| Full name: sterile alpha motif domain containing 12 | Alias Symbol: FLJ39458 | ||
| Type: protein-coding gene | Cytoband: 8q24.11-q24.12 | ||
| Entrez ID: 401474 | HGNC ID: HGNC:31750 | Ensembl Gene: ENSG00000177570 | OMIM ID: 618073 |
| Drug and gene relationship at DGIdb | |||
Expression of SAMD12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAMD12 | 401474 | 238673_at | 0.4921 | 0.5104 | |
| GSE26886 | SAMD12 | 401474 | 238673_at | 0.4217 | 0.5306 | |
| GSE45670 | SAMD12 | 401474 | 238673_at | 0.7276 | 0.2054 | |
| GSE53622 | SAMD12 | 401474 | 48427 | 0.5919 | 0.0049 | |
| GSE53624 | SAMD12 | 401474 | 48427 | 0.2684 | 0.2170 | |
| GSE63941 | SAMD12 | 401474 | 238673_at | 3.8653 | 0.0098 | |
| GSE77861 | SAMD12 | 401474 | 238673_at | 0.7906 | 0.3500 | |
| GSE97050 | SAMD12 | 401474 | A_33_P3326225 | -0.0263 | 0.9426 | |
| SRP007169 | SAMD12 | 401474 | RNAseq | 2.3556 | 0.0000 | |
| SRP008496 | SAMD12 | 401474 | RNAseq | 2.7489 | 0.0000 | |
| SRP064894 | SAMD12 | 401474 | RNAseq | -0.0304 | 0.9450 | |
| SRP133303 | SAMD12 | 401474 | RNAseq | 0.5894 | 0.0827 | |
| SRP159526 | SAMD12 | 401474 | RNAseq | 0.7516 | 0.1726 | |
| SRP193095 | SAMD12 | 401474 | RNAseq | 0.0657 | 0.7718 | |
| SRP219564 | SAMD12 | 401474 | RNAseq | -0.5325 | 0.4966 | |
| TCGA | SAMD12 | 401474 | RNAseq | -0.0424 | 0.8610 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SAMD12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAMD12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAMD12 | 401474 | 19 | 1 | 10 | |
| GSE20123 | SAMD12 | 401474 | 20 | 1 | 9 | |
| GSE43470 | SAMD12 | 401474 | 23 | 0 | 20 | |
| GSE46452 | SAMD12 | 401474 | 26 | 0 | 33 | |
| GSE47630 | SAMD12 | 401474 | 24 | 0 | 16 | |
| GSE54993 | SAMD12 | 401474 | 0 | 20 | 50 | |
| GSE54994 | SAMD12 | 401474 | 37 | 1 | 15 | |
| GSE60625 | SAMD12 | 401474 | 0 | 4 | 7 | |
| GSE74703 | SAMD12 | 401474 | 19 | 0 | 17 | |
| GSE74704 | SAMD12 | 401474 | 13 | 1 | 6 | |
| TCGA | SAMD12 | 401474 | 67 | 2 | 27 |
Total number of gains: 248; Total number of losses: 30; Total Number of normals: 210.
Somatic mutations of SAMD12:
Generating mutation plots.
Highly correlated genes for SAMD12:
Showing top 20/410 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAMD12 | AP1M2 | 0.773947 | 3 | 0 | 3 |
| SAMD12 | RNF6 | 0.758014 | 3 | 0 | 3 |
| SAMD12 | TMEM209 | 0.752762 | 3 | 0 | 3 |
| SAMD12 | PRKCH | 0.737124 | 3 | 0 | 3 |
| SAMD12 | ACBD5 | 0.730109 | 3 | 0 | 3 |
| SAMD12 | TMEM30B | 0.718841 | 3 | 0 | 3 |
| SAMD12 | E2F8 | 0.718703 | 3 | 0 | 3 |
| SAMD12 | ZNF184 | 0.717536 | 4 | 0 | 4 |
| SAMD12 | PTPRF | 0.715979 | 3 | 0 | 3 |
| SAMD12 | CSTF2T | 0.713893 | 3 | 0 | 3 |
| SAMD12 | KIAA1522 | 0.705247 | 3 | 0 | 3 |
| SAMD12 | TDP1 | 0.704005 | 3 | 0 | 3 |
| SAMD12 | ZC3HAV1 | 0.693232 | 3 | 0 | 3 |
| SAMD12 | KATNA1 | 0.691373 | 3 | 0 | 3 |
| SAMD12 | DCLRE1A | 0.686852 | 3 | 0 | 3 |
| SAMD12 | SLC22A5 | 0.685584 | 3 | 0 | 3 |
| SAMD12 | ARF3 | 0.684778 | 3 | 0 | 3 |
| SAMD12 | PRPS2 | 0.682894 | 4 | 0 | 4 |
| SAMD12 | BORA | 0.68211 | 3 | 0 | 3 |
| SAMD12 | E2F2 | 0.676134 | 3 | 0 | 3 |
For details and further investigation, click here
