| Full name: ring finger protein 138 | Alias Symbol: STRIN|NARF | ||
| Type: protein-coding gene | Cytoband: 18q12.1 | ||
| Entrez ID: 51444 | HGNC ID: HGNC:17765 | Ensembl Gene: ENSG00000134758 | OMIM ID: 616319 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF138:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF138 | 51444 | 218738_s_at | 0.3394 | 0.6881 | |
| GSE20347 | RNF138 | 51444 | 218738_s_at | 0.3578 | 0.0506 | |
| GSE23400 | RNF138 | 51444 | 218738_s_at | 0.6087 | 0.0000 | |
| GSE26886 | RNF138 | 51444 | 218738_s_at | -0.0234 | 0.9441 | |
| GSE29001 | RNF138 | 51444 | 218738_s_at | 0.4785 | 0.2615 | |
| GSE38129 | RNF138 | 51444 | 218738_s_at | 0.3112 | 0.0429 | |
| GSE45670 | RNF138 | 51444 | 218738_s_at | 0.1362 | 0.6061 | |
| GSE53622 | RNF138 | 51444 | 84828 | -0.1867 | 0.0118 | |
| GSE53624 | RNF138 | 51444 | 84828 | 0.1011 | 0.2157 | |
| GSE63941 | RNF138 | 51444 | 218738_s_at | 1.3436 | 0.0096 | |
| GSE77861 | RNF138 | 51444 | 218738_s_at | 0.4825 | 0.2564 | |
| GSE97050 | RNF138 | 51444 | A_23_P89755 | 0.0207 | 0.9281 | |
| SRP007169 | RNF138 | 51444 | RNAseq | 0.5234 | 0.3359 | |
| SRP008496 | RNF138 | 51444 | RNAseq | 0.5183 | 0.1178 | |
| SRP064894 | RNF138 | 51444 | RNAseq | -0.3313 | 0.0879 | |
| SRP133303 | RNF138 | 51444 | RNAseq | 0.2364 | 0.3767 | |
| SRP159526 | RNF138 | 51444 | RNAseq | 0.0056 | 0.9826 | |
| SRP193095 | RNF138 | 51444 | RNAseq | -0.2667 | 0.0223 | |
| SRP219564 | RNF138 | 51444 | RNAseq | -0.1793 | 0.4468 | |
| TCGA | RNF138 | 51444 | RNAseq | 0.0511 | 0.3667 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RNF138 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF138:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF138 | 51444 | 1 | 6 | 23 | |
| GSE20123 | RNF138 | 51444 | 1 | 6 | 23 | |
| GSE43470 | RNF138 | 51444 | 0 | 3 | 40 | |
| GSE46452 | RNF138 | 51444 | 1 | 25 | 33 | |
| GSE47630 | RNF138 | 51444 | 5 | 20 | 15 | |
| GSE54993 | RNF138 | 51444 | 8 | 1 | 61 | |
| GSE54994 | RNF138 | 51444 | 1 | 16 | 36 | |
| GSE60625 | RNF138 | 51444 | 0 | 4 | 7 | |
| GSE74703 | RNF138 | 51444 | 0 | 3 | 33 | |
| GSE74704 | RNF138 | 51444 | 0 | 5 | 15 | |
| TCGA | RNF138 | 51444 | 14 | 35 | 47 |
Total number of gains: 31; Total number of losses: 124; Total Number of normals: 333.
Somatic mutations of RNF138:
Generating mutation plots.
Highly correlated genes for RNF138:
Showing top 20/755 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF138 | MCPH1 | 0.830483 | 3 | 0 | 3 |
| RNF138 | TMEM205 | 0.816159 | 3 | 0 | 3 |
| RNF138 | PIK3R3 | 0.809753 | 3 | 0 | 3 |
| RNF138 | ERGIC2 | 0.801156 | 3 | 0 | 3 |
| RNF138 | ZNRD1 | 0.782491 | 3 | 0 | 3 |
| RNF138 | MRPL38 | 0.778855 | 3 | 0 | 3 |
| RNF138 | L3MBTL3 | 0.776052 | 3 | 0 | 3 |
| RNF138 | RBM4B | 0.771086 | 3 | 0 | 3 |
| RNF138 | SENP1 | 0.765826 | 3 | 0 | 3 |
| RNF138 | LEMD2 | 0.765499 | 3 | 0 | 3 |
| RNF138 | WDR70 | 0.760951 | 3 | 0 | 3 |
| RNF138 | ZBTB2 | 0.754907 | 3 | 0 | 3 |
| RNF138 | INO80E | 0.747537 | 3 | 0 | 3 |
| RNF138 | KLF11 | 0.744495 | 3 | 0 | 3 |
| RNF138 | SLC25A19 | 0.738359 | 3 | 0 | 3 |
| RNF138 | ERCC8 | 0.738298 | 3 | 0 | 3 |
| RNF138 | REPS1 | 0.733548 | 3 | 0 | 3 |
| RNF138 | DMXL2 | 0.730372 | 3 | 0 | 3 |
| RNF138 | ZBED1 | 0.729267 | 3 | 0 | 3 |
| RNF138 | MMRN2 | 0.725746 | 3 | 0 | 3 |
For details and further investigation, click here
