| Full name: chromosome 18 open reading frame 25 | Alias Symbol: MGC12909|ARKL1|RNF111L1|Ark2N | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 147339 | HGNC ID: HGNC:28172 | Ensembl Gene: ENSG00000152242 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C18orf25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C18orf25 | 147339 | 226406_at | -0.7656 | 0.1027 | |
| GSE20347 | C18orf25 | 147339 | 217508_s_at | -2.1810 | 0.0000 | |
| GSE23400 | C18orf25 | 147339 | 217508_s_at | -1.3497 | 0.0000 | |
| GSE26886 | C18orf25 | 147339 | 226406_at | -2.7177 | 0.0000 | |
| GSE29001 | C18orf25 | 147339 | 217508_s_at | -2.5585 | 0.0000 | |
| GSE38129 | C18orf25 | 147339 | 217508_s_at | -1.7169 | 0.0000 | |
| GSE45670 | C18orf25 | 147339 | 226406_at | -0.8890 | 0.0013 | |
| GSE53622 | C18orf25 | 147339 | 5172 | -1.4526 | 0.0000 | |
| GSE53624 | C18orf25 | 147339 | 5172 | -1.8233 | 0.0000 | |
| GSE63941 | C18orf25 | 147339 | 226406_at | -0.3623 | 0.3992 | |
| GSE77861 | C18orf25 | 147339 | 226406_at | -1.1950 | 0.0129 | |
| GSE97050 | C18orf25 | 147339 | A_23_P345361 | -0.5879 | 0.1787 | |
| SRP007169 | C18orf25 | 147339 | RNAseq | -3.7029 | 0.0000 | |
| SRP008496 | C18orf25 | 147339 | RNAseq | -2.8687 | 0.0000 | |
| SRP064894 | C18orf25 | 147339 | RNAseq | -2.8486 | 0.0000 | |
| SRP133303 | C18orf25 | 147339 | RNAseq | -1.6606 | 0.0000 | |
| SRP159526 | C18orf25 | 147339 | RNAseq | -1.8049 | 0.0000 | |
| SRP193095 | C18orf25 | 147339 | RNAseq | -2.3506 | 0.0000 | |
| SRP219564 | C18orf25 | 147339 | RNAseq | -2.1283 | 0.0012 | |
| TCGA | C18orf25 | 147339 | RNAseq | -0.0329 | 0.6150 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by C18orf25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C18orf25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C18orf25 | 147339 | 1 | 8 | 21 | |
| GSE20123 | C18orf25 | 147339 | 1 | 8 | 21 | |
| GSE43470 | C18orf25 | 147339 | 0 | 4 | 39 | |
| GSE46452 | C18orf25 | 147339 | 1 | 26 | 32 | |
| GSE47630 | C18orf25 | 147339 | 5 | 20 | 15 | |
| GSE54993 | C18orf25 | 147339 | 8 | 1 | 61 | |
| GSE54994 | C18orf25 | 147339 | 2 | 15 | 36 | |
| GSE60625 | C18orf25 | 147339 | 0 | 4 | 7 | |
| GSE74703 | C18orf25 | 147339 | 0 | 3 | 33 | |
| GSE74704 | C18orf25 | 147339 | 0 | 6 | 14 | |
| TCGA | C18orf25 | 147339 | 14 | 40 | 42 |
Total number of gains: 32; Total number of losses: 135; Total Number of normals: 321.
Somatic mutations of C18orf25:
Generating mutation plots.
Highly correlated genes for C18orf25:
Showing top 20/1785 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C18orf25 | GYS2 | 0.887335 | 10 | 0 | 10 |
| C18orf25 | IL36A | 0.873439 | 10 | 0 | 10 |
| C18orf25 | FAM214A | 0.870191 | 6 | 0 | 6 |
| C18orf25 | SASH1 | 0.86841 | 11 | 0 | 11 |
| C18orf25 | MXD1 | 0.866601 | 10 | 0 | 10 |
| C18orf25 | TAB3 | 0.865058 | 7 | 0 | 7 |
| C18orf25 | ECM1 | 0.861152 | 10 | 0 | 10 |
| C18orf25 | YOD1 | 0.860509 | 11 | 0 | 11 |
| C18orf25 | SPINK7 | 0.860237 | 6 | 0 | 6 |
| C18orf25 | CYSRT1 | 0.859917 | 6 | 0 | 6 |
| C18orf25 | C5orf66-AS1 | 0.859604 | 6 | 0 | 6 |
| C18orf25 | RMND5B | 0.859483 | 11 | 0 | 11 |
| C18orf25 | SNORA68 | 0.859282 | 4 | 0 | 4 |
| C18orf25 | SCEL | 0.859026 | 10 | 0 | 10 |
| C18orf25 | SH3BGRL2 | 0.85649 | 7 | 0 | 7 |
| C18orf25 | SCNN1B | 0.855555 | 10 | 0 | 10 |
| C18orf25 | TTC9 | 0.854383 | 11 | 0 | 11 |
| C18orf25 | DUSP5 | 0.854223 | 11 | 0 | 11 |
| C18orf25 | RAB11A | 0.853425 | 11 | 0 | 11 |
| C18orf25 | PRSS27 | 0.852947 | 6 | 0 | 6 |
For details and further investigation, click here
