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Severity: Warning

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Filename: controllers/Result_pages.php

Line Number: 97

Backtrace:

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 97
Function: exec

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 399
Function: drawMutations

File: /data/webapp/var/www/html/ESCCdb/index.php
Line: 315
Function: require_once

Multi-Omics Database of ESCC

 

DNAJB4

 

Full name: DnaJ heat shock protein family (Hsp40) member B4 Alias Symbol: HLJ1
Type: protein-coding gene Cytoband: 1p31.1
Entrez ID: 11080 HGNC ID: HGNC:14886 Ensembl Gene: ENSG00000162616 OMIM ID: 611327
Drug and gene relationship at DGIdb

 

Expression of DNAJB4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DNAJB4 11080 203810_at -0.7870 0.3688
GSE20347 DNAJB4 11080 203810_at -0.1356 0.7030
GSE23400 DNAJB4 11080 203810_at 0.0353 0.8088
GSE26886 DNAJB4 11080 203810_at -0.9287 0.0007
GSE29001 DNAJB4 11080 203810_at -0.1954 0.7599
GSE38129 DNAJB4 11080 203810_at -0.3366 0.1701
GSE45670 DNAJB4 11080 203810_at -0.1483 0.6876
GSE53622 DNAJB4 11080 150012 -0.3457 0.0058
GSE53624 DNAJB4 11080 150012 -0.2095 0.0255
GSE63941 DNAJB4 11080 203810_at -1.2874 0.0746
GSE77861 DNAJB4 11080 203810_at -0.1321 0.7838
GSE97050 DNAJB4 11080 A_24_P393958 -0.6567 0.1702
SRP007169 DNAJB4 11080 RNAseq -0.4748 0.3177
SRP008496 DNAJB4 11080 RNAseq -0.0106 0.9757
SRP064894 DNAJB4 11080 RNAseq -0.1702 0.5734
SRP133303 DNAJB4 11080 RNAseq -0.0250 0.9158
SRP159526 DNAJB4 11080 RNAseq -0.3907 0.2361
SRP193095 DNAJB4 11080 RNAseq 0.1739 0.5194
SRP219564 DNAJB4 11080 RNAseq -0.2244 0.7222
TCGA DNAJB4 11080 RNAseq -0.1433 0.1236

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DNAJB4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DNAJB4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DNAJB4 11080 0 7 23
GSE20123 DNAJB4 11080 0 7 23
GSE43470 DNAJB4 11080 4 3 36
GSE46452 DNAJB4 11080 0 1 58
GSE47630 DNAJB4 11080 8 6 26
GSE54993 DNAJB4 11080 0 0 70
GSE54994 DNAJB4 11080 6 3 44
GSE60625 DNAJB4 11080 0 0 11
GSE74703 DNAJB4 11080 3 2 31
GSE74704 DNAJB4 11080 0 4 16
TCGA DNAJB4 11080 8 25 63

Total number of gains: 29; Total number of losses: 58; Total Number of normals: 401.  

 

Somatic mutations of DNAJB4:

 

Generating mutation plots.

 

Highly correlated genes for DNAJB4:

 

Showing top 20/478 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DNAJB4FIBIN0.757414303
DNAJB4FAM13C0.74831303
DNAJB4LRRFIP20.74752303
DNAJB4RNF2140.743209403
DNAJB4JMY0.729002303
DNAJB4XPC0.728524303
DNAJB4SLIT30.725985303
DNAJB4MTA30.714068303
DNAJB4CPEB40.712168303
DNAJB4DTNA0.710372303
DNAJB4CYYR10.70734504
DNAJB4ROR10.704131303
DNAJB4WNT60.703566303
DNAJB4IMPACT0.699706303
DNAJB4FUNDC20.695556403
DNAJB4MRVI10.693875504
DNAJB4EPG50.692602303
DNAJB4TMEM41B0.688488303
DNAJB4COBLL10.686797303
DNAJB4SBF20.686119504

For details and further investigation, click here