| Full name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | Alias Symbol: TFIIIB150|TFC5|TFIIIB90|KIAA1689|HSA238520|KIAA1241 | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 55814 | HGNC ID: HGNC:13652 | Ensembl Gene: ENSG00000145734 | OMIM ID: 607012 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of BDP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BDP1 | 55814 | 226290_at | -0.4370 | 0.2715 | |
| GSE26886 | BDP1 | 55814 | 226290_at | 0.0298 | 0.9393 | |
| GSE45670 | BDP1 | 55814 | 226290_at | -0.2379 | 0.0345 | |
| GSE53622 | BDP1 | 55814 | 78184 | -0.1094 | 0.2035 | |
| GSE53624 | BDP1 | 55814 | 52778 | -0.2843 | 0.0201 | |
| GSE63941 | BDP1 | 55814 | 226290_at | -0.8125 | 0.1138 | |
| GSE77861 | BDP1 | 55814 | 226290_at | -0.1463 | 0.7235 | |
| GSE97050 | BDP1 | 55814 | A_24_P940776 | 0.0314 | 0.8816 | |
| SRP007169 | BDP1 | 55814 | RNAseq | 1.0165 | 0.0178 | |
| SRP008496 | BDP1 | 55814 | RNAseq | 0.8593 | 0.0011 | |
| SRP064894 | BDP1 | 55814 | RNAseq | -0.3117 | 0.2178 | |
| SRP133303 | BDP1 | 55814 | RNAseq | -0.0481 | 0.5822 | |
| SRP159526 | BDP1 | 55814 | RNAseq | -0.4933 | 0.1036 | |
| SRP193095 | BDP1 | 55814 | RNAseq | -0.2017 | 0.0510 | |
| SRP219564 | BDP1 | 55814 | RNAseq | -0.6492 | 0.0780 | |
| TCGA | BDP1 | 55814 | RNAseq | -0.1539 | 0.0019 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by BDP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BDP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BDP1 | 55814 | 1 | 13 | 16 | |
| GSE20123 | BDP1 | 55814 | 1 | 13 | 16 | |
| GSE43470 | BDP1 | 55814 | 1 | 13 | 29 | |
| GSE46452 | BDP1 | 55814 | 0 | 28 | 31 | |
| GSE47630 | BDP1 | 55814 | 1 | 19 | 20 | |
| GSE54993 | BDP1 | 55814 | 8 | 1 | 61 | |
| GSE54994 | BDP1 | 55814 | 4 | 18 | 31 | |
| GSE60625 | BDP1 | 55814 | 0 | 0 | 11 | |
| GSE74703 | BDP1 | 55814 | 1 | 9 | 26 | |
| GSE74704 | BDP1 | 55814 | 1 | 6 | 13 | |
| TCGA | BDP1 | 55814 | 5 | 50 | 41 |
Total number of gains: 23; Total number of losses: 170; Total Number of normals: 295.
Somatic mutations of BDP1:
Generating mutation plots.
Highly correlated genes for BDP1:
Showing top 20/371 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BDP1 | INO80D | 0.808731 | 3 | 0 | 3 |
| BDP1 | PIBF1 | 0.80494 | 3 | 0 | 3 |
| BDP1 | SGPP1 | 0.779665 | 3 | 0 | 3 |
| BDP1 | MRPS27 | 0.774072 | 4 | 0 | 4 |
| BDP1 | KIF3A | 0.772441 | 3 | 0 | 3 |
| BDP1 | TUBB2A | 0.772194 | 3 | 0 | 3 |
| BDP1 | PPP2CA | 0.764449 | 3 | 0 | 3 |
| BDP1 | THOC7 | 0.764367 | 3 | 0 | 3 |
| BDP1 | WDR41 | 0.763919 | 3 | 0 | 3 |
| BDP1 | PHF11 | 0.763567 | 3 | 0 | 3 |
| BDP1 | MRPL40 | 0.756473 | 3 | 0 | 3 |
| BDP1 | NDUFS1 | 0.747262 | 3 | 0 | 3 |
| BDP1 | ACBD5 | 0.744202 | 4 | 0 | 4 |
| BDP1 | PGM1 | 0.740882 | 3 | 0 | 3 |
| BDP1 | CRYZ | 0.740726 | 3 | 0 | 3 |
| BDP1 | DDX46 | 0.737537 | 4 | 0 | 3 |
| BDP1 | C11orf54 | 0.736711 | 4 | 0 | 4 |
| BDP1 | BNIP3 | 0.735087 | 3 | 0 | 3 |
| BDP1 | PLK2 | 0.734081 | 3 | 0 | 3 |
| BDP1 | PCBD2 | 0.728296 | 3 | 0 | 3 |
For details and further investigation, click here
