| Full name: ring finger protein 214 | Alias Symbol: DKFZp547C195 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 257160 | HGNC ID: HGNC:25335 | Ensembl Gene: ENSG00000167257 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RNF214:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF214 | 257160 | 227114_at | -0.1119 | 0.7108 | |
| GSE26886 | RNF214 | 257160 | 227114_at | -0.1917 | 0.3169 | |
| GSE45670 | RNF214 | 257160 | 227114_at | 0.1162 | 0.2348 | |
| GSE63941 | RNF214 | 257160 | 227114_at | -0.5270 | 0.1163 | |
| GSE77861 | RNF214 | 257160 | 227114_at | -0.0077 | 0.9546 | |
| GSE97050 | RNF214 | 257160 | A_24_P32520 | -0.8079 | 0.0835 | |
| SRP007169 | RNF214 | 257160 | RNAseq | 1.0220 | 0.0822 | |
| SRP008496 | RNF214 | 257160 | RNAseq | 0.9208 | 0.0479 | |
| SRP064894 | RNF214 | 257160 | RNAseq | 0.2012 | 0.0827 | |
| SRP133303 | RNF214 | 257160 | RNAseq | -0.5595 | 0.0000 | |
| SRP159526 | RNF214 | 257160 | RNAseq | -0.0754 | 0.8243 | |
| SRP193095 | RNF214 | 257160 | RNAseq | -0.2571 | 0.0610 | |
| SRP219564 | RNF214 | 257160 | RNAseq | -0.2641 | 0.3582 | |
| TCGA | RNF214 | 257160 | RNAseq | -0.1758 | 0.0020 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF214 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RNF214:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF214 | 257160 | 1 | 13 | 16 | |
| GSE20123 | RNF214 | 257160 | 1 | 13 | 16 | |
| GSE43470 | RNF214 | 257160 | 2 | 8 | 33 | |
| GSE46452 | RNF214 | 257160 | 3 | 26 | 30 | |
| GSE47630 | RNF214 | 257160 | 2 | 19 | 19 | |
| GSE54993 | RNF214 | 257160 | 10 | 0 | 60 | |
| GSE54994 | RNF214 | 257160 | 5 | 19 | 29 | |
| GSE60625 | RNF214 | 257160 | 0 | 3 | 8 | |
| GSE74703 | RNF214 | 257160 | 1 | 5 | 30 | |
| GSE74704 | RNF214 | 257160 | 0 | 9 | 11 | |
| TCGA | RNF214 | 257160 | 5 | 50 | 41 |
Total number of gains: 30; Total number of losses: 165; Total Number of normals: 293.
Somatic mutations of RNF214:
Generating mutation plots.
Highly correlated genes for RNF214:
Showing top 20/114 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF214 | C11orf68 | 0.799223 | 3 | 0 | 3 |
| RNF214 | LDOC1 | 0.797129 | 3 | 0 | 3 |
| RNF214 | WEE1 | 0.778893 | 3 | 0 | 3 |
| RNF214 | DMD | 0.762679 | 3 | 0 | 3 |
| RNF214 | F8 | 0.754177 | 3 | 0 | 3 |
| RNF214 | ILK | 0.749811 | 3 | 0 | 3 |
| RNF214 | MAPK12 | 0.744024 | 3 | 0 | 3 |
| RNF214 | DNAJB4 | 0.743209 | 4 | 0 | 3 |
| RNF214 | MAP1LC3A | 0.741516 | 3 | 0 | 3 |
| RNF214 | EDA2R | 0.739669 | 3 | 0 | 3 |
| RNF214 | PLCD3 | 0.739451 | 3 | 0 | 3 |
| RNF214 | KAT7 | 0.738077 | 3 | 0 | 3 |
| RNF214 | MAP1A | 0.735485 | 3 | 0 | 3 |
| RNF214 | ZNF747 | 0.733998 | 3 | 0 | 3 |
| RNF214 | GSX1 | 0.730258 | 3 | 0 | 3 |
| RNF214 | RBL2 | 0.724675 | 3 | 0 | 3 |
| RNF214 | FOXF1 | 0.724009 | 3 | 0 | 3 |
| RNF214 | PTPRD | 0.722646 | 3 | 0 | 3 |
| RNF214 | C20orf96 | 0.719987 | 3 | 0 | 3 |
| RNF214 | TRIP6 | 0.718266 | 3 | 0 | 3 |
For details and further investigation, click here
