GSE45670 | KDM3A | 55818 | 212689_s_at | 0.0295 | 0.9015 | |
| GSE63941 | KDM3A | 55818 | 212689_s_at | 0.2794 | 0.5677 | |
| GSE77861 | KDM3A | 55818 | 212689_s_at | 0.5560 | 0.0783 | |
| GSE97050 | KDM3A | 55818 | A_23_P395075 | -0.1530 | 0.4989 | |
| SRP007169 | KDM3A | 55818 | RNAseq | -0.1255 | 0.7886 | |
| SRP008496 | KDM3A | 55818 | RNAseq | -0.1455 | 0.6302 | |
| SRP064894 | KDM3A | 55818 | RNAseq | -0.3350 | 0.2473 | |
| SRP133303 | KDM3A | 55818 | RNAseq | -0.0384 | 0.7869 | |
| SRP159526 | KDM3A | 55818 | RNAseq | -0.2344 | 0.3375 | |
| SRP193095 | KDM3A | 55818 | RNAseq | -0.1714 | 0.2714 | |
| SRP219564 | KDM3A | 55818 | RNAseq | -0.5901 | 0.1498 | |
| TCGA | KDM3A | 55818 | RNAseq | 0.1173 | 0.0218 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KDM3A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KDM3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KDM3A | 55818 | 9 | 2 | 19 | |
| GSE20123 | KDM3A | 55818 | 9 | 2 | 19 | |
| GSE43470 | KDM3A | 55818 | 3 | 2 | 38 | |
| GSE46452 | KDM3A | 55818 | 2 | 3 | 54 | |
| GSE47630 | KDM3A | 55818 | 7 | 0 | 33 | |
| GSE54993 | KDM3A | 55818 | 0 | 6 | 64 | |
| GSE54994 | KDM3A | 55818 | 10 | 0 | 43 | |
| GSE60625 | KDM3A | 55818 | 0 | 3 | 8 | |
| GSE74703 | KDM3A | 55818 | 3 | 1 | 32 | |
| GSE74704 | KDM3A | 55818 | 7 | 0 | 13 | |
| TCGA | KDM3A | 55818 | 35 | 4 | 57 |
Total number of gains: 85; Total number of losses: 23; Total Number of normals: 380.
Somatic mutations of KDM3A:
Generating mutation plots.
Highly correlated genes for KDM3A:
Showing top 20/287 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KDM3A | AK3 | 0.800916 | 3 | 0 | 3 |
| KDM3A | ZRANB1 | 0.788915 | 3 | 0 | 3 |
| KDM3A | PRKAB1 | 0.782808 | 3 | 0 | 3 |
| KDM3A | SOS2 | 0.769049 | 3 | 0 | 3 |
| KDM3A | PPM1A | 0.767186 | 3 | 0 | 3 |
| KDM3A | LANCL1 | 0.767077 | 3 | 0 | 3 |
| KDM3A | NCKAP1 | 0.765533 | 3 | 0 | 3 |
| KDM3A | SEC24B | 0.763175 | 4 | 0 | 4 |
| KDM3A | FBXO8 | 0.76026 | 3 | 0 | 3 |
| KDM3A | SLC35A3 | 0.759815 | 3 | 0 | 3 |
| KDM3A | WDR26 | 0.755569 | 3 | 0 | 3 |
| KDM3A | RNF11 | 0.75111 | 4 | 0 | 4 |
| KDM3A | APPBP2 | 0.747817 | 3 | 0 | 3 |
| KDM3A | MDFIC | 0.746624 | 3 | 0 | 3 |
| KDM3A | IRAK4 | 0.742025 | 4 | 0 | 4 |
| KDM3A | FBXL3 | 0.740166 | 3 | 0 | 3 |
| KDM3A | CCNDBP1 | 0.738656 | 3 | 0 | 3 |
| KDM3A | THAP2 | 0.737575 | 3 | 0 | 3 |
| KDM3A | RSBN1 | 0.735456 | 3 | 0 | 3 |
| KDM3A | EZR | 0.734562 | 3 | 0 | 3 |
For details and further investigation, click here
