| Full name: tropomodulin 3 | Alias Symbol: UTMOD | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 29766 | HGNC ID: HGNC:11873 | Ensembl Gene: ENSG00000138594 | OMIM ID: 605112 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TMOD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMOD3 | 29766 | 223077_at | -1.0113 | 0.2391 | |
| GSE20347 | TMOD3 | 29766 | 220800_s_at | -2.5500 | 0.0000 | |
| GSE23400 | TMOD3 | 29766 | 220800_s_at | -1.6994 | 0.0000 | |
| GSE26886 | TMOD3 | 29766 | 223077_at | -1.7405 | 0.0000 | |
| GSE29001 | TMOD3 | 29766 | 220800_s_at | -2.1970 | 0.0001 | |
| GSE38129 | TMOD3 | 29766 | 220800_s_at | -1.7236 | 0.0000 | |
| GSE45670 | TMOD3 | 29766 | 223077_at | -0.7752 | 0.0042 | |
| GSE53622 | TMOD3 | 29766 | 82635 | -1.5899 | 0.0000 | |
| GSE53624 | TMOD3 | 29766 | 52952 | -1.8103 | 0.0000 | |
| GSE63941 | TMOD3 | 29766 | 223077_at | 0.1744 | 0.6767 | |
| GSE77861 | TMOD3 | 29766 | 223077_at | -1.4945 | 0.0027 | |
| GSE97050 | TMOD3 | 29766 | A_23_P65674 | -0.8400 | 0.4168 | |
| SRP007169 | TMOD3 | 29766 | RNAseq | -2.7623 | 0.0000 | |
| SRP008496 | TMOD3 | 29766 | RNAseq | -2.5879 | 0.0000 | |
| SRP064894 | TMOD3 | 29766 | RNAseq | -2.3237 | 0.0000 | |
| SRP133303 | TMOD3 | 29766 | RNAseq | -1.2503 | 0.0000 | |
| SRP159526 | TMOD3 | 29766 | RNAseq | -2.0755 | 0.0000 | |
| SRP193095 | TMOD3 | 29766 | RNAseq | -1.8470 | 0.0000 | |
| SRP219564 | TMOD3 | 29766 | RNAseq | -1.8995 | 0.0067 | |
| TCGA | TMOD3 | 29766 | RNAseq | 0.0439 | 0.4513 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by TMOD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMOD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMOD3 | 29766 | 6 | 4 | 20 | |
| GSE20123 | TMOD3 | 29766 | 6 | 4 | 20 | |
| GSE43470 | TMOD3 | 29766 | 4 | 3 | 36 | |
| GSE46452 | TMOD3 | 29766 | 3 | 7 | 49 | |
| GSE47630 | TMOD3 | 29766 | 8 | 10 | 22 | |
| GSE54993 | TMOD3 | 29766 | 5 | 6 | 59 | |
| GSE54994 | TMOD3 | 29766 | 5 | 7 | 41 | |
| GSE60625 | TMOD3 | 29766 | 4 | 0 | 7 | |
| GSE74703 | TMOD3 | 29766 | 4 | 2 | 30 | |
| GSE74704 | TMOD3 | 29766 | 2 | 3 | 15 | |
| TCGA | TMOD3 | 29766 | 9 | 17 | 70 |
Total number of gains: 56; Total number of losses: 63; Total Number of normals: 369.
Somatic mutations of TMOD3:
Generating mutation plots.
Highly correlated genes for TMOD3:
Showing top 20/1854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMOD3 | CAPN14 | 0.882085 | 6 | 0 | 6 |
| TMOD3 | KRT78 | 0.878896 | 7 | 0 | 7 |
| TMOD3 | ECM1 | 0.876381 | 11 | 0 | 11 |
| TMOD3 | CHP1 | 0.868618 | 10 | 0 | 10 |
| TMOD3 | RANBP9 | 0.867267 | 11 | 0 | 11 |
| TMOD3 | GYS2 | 0.865456 | 10 | 0 | 10 |
| TMOD3 | CWH43 | 0.861702 | 10 | 0 | 10 |
| TMOD3 | TP53I3 | 0.860526 | 11 | 0 | 11 |
| TMOD3 | IL18 | 0.857566 | 11 | 0 | 11 |
| TMOD3 | EVPL | 0.855787 | 11 | 0 | 11 |
| TMOD3 | ENDOU | 0.854208 | 11 | 0 | 11 |
| TMOD3 | EHD3 | 0.849573 | 11 | 0 | 11 |
| TMOD3 | C18orf25 | 0.848791 | 11 | 0 | 11 |
| TMOD3 | ARHGAP27 | 0.847404 | 7 | 0 | 7 |
| TMOD3 | RAB10 | 0.846028 | 7 | 0 | 7 |
| TMOD3 | CXCR2 | 0.844107 | 10 | 0 | 10 |
| TMOD3 | C15orf48 | 0.843661 | 7 | 0 | 7 |
| TMOD3 | CYSRT1 | 0.841457 | 7 | 0 | 6 |
| TMOD3 | TMPRSS11B | 0.841105 | 7 | 0 | 7 |
| TMOD3 | BNIPL | 0.84034 | 7 | 0 | 7 |
For details and further investigation, click here
