| Full name: cytidine/uridine monophosphate kinase 1 | Alias Symbol: UMP-CMPK | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 51727 | HGNC ID: HGNC:18170 | Ensembl Gene: ENSG00000162368 | OMIM ID: 191710 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CMPK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CMPK1 | 51727 | 217870_s_at | -0.5499 | 0.0868 | |
| GSE20347 | CMPK1 | 51727 | 217870_s_at | -0.9594 | 0.0000 | |
| GSE23400 | CMPK1 | 51727 | 217870_s_at | -0.6464 | 0.0000 | |
| GSE26886 | CMPK1 | 51727 | 217870_s_at | -1.4435 | 0.0000 | |
| GSE29001 | CMPK1 | 51727 | 217870_s_at | -0.7537 | 0.0037 | |
| GSE38129 | CMPK1 | 51727 | 217870_s_at | -0.7827 | 0.0000 | |
| GSE45670 | CMPK1 | 51727 | 217870_s_at | -0.2720 | 0.1445 | |
| GSE53622 | CMPK1 | 51727 | 13487 | -1.1307 | 0.0000 | |
| GSE53624 | CMPK1 | 51727 | 13487 | -0.8681 | 0.0000 | |
| GSE63941 | CMPK1 | 51727 | 222448_s_at | -0.2990 | 0.5190 | |
| GSE77861 | CMPK1 | 51727 | 217870_s_at | -1.1340 | 0.0031 | |
| GSE97050 | CMPK1 | 51727 | A_33_P3317988 | 0.0783 | 0.7102 | |
| SRP007169 | CMPK1 | 51727 | RNAseq | -2.1132 | 0.0000 | |
| SRP008496 | CMPK1 | 51727 | RNAseq | -1.9967 | 0.0000 | |
| SRP064894 | CMPK1 | 51727 | RNAseq | -0.7316 | 0.0000 | |
| SRP133303 | CMPK1 | 51727 | RNAseq | -0.4546 | 0.0113 | |
| SRP159526 | CMPK1 | 51727 | RNAseq | -1.0911 | 0.0000 | |
| SRP193095 | CMPK1 | 51727 | RNAseq | -1.0073 | 0.0000 | |
| SRP219564 | CMPK1 | 51727 | RNAseq | -0.2380 | 0.5746 | |
| TCGA | CMPK1 | 51727 | RNAseq | -0.1373 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by CMPK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CMPK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CMPK1 | 51727 | 4 | 3 | 23 | |
| GSE20123 | CMPK1 | 51727 | 4 | 2 | 24 | |
| GSE43470 | CMPK1 | 51727 | 5 | 1 | 37 | |
| GSE46452 | CMPK1 | 51727 | 2 | 1 | 56 | |
| GSE47630 | CMPK1 | 51727 | 8 | 4 | 28 | |
| GSE54993 | CMPK1 | 51727 | 0 | 1 | 69 | |
| GSE54994 | CMPK1 | 51727 | 11 | 2 | 40 | |
| GSE60625 | CMPK1 | 51727 | 0 | 0 | 11 | |
| GSE74703 | CMPK1 | 51727 | 4 | 1 | 31 | |
| GSE74704 | CMPK1 | 51727 | 2 | 0 | 18 | |
| TCGA | CMPK1 | 51727 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of CMPK1:
Generating mutation plots.
Highly correlated genes for CMPK1:
Showing top 20/1781 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CMPK1 | RNF11 | 0.806688 | 12 | 0 | 12 |
| CMPK1 | PLEKHA7 | 0.805896 | 7 | 0 | 7 |
| CMPK1 | SCP2 | 0.788828 | 13 | 0 | 11 |
| CMPK1 | UBL3 | 0.784898 | 10 | 0 | 10 |
| CMPK1 | RNF141 | 0.775902 | 11 | 0 | 11 |
| CMPK1 | BRK1 | 0.768546 | 7 | 0 | 7 |
| CMPK1 | KRT78 | 0.768101 | 6 | 0 | 6 |
| CMPK1 | DUSP22 | 0.764617 | 10 | 0 | 10 |
| CMPK1 | CYP2J2 | 0.762684 | 10 | 0 | 10 |
| CMPK1 | C5orf66-AS1 | 0.762111 | 6 | 0 | 6 |
| CMPK1 | FAM71C | 0.761383 | 3 | 0 | 3 |
| CMPK1 | CAPN14 | 0.760404 | 6 | 0 | 6 |
| CMPK1 | RMND5B | 0.759538 | 11 | 0 | 11 |
| CMPK1 | FAM214A | 0.758826 | 6 | 0 | 6 |
| CMPK1 | CCDC6 | 0.757379 | 11 | 0 | 11 |
| CMPK1 | SERPINB1 | 0.757027 | 10 | 0 | 10 |
| CMPK1 | SERPINB6 | 0.757003 | 10 | 0 | 10 |
| CMPK1 | RAB11A | 0.753299 | 11 | 0 | 11 |
| CMPK1 | SLC44A3 | 0.753151 | 7 | 0 | 7 |
| CMPK1 | CPPED1 | 0.75218 | 11 | 0 | 11 |
For details and further investigation, click here
